Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. (Q36850905)

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27 February 2020

title

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway (English)

1 reference

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27 February 2020

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corrigendum / erratum

Erratum: Corrigendum: Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

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author

Lewis C. Cantley

17

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27 February 2020

Costas A Lyssiotis

2

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27 February 2020

Ng Shyh-Chang

10

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27 February 2020

16

Ronald A DePinho

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27 February 2020

12

Jason B Fleming

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27 February 2020

5

Sujun Hua

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27 February 2020

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3

Haoqiang Ying

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27 February 2020

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9

Edouard Mullarky

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27 February 2020

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John M Asara

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27 February 2020

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13

Nabeel Bardeesy

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27 February 2020

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1

Jaekyoung Son

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27 February 2020

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15

Marcia C Haigis

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27 February 2020

author name string

Xiaoxu Wang

4

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27 February 2020

Matteo Ligorio

6

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27 February 2020

Rushika M Perera

7

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27 February 2020

Cristina R Ferrone

8

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27 February 2020

Ya'an Kang

11

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27 February 2020

Alec C Kimmelman

18

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27 February 2020

language of work or name

English

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publication date

27 March 2013

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27 February 2020

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27 February 2020

volume

496

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27 February 2020

page(s)

101-105

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27 February 2020

issue

7443

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https://scigraph.springernature.com/pub.10.1038/nature12040

27 February 2020

exact match

0 references

cites work

Links between metabolism and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

A positive/negative ion-switching, targeted mass spectrometry-based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Full-length human glutaminase in complex with an allosteric inhibitor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Targeting cancer metabolism: a therapeutic window opens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Pancreatic cancers require autophagy for tumor growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Glutamine: pleiotropic roles in tumor growth and stress resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Regulation of cancer cell metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

The dicarboxylate carrier plays a role in mitochondrial malate transport and in the regulation of glucose-stimulated insulin secretion from rat pancreatic beta cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Targeting mitochondrial glutaminase activity inhibits oncogenic transformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Glutamine addiction: a new therapeutic target in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Tumor suppressors and cell metabolism: a recipe for cancer growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Immortal human pancreatic duct epithelial cell lines with near normal genotype and phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Glucose addiction of TSC null cells is caused by failed mTORC1-dependent balancing of metabolic demand with supply

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656466

Understanding the Warburg effect: the metabolic requirements of cell proliferation

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE12040

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE12040

1 reference

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Dimensions Publication ID

27 February 2020

0 references

1 reference

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27 February 2020

1 reference

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