CD95, BIM and T cell homeostasis (Q37526364)

20 August 2017

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title

CD95, BIM and T cell homeostasis (English)

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20 August 2017

Philippe Bouillet

1

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author name string

Lorraine A O'Reilly

series ordinal

2

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PubMed ID

19543226

20 August 2017

language of work or name

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1 July 2009

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Nature Reviews Immunology

20 August 2017

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20 August 2017

9

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20 August 2017

7

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20 August 2017

514-519

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Caspase-8 serves both apoptotic and nonapoptotic roles

20 August 2017

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Lineage commitment in the progeny of murine hematopoietic preprogenitor cells: influence of thrombopoietin and interleukin 5.

21 January 2018

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The role of BH3-only proteins in the immune system

31 March 2020

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The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

31 March 2020

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Bim: a novel member of the Bcl-2 family that promotes apoptosis

31 March 2020

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CD95's deadly mission in the immune system

31 March 2020

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Death-inducing functions of ligands of the tumor necrosis factor family: a Sanhedrin verdict.

31 March 2020

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Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity

31 March 2020

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Downregulation of Fas ligand by shedding

31 March 2020

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Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations

31 March 2020

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Apoptosis by death factor

31 March 2020

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The many roles of FAS receptor signaling in the immune system

31 March 2020

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Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

31 March 2020

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Delivering the kiss of death

31 March 2020

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ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death.

31 March 2020

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Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

31 March 2020

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Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

31 March 2020

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A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

31 March 2020

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A role for FADD in T cell activation and development

31 March 2020

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Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

31 March 2020

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Bcl-2-regulated apoptosis: mechanism and therapeutic potential

31 March 2020

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How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

31 March 2020

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How the Bcl-2 family of proteins interact to regulate apoptosis.

31 March 2020

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The Bcl-2 family in autoimmune and degenerative disorders

31 March 2020

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Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

31 March 2020

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The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane

31 March 2020

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Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

31 March 2020

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Proliferation is a prerequisite for bacterial superantigen-induced T cell apoptosis in vivo

31 March 2020

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Peripheral T cells undergoing superantigen-induced apoptosis in vivo express B220 and upregulate Fas and Fas ligand

31 March 2020

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Expression of B220 on activated T cell blasts precedes apoptosis

31 March 2020

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Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide

31 March 2020

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Fas ligand mediates activation-induced cell death in human T lymphocytes

31 March 2020

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Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

31 March 2020

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Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

31 March 2020

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Activation-induced cell death in T cells

31 March 2020

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Homeostatic regulation of CD8+ T cells after antigen challenge in the absence of Fas (CD95)

31 March 2020

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Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo

31 March 2020

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Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells

31 March 2020

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Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

31 March 2020

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T-lymphocyte death during shutdown of an immune response

31 March 2020

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The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

31 March 2020

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Residual antigen presentation after influenza virus infection affects CD8 T cell activation and migration

31 March 2020

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Persistent antigen presentation after acute vesicular stomatitis virus infection

31 March 2020

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

31 March 2020

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

31 March 2020

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Multisite phosphorylation regulates Bim stability and apoptotic activity

31 March 2020

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Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim

31 March 2020

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Cytokine-induced survival of activated T cells in vitro and in vivo

31 March 2020

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Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

31 March 2020

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Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity

31 March 2020

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Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction

31 March 2020

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Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

31 March 2020

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CD8+ T cell contraction is controlled by early inflammation.

31 March 2020

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Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity

31 March 2020

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Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction

31 March 2020

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Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity

31 March 2020

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

31 March 2020

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Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, diminishes lymphoproliferation in the Fas -deficient MRL/lpr(-/-) murine model of autoimmune lymphoproliferative syndrome (ALPS)

31 March 2020

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T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions.

31 March 2020

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12 December 2020

bcl-2 transgenic Lpr mice show profound enhancement of lymphadenopathy

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12 December 2020

Role of Bim and other Bcl-2 family members in autoimmune and degenerative diseases

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12 December 2020

BH3-only proteins and their roles in programmed cell death

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12 December 2020

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

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12 December 2020

Developmental biology of T cells in T cell-receptor transgenic mice

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12 December 2020

Identifiers

DOI

10.1038/NRI2570

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20 August 2017

1 reference

PubMed ID

19543226