The current structural and functional understanding of APOBEC deaminases (Q37528123)

20 August 2017

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title

The current structural and functional understanding of APOBEC deaminases (English)

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20 August 2017

Ronda Bransteitter

1

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20 August 2017

Courtney Prochnow

series ordinal

2

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20 August 2017

Xiaojiang S Chen

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3

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20 August 2017

language of work or name

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23 June 2009

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Cellular and Molecular Life Sciences

20 August 2017

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20 August 2017

66

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20 August 2017

19

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20 August 2017

3137-3147

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https://scigraph.springernature.com/pub.10.1007/s00018-009-0070-y

20 August 2017

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cites work

RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00018-009-0070-Y

Target cell APOBEC3C can induce limited G-to-A mutation in HIV-1

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS00018-009-0070-Y

Enzymatically active APOBEC3G is required for efficient inhibition of human immunodeficiency virus type 1.

21 January 2018

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12 December 2020

Functional domain organization of human APOBEC3G.

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12 December 2020

An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22

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12 December 2020

APOBEC3G DNA deaminase acts processively 3' --> 5' on single-stranded DNA.

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12 December 2020

RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1

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12 December 2020

Human immunodeficiency virus type 1 Vif inhibits packaging and antiviral activity of a degradation-resistant APOBEC3G variant

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12 December 2020

Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression

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12 December 2020

Molecular cloning of an apolipoprotein B messenger RNA editing protein

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12 December 2020

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

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12 December 2020

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

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12 December 2020

Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

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12 December 2020

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

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12 December 2020

APOBEC3G inhibits elongation of HIV-1 reverse transcripts

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12 December 2020

Aberrant AID expression and human cancer development

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12 December 2020

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

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12 December 2020

Mechanisms of APOBEC3G-catalyzed processive deamination of deoxycytidine on single-stranded DNA.

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12 December 2020

Cytidine deaminases APOBEC3G and APOBEC3F interact with human immunodeficiency virus type 1 integrase and inhibit proviral DNA formation

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12 December 2020

APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase

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12 December 2020

Antiviral function of APOBEC3G can be dissociated from cytidine deaminase activity

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12 December 2020

APOBEC3G incorporation into human immunodeficiency virus type 1 particles

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12 December 2020

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

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12 December 2020

Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma

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12 December 2020

The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA

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12 December 2020

Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif

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12 December 2020

APOBEC3G inhibits DNA strand transfer during HIV-1 reverse transcription.

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12 December 2020

Identification of two distinct human immunodeficiency virus type 1 Vif determinants critical for interactions with human APOBEC3G and APOBEC3F.

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12 December 2020

Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications

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12 December 2020

DNA deamination in immunity: AID in the context of its APOBEC relatives.

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12 December 2020

A model for oligomeric regulation of APOBEC3G cytosine deaminase-dependent restriction of HIV

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12 December 2020

APOBEC3G is incorporated into virus-like particles by a direct interaction with HIV-1 Gag nucleocapsid protein

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12 December 2020

Hypermutation by intersegmental transfer of APOBEC3G cytidine deaminase

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12 December 2020

Nanostructures of APOBEC3G support a hierarchical assembly model of high molecular mass ribonucleoprotein particles from dimeric subunits.

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12 December 2020

Amino-terminal region of the human immunodeficiency virus type 1 nucleocapsid is required for human APOBEC3G packaging

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12 December 2020

Mutational comparison of the single-domained APOBEC3C and double-domained APOBEC3F/G anti-retroviral cytidine deaminases provides insight into their DNA target site specificities

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12 December 2020

Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome

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12 December 2020

Human APOBEC3B is a potent inhibitor of HIV-1 infectivity and is resistant to HIV-1 Vif.

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12 December 2020

Function analysis of sequences in human APOBEC3G involved in Vif-mediated degradation.

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12 December 2020

Natural variation in Vif: differential impact on APOBEC3G/3F and a potential role in HIV-1 diversification

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12 December 2020

Cytidine deaminase. The 2.3 A crystal structure of an enzyme: transition-state analog complex

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12 December 2020

Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G

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12 December 2020

A single amino acid of APOBEC3G controls its species-specific interaction with virion infectivity factor (Vif).

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12 December 2020

Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.

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12 December 2020

In Vitro Deamination of Cytosine to Uracil in Single-stranded DNA by Apolipoprotein B Editing Complex Catalytic Subunit 1 (APOBEC1)

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12 December 2020

Constitutive expression of AID leads to tumorigenesis

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12 December 2020

Human immunodeficiency virus type 1 Vif functionally interacts with diverse APOBEC3 cytidine deaminases and moves with them between cytoplasmic sites of mRNA metabolism

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12 December 2020

The 1.48 A resolution crystal structure of the homotetrameric cytidine deaminase from mouse.

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12 December 2020

APOBEC3G: an intracellular centurion

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12 December 2020

DNA deamination mediates innate immunity to retroviral infection

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12 December 2020

Identification of APOBEC3DE as another antiretroviral factor from the human APOBEC family

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12 December 2020

The interaction between HIV-1 Gag and APOBEC3G.

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12 December 2020

HIV-1 Vif Blocks the Antiviral Activity of APOBEC3G by Impairing Both Its Translation and Intracellular Stability

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12 December 2020

Biochemical activities of highly purified, catalytically active human APOBEC3G: correlation with antiviral effect.

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12 December 2020

Dissecting APOBEC3G substrate specificity by nucleoside analog interference.

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12 December 2020

Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

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12 December 2020

APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G

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12 December 2020

Hypermutation of hepatitis B virus genomes by APOBEC3G, APOBEC3C and APOBEC3H.

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12 December 2020

Inhibition of hepatitis B virus replication by APOBEC3G.

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12 December 2020

Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo

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12 December 2020

An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model

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12 December 2020

Cytidine deamination of retroviral DNA by diverse APOBEC proteins

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12 December 2020

The p27 catalytic subunit of the apolipoprotein B mRNA editing enzyme is a cytidine deaminase.

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12 December 2020

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12 December 2020

Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA.

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12 December 2020

Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G.

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12 December 2020

Viral RNA is required for the association of APOBEC3G with human immunodeficiency virus type 1 nucleoprotein complexes

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12 December 2020

Insights into DNA deaminases

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12 December 2020

Regulation of Apobec3F and human immunodeficiency virus type 1 Vif by Vif-Cul5-ElonB/C E3 ubiquitin ligase

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12 December 2020

Differential requirement for conserved tryptophans in human immunodeficiency virus type 1 Vif for the selective suppression of APOBEC3G and APOBEC3F.

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12 December 2020

Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions

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12 December 2020

Identification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and Virion encapsidation

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12 December 2020

APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons

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12 December 2020

Post-translational regulation of activation-induced cytidine deaminase

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12 December 2020

Escherichia coli cytidine deaminase provides a molecular model for ApoB RNA editing and a mechanism for RNA substrate recognition

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12 December 2020

Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor

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12 December 2020

Model structure of human APOBEC3G

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12 December 2020

Immunity through DNA deamination

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12 December 2020

APOBEC3G multimers are recruited to the plasma membrane for packaging into human immunodeficiency virus type 1 virus-like particles in an RNA-dependent process requiring the NC basic linker

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12 December 2020

Complementary function of the two catalytic domains of APOBEC3G.

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12 December 2020

Structure of human cytidine deaminase bound to a potent inhibitor

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12 December 2020

The roles of APE1, APE2, DNA polymerase beta and mismatch repair in creating S region DNA breaks during antibody class switch

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12 December 2020

APOBEC-mediated interference with hepadnavirus production

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12 December 2020

HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation

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12 December 2020

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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12 December 2020

The APOBEC-2 crystal structure and functional implications for the deaminase AID

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12 December 2020

A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor

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12 December 2020

The Vif Protein of HIV Triggers Degradation of the Human Antiretroviral DNA Deaminase APOBEC3G

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12 December 2020

Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G

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12 December 2020

Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business

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12 December 2020

Twin gradients in APOBEC3 edited HIV-1 DNA reflect the dynamics of lentiviral replication

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12 December 2020

Inhibition of tRNA₃(Lys)-primed reverse transcription by human APOBEC3G during human immunodeficiency virus type 1 replication

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12 December 2020

Mutations in activation-induced cytidine deaminase in patients with hyper IgM syndrome

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12 December 2020

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

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12 December 2020

Brca1 in immunoglobulin gene conversion and somatic hypermutation

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12 December 2020

G to A hypermutation of hepatitis B virus.

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12 December 2020

The DNA deaminase activity of human APOBEC3G is required for Ty1, MusD, and human immunodeficiency virus type 1 restriction

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12 December 2020

Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration

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12 December 2020

A single amino acid determinant governs the species-specific sensitivity of APOBEC3G to Vif action

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12 December 2020

The intrinsic antiretroviral factor APOBEC3B contains two enzymatically active cytidine deaminase domains

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12 December 2020

Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium

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12 December 2020

The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif

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12 December 2020

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

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12 December 2020

Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA.

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12 December 2020

APOBEC3G subunits self-associate via the C-terminal deaminase domain

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12 December 2020

APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo

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12 December 2020

10.1007/S00018-009-0070-Y

Identifiers

DOI

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20 August 2017

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