A cell biological view of Toll-like receptor function: regulation through compartmentalization. (Q37531879)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19556980%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

review article

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title

A cell biological view of Toll-like receptor function: regulation through compartmentalization (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19556980%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

0 references

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19556980%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Jonathan C Kagan

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19556980%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

publication date

26 June 2009

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19556980%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

1 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19556980%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

9

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1 February 2020

page(s)

535-542

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19556980%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

issue

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19556980%20AND%20SRC:MED&resulttype=core&format=json

TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway

1 February 2020

cites work

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Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

23 August 2017

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The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

23 August 2017

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Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

23 August 2017

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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

23 August 2017

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TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

23 August 2017

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23 August 2017

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Toll-like receptors in systemic autoimmune disease

23 August 2017

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Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

23 August 2017

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A Tlr7 translocation accelerates systemic autoimmunity in murine lupus

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Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

23 August 2017

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The dsRNA binding site of human Toll-like receptor 3.

23 August 2017

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The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction

23 August 2017

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Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity

23 August 2017

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The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

23 August 2017

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23 August 2017

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RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.

23 August 2017

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Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus

23 August 2017

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23 August 2017

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Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

23 August 2017

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Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

23 August 2017

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Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

23 August 2017

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TIRAP: an adapter molecule in the Toll signaling pathway

23 August 2017

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MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

23 August 2017

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Innate immunity: the virtues of a nonclonal system of recognition

23 August 2017

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Approaching the asymptote? Evolution and revolution in immunology

23 August 2017

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Ligand-induced conformational changes allosterically activate Toll-like receptor 9.

23 August 2017

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Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

6 September 2017

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The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets

6 September 2017

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CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation

6 September 2017

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Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling

6 September 2017

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Cathepsins are required for Toll-like receptor 9 responses

14 September 2017

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Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice

14 September 2017

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Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

14 September 2017

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TLR9 signals after translocating from the ER to CpG DNA in the lysosome

14 September 2017

1 reference

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Subcellular localization of Toll-like receptor 3 in human dendritic cells

14 September 2017

1 reference

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

14 September 2017

1 reference

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The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

14 September 2017

1 reference

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Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934928

Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA.

25 June 2018

1 reference

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Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14.

25 June 2018

1 reference

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Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934928

Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA.

2 September 2018

1 reference

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MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934928

2 September 2018

Identifiers

DOI

10.1038/NRI2587

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19556980%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19556980%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference