Innate immune recognition of viral infection (Q24498364)

Toll-like receptor control of the adaptive immune responses

Europe PubMed Central

title

Innate immune recognition of viral infection (English)

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author

Shizuo Akira

series ordinal

2

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author name string

Taro Kawai

series ordinal

1

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language of work or name

English

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publication date

February 2006

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published in

Nature Immunology

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volume

7

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page(s)

131-7

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issue

2

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cites work

1 reference

Type I interferons (alpha/beta) in immunity and autoimmunity

21 January 2018

1 reference

Toll-like receptors in innate immunity

21 January 2018

1 reference

Innate immunity: the virtues of a nonclonal system of recognition

21 January 2018

1 reference

Innate immune recognition

21 January 2018

1 reference

Toll-like receptors: critical proteins linking innate and acquired immunity

21 January 2018

1 reference

21 January 2018

1 reference

Links between innate and adaptive immunity via type I interferon

21 January 2018

1 reference

New aspects of IFN-alpha/beta signalling in immunity, oncogenesis and bone metabolism

21 January 2018

1 reference

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

21 January 2018

1 reference

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

21 January 2018

1 reference

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

1 reference

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

21 January 2018

1 reference

Recognition of single-stranded RNA viruses by Toll-like receptor 7

21 January 2018

1 reference

TLR9-Dependent Recognition of MCMV by IPC and DC Generates Coordinated Cytokine Responses that Activate Antiviral NK Cell Function

21 January 2018

1 reference

Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

21 January 2018

1 reference

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

21 January 2018

1 reference

Cell type-specific involvement of RIG-I in antiviral response

21 January 2018

1 reference

IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors

21 January 2018

1 reference

Plasmacytoid dendritic cells in immunity

21 January 2018

1 reference

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

1 reference

Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

21 January 2018

1 reference

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets

21 January 2018

1 reference

Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

21 January 2018

1 reference

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

21 January 2018

1 reference

Toll-like receptor signalling

21 January 2018

1 reference

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

1 reference

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

1 reference

Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling

21 January 2018

1 reference

Identification of a human NF-kappaB-activating protein, TAB3

21 January 2018

1 reference

Essential function for the kinase TAK1 in innate and adaptive immune responses.

21 January 2018

1 reference

Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

21 January 2018

1 reference

Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

21 January 2018

1 reference

IRF-7 is the master regulator of type-I interferon-dependent immune responses

21 January 2018

1 reference

Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells

21 January 2018

1 reference

Regulation of IFN regulatory factor-7 and IFN-alpha production by enveloped virus and lipopolysaccharide in human plasmacytoid dendritic cells

21 January 2018

1 reference

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction

21 January 2018

1 reference

Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

21 January 2018

1 reference

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

21 January 2018

1 reference

The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling

21 January 2018

1 reference

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

21 January 2018

1 reference

Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

21 January 2018

1 reference

Toll-like receptor 3 promotes cross-priming to virus-infected cells.

21 January 2018

1 reference

Subcellular localization of Toll-like receptor 3 in human dendritic cells

21 January 2018

1 reference

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

21 January 2018

1 reference

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

21 January 2018

1 reference

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

21 January 2018

1 reference

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

21 January 2018

1 reference

Triggering the interferon antiviral response through an IKK-related pathway

21 January 2018

1 reference

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

21 January 2018

1 reference

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

21 January 2018

1 reference

The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

21 January 2018

1 reference

Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection

21 January 2018

1 reference

Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

21 January 2018

1 reference

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

21 January 2018

1 reference

Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signaling

21 January 2018

1 reference

Does Toll-like receptor 3 play a biological role in virus infections?

21 January 2018

1 reference

TLR-independent induction of dendritic cell maturation and adaptive immunity by negative-strand RNA viruses.

21 January 2018

1 reference

Replication-dependent potent IFN-alpha induction in human plasmacytoid dendritic cells by a single-stranded RNA virus

21 January 2018

1 reference

mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties

21 January 2018

1 reference

Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradation

21 January 2018

1 reference

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

21 January 2018

1 reference

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

21 January 2018

1 reference

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

21 January 2018

1 reference

A FADD-dependent innate immune mechanism in mammalian cells

21 January 2018

1 reference

The immune response of Drosophila

21 January 2018

1 reference

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

21 January 2018

1 reference

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

21 January 2018

1 reference

VISA is an adapter protein required for virus-triggered IFN-beta signaling

21 January 2018

1 reference

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

21 January 2018

1 reference

21 January 2018

Hitching RIG to action

1 reference

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence

21 January 2018

1 reference

Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling

21 January 2018

1 reference

Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I

21 January 2018

1 reference

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

21 January 2018

1 reference

Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease

21 January 2018

1 reference

Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes.

21 January 2018

1 reference

Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.

21 January 2018

1 reference

Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA

21 January 2018

1 reference

Activation of interferon regulatory factor 3 in response to DNA-damaging agents

21 January 2018

1 reference

The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation

21 January 2018

1 reference

Unresponsiveness of MyD88-deficient mice to endotoxin

21 January 2018

1 reference

7 January 2021

Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes

1 reference

7 January 2021

Endotoxin-induced maturation of MyD88-deficient dendritic cells

1 reference

7 January 2021

Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activation

1 reference

7 January 2021

The KSHV immediate-early transcription factor RTA encodes ubiquitin E3 ligase activity that targets IRF7 for proteosome-mediated degradation

1 reference

7 January 2021