Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK. (Q37543714)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24474794%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK (English)

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6 March 2020

4

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6 March 2020

Lionel Chow

6

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6 March 2020

Koenraad K Norga

16

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6 March 2020

Benoit Viollet

17

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6 March 2020

15

Jeroen Poels

1 reference

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6 March 2020

author name string

Xiaona Liu

1

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6 March 2020

Rishi Raj Chhipa

2

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6 March 2020

Shabnam Pooya

3

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6 March 2020

Sara Yachyshin

5

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6 March 2020

Ashish Kumar

7

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6 March 2020

Xuan Zhou

8

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6 March 2020

Ying Sun

9

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6 March 2020

Brian Quinn

10

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6 March 2020

Christopher McPherson

11

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6 March 2020

Ronald E Warnick

12

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6 March 2020

Ady Kendler

13

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6 March 2020

Shailendra Giri

14

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6 March 2020

Gregory A Grabowski

18

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6 March 2020

Biplab Dasgupta

19

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6 March 2020

language of work or name

English

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publication date

13 January 2014

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Proceedings of the National Academy of Sciences of the United States of America

6 March 2020

published in

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volume

111

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6 March 2020

page(s)

E435-44

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6 March 2020

issue

4

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Androgens upregulate Cdc25C protein by inhibiting its proteasomal and lysosomal degradation pathways

6 March 2020

cites work

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23 August 2017

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Chemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosis

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AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

23 August 2017

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Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain

23 August 2017

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Identification of aneuploidy-selective antiproliferation compounds

23 August 2017

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AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia

23 August 2017

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23 August 2017

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Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

23 August 2017

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23 August 2017

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Prognostic significance of AMP-activated protein kinase expression and modifying effect of MAPK3/1 in colorectal cancer

23 August 2017

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Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation

23 August 2017

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23 August 2017

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Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E

23 August 2017

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Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth

23 August 2017

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The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

23 August 2017

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Tumor suppressors and cell metabolism: a recipe for cancer growth

23 August 2017

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AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development

23 August 2017

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AMPK phosphorylation of raptor mediates a metabolic checkpoint

23 August 2017

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Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.

23 August 2017

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PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

23 August 2017

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23 August 2017

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mTOR and cancer: insights into a complex relationship

23 August 2017

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5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments

23 August 2017

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Fatty acid synthase and cancer: new application of an old pathway

23 August 2017

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

23 August 2017

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23 August 2017

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23 August 2017

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AMPK activation by oncogenesis is required to maintain cancer cell proliferation in astrocytic tumors

23 August 2017

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Cells lacking the fumarase tumor suppressor are protected from apoptosis through a hypoxia-inducible factor-independent, AMPK-dependent mechanism

6 September 2017

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Deregulated MYC expression induces dependence upon AMPK-related kinase 5.

6 September 2017

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Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family.

6 September 2017

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Activation of glycogen phosphorylase with 5-aminoimidazole-4-carboxamide riboside (AICAR). Assessment of glycogen as a precursor of mannosyl residues in glycoconjugates

6 September 2017

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Potent anti-proliferative effects of metformin on trastuzumab-resistant breast cancer cells via inhibition of erbB2/IGF-1 receptor interactions.

6 September 2017

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AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells.

6 September 2017

1 reference

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Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner

14 September 2017

1 reference

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Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro

14 September 2017

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Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice

14 September 2017

1 reference

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Inhibition of AMP-activated protein kinase sensitizes cancer cells to cisplatin-induced apoptosis via hyper-induction of p53.

14 September 2017

1 reference

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Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells

14 September 2017

1 reference

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Energy-dependent regulation of cell structure by AMP-activated protein kinase

14 September 2017

1 reference

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AICAR potentiates ROS production induced by chronic high glucose: roles of AMPK in pancreatic beta-cell apoptosis

14 September 2017

1 reference

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AMP-dependent protein kinase alpha 2 isoform promotes hypoxia-induced VEGF expression in human glioblastoma

14 September 2017

1 reference

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5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase

14 September 2017

1 reference

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Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype

14 September 2017

1 reference

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Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study

14 September 2017

1 reference

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Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.

14 September 2017

1 reference

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5'-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat.

14 September 2017

1 reference

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AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside

25 June 2018

1 reference

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Alteration of purine metabolism by AICA-riboside in human B lymphoblasts

25 June 2018

1 reference

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AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation.

25 June 2018

1 reference

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Mitotic kinase dynamics of the active form of AMPK (phospho-AMPKalphaThr172) in human cancer cells.

1 September 2018

1 reference

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Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle

1 September 2018

1 reference

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Critical roles of AMP-activated protein kinase in constitutive tolerance of cancer cells to nutrient deprivation and tumor formation

1 September 2018

1 reference

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Redox regulation of Cdc25C.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910576

AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes.

1 September 2018

1 reference

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5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase-Independent Effect on Glucokinase Translocation

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1311121111

21 January 2018

Identifiers

DOI

10.1073/PNAS.1311121111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24474794%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

0 references

1 reference

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6 March 2020

1 reference

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