Predicting intrinsic disorder in proteins: an overview (Q37549950)

21 August 2017

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title

Predicting intrinsic disorder in proteins: an overview (English)

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21 August 2017

Bo He

1

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21 August 2017

Kejun Wang

2

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21 August 2017

Yunlong Liu

3

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21 August 2017

Bin Xue

4

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21 August 2017

Vladimir N Uversky

5

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21 August 2017

A Keith Dunker

6

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21 August 2017

publication date

1 August 2009

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21 August 2017

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21 August 2017

volume

19

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21 August 2017

issue

8

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21 August 2017

page(s)

929-949

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https://scigraph.springernature.com/pub.10.1038/cr.2009.87

21 August 2017

exact match

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cites work

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Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions.

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Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins.

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A careful disorderliness in the proteome: sites for interaction and targets for future therapies.

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The role of structural disorder in the function of RNA and protein chaperones

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Coupling of local folding to site-specific binding of proteins to DNA

21 January 2018

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A Theory of the Structure and Process of Formation of Antibodies*

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Preformed structural elements feature in partner recognition by intrinsically unstructured proteins

21 January 2018

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Reconciling binding mechanisms of intrinsically disordered proteins.

21 January 2018

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Linking folding and binding

21 January 2018

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Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms

21 January 2018

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Intrinsically unstructured proteins

21 January 2018

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Natively unfolded proteins: a point where biology waits for physics

21 January 2018

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Dynamic behavior of an intrinsically unstructured linker domain is conserved in the face of negligible amino acid sequence conservation

21 January 2018

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Intrinsically disordered protein

21 January 2018

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Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Natively disordered proteins: functions and predictions

21 January 2018

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Characterization of the Structural Features and Interactions of Sclerostin: MOLECULAR INSIGHT INTO A KEY REGULATOR OF Wnt-MEDIATED BONE FORMATION

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Presence of transient helical segments in the galanin-like peptide evident from (1)H NMR, circular dichroism, and prediction studies

21 January 2018

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Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

21 January 2018

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DisProt: the Database of Disordered Proteins

21 January 2018

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The conformation properties of proteins in solution

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Sequence complexity of disordered protein

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Exploiting heterogeneous sequence properties improves prediction of protein disorder.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Length-dependent prediction of protein intrinsic disorder.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

FoldIndex: a simple tool to predict whether a given protein sequence is intrinsically unfolded

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

GlobPlot: Exploring protein sequences for globularity and disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Protein disorder prediction: implications for structural proteomics

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Prediction of disordered regions in proteins from position specific score matrices

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

The DISOPRED server for the prediction of protein disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Protein structure prediction servers at University College London

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

To be folded or to be unfolded?

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

FoldUnfold: web server for the prediction of disordered regions in protein chain.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

RONN: the bio-basis function neural network technique applied to the detection of natively disordered regions in proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Protein disorder prediction by condensed PSSM considering propensity for order or disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

iPDA: integrated protein disorder analyzer

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Spritz: a server for the prediction of intrinsically disordered regions in protein sequences using kernel machines.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

PrDOS: prediction of disordered protein regions from amino acid sequence

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Comparing and combining predictors of mostly disordered proteins.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

The intrinsically disordered C-terminal domain of the measles virus nucleoprotein interacts with the C-terminal domain of the phosphoprotein via two distinct sites and remains predominantly unfolded

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Combining prediction, computation and experiment for the characterization of protein disorder.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Studies of the RNA degradosome-organizing domain of the Escherichia coli ribonuclease RNase E.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

The C-terminal domain of the measles virus nucleoprotein is intrinsically disordered and folds upon binding to the C-terminal moiety of the phosphoprotein

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

The C-terminal domain of measles virus nucleoprotein belongs to the class of intrinsically disordered proteins that fold upon binding to their physiological partner

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Structural basis for the attachment of a paramyxoviral polymerase to its template

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Recognition of enolase in the Escherichia coli RNA degradosome

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Multiple intrinsically disordered sequences alter DNA binding by the homeodomain of the Drosophila hox protein ultrabithorax

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Evolutionary rate heterogeneity in proteins with long disordered regions.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Tight regulation of unstructured proteins: from transcript synthesis to protein degradation

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Overproduction, crystallization and preliminary crystallographic analysis of a novel human DNA-repair enzyme that recognizes oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.87

Large-scale analysis of thermostable, mammalian proteins provides insights into the intrinsically disordered proteome

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Uncovering the unfoldome: enriching cell extracts for unstructured proteins by acid treatment

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Proteomic studies of the intrinsically unstructured mammalian proteome.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Proteomics studies confirm the presence of alternative protein isoforms on a large scale

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Predicting protein disorder and induced folding: from theoretical principles to practical applications.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Prediction of protein disorder at the domain level

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

A practical overview of protein disorder prediction methods

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Progress from CASP6 to CASP7.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Assessment of disorder predictions in CASP6.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Assessment of disorder predictions in CASP7.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Analysis of ordered and disordered protein complexes reveals structural features discriminating between stable and unstable monomers

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Mining alpha-helix-forming molecular recognition features with cross species sequence alignments

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Coupled folding and binding with alpha-helix-forming molecular recognition elements

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Reduced amino acid alphabet is sufficient to accurately recognize intrinsically disordered protein.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

An iterative method for extracting energy-like quantities from protein structures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.87

Protein disorder prediction at multiple levels of sensitivity and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.87

Viral RNA-polymerases -- a predicted 2'-O-ribose methyltransferase domain shared by all Mononegavirales

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Structural disorder and modular organization in Paramyxovirinae N and P.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

VaZyMolO: a tool to define and classify modularity in viral proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Multiple sequence alignment with hierarchical clustering

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

POODLE-L: a two-level SVM prediction system for reliably predicting long disordered regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.87

Natively unstructured regions in proteins identified from contact predictions

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Predicting mostly disordered proteins by using structure-unknown protein data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.87

Using Bayesian multinomial classifier to predict whether a given protein sequence is intrinsically disordered.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

OnD-CRF: predicting order and disorder in proteins using [corrected] conditional random fields

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

CDF it all: consensus prediction of intrinsically disordered proteins based on various cumulative distribution functions

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Prediction of disordered regions in proteins based on the meta approach.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Improved disorder prediction by combination of orthogonal approaches

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

MeDor: a metaserver for predicting protein disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

New methods for accurate prediction of protein secondary structure

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

StrBioLib: a Java library for development of custom computational structural biology applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.87

Predicting intrinsic disorder from amino acid sequence

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

A combined transmembrane topology and signal peptide prediction method

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Flavors of protein disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Intrinsically Disordered Proteins in Human Diseases: Introducing the D 2 Concept

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Assessing protein disorder and induced folding

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

NORSp: Predictions of long regions without regular secondary structure

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Wiggle-predicting functionally flexible regions from primary sequence

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Composition Profiler: a tool for discovery and visualization of amino acid composition differences

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Natively unstructured loops differ from other loops

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

TOP-IDP-scale: a new amino acid scale measuring propensity for intrinsic disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Identification of Intrinsically Unstructured Proteins using hierarchical classifier.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Predicting disordered regions in proteins using the profiles of amino acid indices

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Large-scale prediction of long disordered regions in proteins using random forests

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Intrinsic Structural Disorder of DF31, aDrosophilaProtein of Chromatin Decondensation and Remodeling Activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.87

Evaluation of disorder predictions in CASP5

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

Hsien Wu and the First Theory of Protein Denaturation (1931)

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.87

7 January 2021

The unfoldomics decade: an update on intrinsically disordered proteins.

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7 January 2021

Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners

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A conformational study of human spectrin

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Calmodulin signaling: analysis and prediction of a disorder-dependent molecular recognition

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https://api.crossref.org/works/10.1038%2FCR.2009.87

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Optimizing long intrinsic disorder predictors with protein evolutionary information

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https://api.crossref.org/works/10.1038%2FCR.2009.87

7 January 2021

Biochemistry. Controlled chaos

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https://api.crossref.org/works/10.1038%2FCR.2009.87

7 January 2021

POODLE-S: web application for predicting protein disorder by using physicochemical features and reduced amino acid set of a position-specific scoring matrix

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https://api.crossref.org/works/10.1038%2FCR.2009.87

7 January 2021

Intrinsic disorder prediction from the analysis of multiple protein fold recognition models

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https://api.crossref.org/works/10.1038%2FCR.2009.87

7 January 2021

Prediction of unfolded segments in a protein sequence based on amino acid composition

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https://api.crossref.org/works/10.1038%2FCR.2009.87

7 January 2021

DPROT: prediction of disordered proteins using evolutionary information

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https://api.crossref.org/works/10.1038%2FCR.2009.87

7 January 2021

Identifiers

DOI

10.1038/CR.2009.87

1 reference

21 August 2017

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