The functional role of MnSOD as a biomarker of human diseases and therapeutic potential of a new isoform of a human recombinant MnSOD (Q37552213)

21 August 2017

The functional role of MnSOD as a biomarker of human diseases and therapeutic potential of a new isoform of a human recombinant MnSOD (English)

1 reference

21 August 2017

0 references

3

Patrizia Bonelli

1 reference

21 August 2017

Antonella Borrelli

1

1 reference

21 August 2017

Antonietta Schiattarella

2

1 reference

21 August 2017

Franca Maria Tuccillo

4

1 reference

21 August 2017

Franco Maria Buonaguro

5

1 reference

21 August 2017

Aldo Mancini

6

1 reference

21 August 2017

language of work or name

English

0 references

publication date

6 January 2014

1 reference

BioMed Research International

21 August 2017

1 reference

21 August 2017

2014

1 reference

21 August 2017

476789

1 reference

Creative Commons Attribution 3.0 Unported

21 August 2017

start time

1 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes

23 August 2017

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Mechanism of the peroxidase activity of Cu, Zn superoxide dismutase

23 August 2017

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Overexpression of Mn superoxide dismutase does not increase life span in mice

23 August 2017

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23 August 2017

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Defects of mitochondrial electron transport chain in bipolar disorder: implications for mood-stabilizing treatment

23 August 2017

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Redox-regulated mechanisms in asthma

23 August 2017

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Microcirculation and oxidative stress

23 August 2017

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Regulation of HIF-1alpha stability through S-nitrosylation

23 August 2017

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Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site

23 August 2017

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Protein tyrosine nitration in hydrophilic and hydrophobic environments.

23 August 2017

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Superoxide, peroxynitrite and oxidative/nitrative stress in inflammation

23 August 2017

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ALS: a disease of motor neurons and their nonneuronal neighbors

23 August 2017

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Nitric oxide, a double edged sword in cancer biology: searching for therapeutic opportunities

23 August 2017

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Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stress

23 August 2017

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Manganese superoxide dismutase induces p53-dependent senescence in colorectal cancer cells.

23 August 2017

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Extracellular superoxide dismutase

23 August 2017

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Mechanism of the tumor suppressive effect of MnSOD overexpression

23 August 2017

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Role of superoxide as a signaling molecule.

23 August 2017

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GTPases and reactive oxygen species: switches for killing and signaling

23 August 2017

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The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma.

23 August 2017

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Diabetes, oxidative stress, and antioxidants: a review

23 August 2017

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New aspects on angiotensin-converting enzyme: from gene to disease

23 August 2017

1 reference

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The solution structure of reduced dimeric copper zinc superoxide dismutase. The structural effects of dimerization

23 August 2017

1 reference

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The danger model: a renewed sense of self

23 August 2017

1 reference

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Furin proteolytically processes the heparin-binding region of extracellular superoxide dismutase

23 August 2017

1 reference

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Reactive oxygen generated by Nox1 triggers the angiogenic switch

23 August 2017

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Hypoxia and oxidative stress in breast cancer. Oxidative stress: its effects on the growth, metastatic potential and response to therapy of breast cancer

23 August 2017

1 reference

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Role of reactive oxygen species in apoptosis: implications for cancer therapy.

23 August 2017

1 reference

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Oxidative stress and Alzheimer disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Antioxidant enzymes and human diseases

23 August 2017

1 reference

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The beneficial effect of human recombinant superoxide dismutase on acute and chronic rejection events in recipients of cadaveric renal transplants.

23 August 2017

1 reference

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Protection against oxygen toxicity by intravenous injection of liposome-entrapped catalase and superoxide dismutase

23 August 2017

1 reference

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Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)

23 August 2017

1 reference

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The reduction of cytochrome c by milk xanthine oxidase

23 August 2017

1 reference

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Orgotein: a new antiinflammatory metalloprotein drug evaluation of clinical efficacy and safety in inflammatory conditions of the urinary tract

23 August 2017

1 reference

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Oxygen-dependent mutagenesis in Escherichia coli lacking superoxide dismutase

23 August 2017

1 reference

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Complementary DNA encoding human colon cancer manganese superoxide dismutase and the expression of its gene in human cells

23 August 2017

1 reference

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Oxidative stress and cancer: an overview

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Manganese superoxide dismutase regulation and cancer

6 September 2017

1 reference

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Nanoparticle delivery systems for cancer therapy: advances in clinical and preclinical research.

6 September 2017

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A molecular carrier to transport and deliver cisplatin into endometrial cancer cells

6 September 2017

1 reference

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SOD mimetics: a novel class of androgen receptor inhibitors that suppresses castration-resistant growth of prostate cancer

6 September 2017

1 reference

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Nanoparticles for intracellular-targeted drug delivery

6 September 2017

1 reference

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Targeted drug delivery using immunoconjugates: principles and applications

6 September 2017

1 reference

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Chemotherapy treatment decision making by professionals and older patients with cancer: a narrative review of the literature

6 September 2017

1 reference

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Nanomedicine for cancer: lipid-based nanostructures for drug delivery and monitoring

6 September 2017

1 reference

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Anticancer antioxidant regulatory functions of phytochemicals.

6 September 2017

1 reference

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Anticancer therapy with checkpoint inhibitors: what, where and when?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Update on non-viral delivery methods for cancer therapy: possibilities of a drug delivery system with anticancer activities beyond delivery as a new therapeutic tool

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Manganese superoxide dismutase gene dosage affects chromosomal instability and tumor onset in a mouse model of T cell lymphoma.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Role of superoxide dismutase in cancer: a review

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

The leader peptide of a human rec. MnSOD as molecular carrier which delivers high amounts of Cisplatin into tumor cells inducing a fast apoptosis in vitro

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Expression of antioxidant enzymes in diseases of the human pancreas: another link between chronic pancreatitis and pancreatic cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Generation of antioxidant adenovirus gene transfer vectors encoding CuZnSOD, MnSOD, and catalase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

A recombinant MnSOD is radioprotective for normal cells and radiosensitizing for tumor cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Biophysical and biochemical characterization of a liposarcoma-derived recombinant MnSOD protein acting as an anticancer agent

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Extracellular redox state regulates features associated with prostate cancer cell invasion

14 September 2017

1 reference

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Human manganese superoxide dismutase suppresses HER2/neu-mediated breast cancer malignancy

14 September 2017

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Enzymatic activity is necessary for the tumor-suppressive effects of MnSOD.

14 September 2017

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Tumor suppressive activity of a variant isoform of manganese superoxide dismutase released by a human liposarcoma cell line

14 September 2017

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Tumor suppressive effects of MnSOD overexpression may involve imbalance in peroxide generation versus peroxide removal

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Potent anti-tumor effects of an active site mutant of human manganese-superoxide dismutase. Evolutionary conservation of product inhibition

14 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Suppression of the malignant phenotype in human pancreatic cancer cells by the overexpression of manganese superoxide dismutase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

v-Ha-ras mitogenic signaling through superoxide and derived reactive oxygen species

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Embryonic apoptosis-inducing proteins exhibited anticancer activity in vitro and in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Decreased pulmonary radiation resistance of manganese superoxide dismutase (MnSOD)-deficient mice is corrected by human manganese superoxide dismutase-Plasmid/Liposome (SOD2-PL) intratracheal gene therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

A conditioned medium from a human liposarcoma-derived cell line induces p53-dependent apoptosis in several tumor cell lines.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Superoxide generation in v-Ha-ras-transduced human keratinocyte HaCaT cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Targeted gene transfer system using a streptavidin-transforming growth factor-alpha chimeric protein.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Establishment and growth regulation of a novel ovarian cancer cell line from a poorly-differentiated adenocarcinoma: proposal for a new treatment.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Complexes of 2-hydroxyacetophenone semicarbazones: A novel series of superoxide dismutase mimetics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Overexpression of manganese superoxide dismutase in DU145 human prostate carcinoma cells has multiple effects on cell phenotype

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Transfection and expression of MnSOD cDNA decreases tumor malignancy of human oral squamous carcinoma SCC-25 cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Defective gene expression of MnSOD in cancer cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Electron-spin-resonance evidence for enzymic reduction of oxygen to a free radical, the superoxide ion.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Isolation of superoxide dismutase mutants in Escherichia coli: is superoxide dismutase necessary for aerobic life?

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

SOD2: a new type of tumor-suppressor gene?

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Sublocalization of the gene encoding manganese superoxide dismutase (MnSOD/SOD2) to 6q25 by fluorescence in situ hybridization and somatic cell hybrid mapping

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Effect of a recombinant manganese superoxide dismutase on prevention of contrast-induced acute kidney injury.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

A new recombinant MnSOD prevents the cyclosporine A-induced renal impairment.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Recombinant human manganese superoxide dismutase reduces liver fibrosis and portal pressure in CCl4-cirrhotic rats

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Antioxidant activity of β-selenoamines and their capacity to mimic different enzymes.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

A manganese-superoxide dismutase/catalase mimetic extends survival in a mouse model of human prion disease

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Redox-based therapeutics for lung diseases

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

SOD, oxidative stress and human pathologies: a brief history and a future vision.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Inhibition of cell growth by overexpression of manganese superoxide dismutase (MnSOD) in human pancreatic carcinoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Intraoral manganese superoxide dismutase-plasmid/liposome (MnSOD-PL) radioprotective gene therapy decreases ionizing irradiation-induced murine mucosal cell cycling and apoptosis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Down-regulation of DNA repair in human CD34(+) progenitor cells corresponds to increased drug sensitivity and apoptotic response

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Extracellular superoxide dismutase overexpression protects against aging-induced cognitive impairment in mice.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Manganese superoxide dismutase deficiency enhances cell turnover via tumor promoter-induced alterations in AP-1 and p53-mediated pathways in a skin cancer model.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

EC-SOD and the response to inflammatory reactions and aging in mouse lung

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Superoxide production and expression of nox family proteins in human atherosclerosis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Differential expression of manganese superoxide dismutase and catalase in lung cancer

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Overexpression of manganese superoxide dismutase suppresses tumor formation by modulation of activator protein-1 signaling in a multistage skin carcinogenesis model.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Superoxide dismutases in gastric and esophageal cancer and the prognostic impact in gastric cancer.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Identification and functional characterization of the bovine manganous superoxide dismutase promoter.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Liposome-mediated augmentation of superoxide dismutase in endothelial cells prevents oxygen injury.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913005

Synthesis and anti-inflammatory activity of a chimeric recombinant superoxide dismutase: SOD2/3

1 September 2018

1 reference

12 December 2020

Overexpression of manganese superoxide dismutase mRNA may correlate with aggressiveness in gastric and colorectal adenocarcinomas

1 reference

12 December 2020

MnSOD expression is increased in metastatic gastric cancer

1 reference

12 December 2020

Synthesis of a superoxide dismutase derivative that circulates bound to albumin and accumulates in tissues whose pH is decreased

1 reference

12 December 2020

Expression of manganese superoxide dismutase in esophageal and gastric cancers

1 reference

12 December 2020

The transcriptional repression of the human Cu/Zn superoxide dismutase(sod1) gene by the anticancer drug, mitomycin C(MMC)

1 reference

12 December 2020

Superoxide dismutase treatment of 2 cases of radiation-induced sclerosis

1 reference

12 December 2020

MnSOD expression is less frequent in tumour cells of invasive breast carcinomas than in in situ carcinomas or non-neoplastic breast epithelial cells

1 reference

12 December 2020

Cu/Zn superoxide dismutase modulates phenotypic changes in cultured fibroblasts from human skin with chronic radiotherapy damage

1 reference

12 December 2020

Construction of a graphene oxide based noncovalent multiple nanosupramolecular assembly as a scaffold for drug delivery

1 reference

12 December 2020

Manganese superoxide dismutase overexpression inhibits the growth of androgen-independent prostate cancer cells

1 reference

12 December 2020

Identifiers

DOI

10.1155/2014/476789

1 reference

21 August 2017

1 reference

21 August 2017

1 reference