CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter. (Q37564798)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27356740%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter (English)

1 reference

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17 March 2020

0 references

3

1 reference

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17 March 2020

Joseph Irudayaraj

5

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17 March 2020

author name string

Samrat Roy Choudhury

1

1 reference

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17 March 2020

Yi Cui

2

1 reference

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17 March 2020

Barbara Stefanska

4

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17 March 2020

language of work or name

English

0 references

publication date

1 July 2016

1 reference

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17 March 2020

1 reference

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17 March 2020

volume

7

1 reference

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17 March 2020

issue

29

1 reference

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17 March 2020

page(s)

46545-46556

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Selective increase in subtelomeric DNA methylation: an epigenetic biomarker for malignant glioma

17 March 2020

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23 August 2017

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Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation

23 August 2017

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DNA demethylation dynamics

23 August 2017

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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

23 August 2017

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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

23 August 2017

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Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain

23 August 2017

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Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

23 August 2017

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

23 August 2017

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23 August 2017

Epigenetics in cancer

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Epigenetic events in mammalian germ-cell development: reprogramming and beyond

23 August 2017

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UHRF1 plays a role in maintaining DNA methylation in mammalian cells

23 August 2017

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Epigenetic reprogramming in mammals

23 August 2017

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23 August 2017

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Epigenetics in human disease and prospects for epigenetic therapy

23 August 2017

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Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

23 August 2017

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Cancer Incidence in BRCA1 mutation carriers

23 August 2017

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A gene hypermethylation profile of human cancer

23 August 2017

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Active demethylation of the paternal genome in the mouse zygote

23 August 2017

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Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors

23 August 2017

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23 August 2017

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Inhibition of protein phosphatase 2A sensitizes pancreatic cancer to chemotherapy by increasing drug perfusion via HIF-1α-VEGF mediated angiogenesis

6 September 2017

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Uncovering the role of 5-hydroxymethylcytosine in the epigenome

6 September 2017

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Sp1 binding is inhibited by (m)Cp(m)CpG methylation.

6 September 2017

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MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development

6 September 2017

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UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer

6 September 2017

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CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors.

14 September 2017

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The tumor suppressor activity induced by adenovirus-mediated BRCA1 overexpression is not restricted to breast cancers

14 September 2017

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BRCA1 as a potential human prostate tumor suppressor: modulation of proliferation, damage responses and expression of cell regulatory proteins

14 September 2017

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Induction of apoptosis by the tumor suppressor protein BRCA1.

28 September 2017

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The role of DNA methylation in cancer genetic and epigenetics

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5216816

TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5216816

Egr-1 regulates the transcription of the BRCA1 gene by etoposide

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5216816

Genistein increases gene expression by demethylation of WNT5a promoter in colon cancer cell line SW1116.

25 June 2018

1 reference

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BRCA1 promoter region hypermethylation in ovarian carcinoma: a population-based study

25 June 2018

1 reference

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Growth retardation and tumour inhibition by BRCA1.

1 September 2018

1 reference

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Epigenetic reprogramming in mouse primordial germ cells

1 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27356740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mitochondria and the death of oocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27356740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Definition of the landscape of promoter DNA hypomethylation in liver cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27356740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.10234

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27356740%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27356740%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

PubMed publication ID

27356740

1 reference