CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors. (Q39847579)

15 September 2017

title

CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors (English)

1 reference

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11 May 2020

1 reference

8

Olufunmilayo I Olopade

2 references

15 September 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6697119&resulttype=core&format=json

11 May 2020

author name string

Jinhua Xu

1

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11 May 2020

Dezheng Huo

2

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11 May 2020

Yinghua Chen

3

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11 May 2020

Chika Nwachukwu

4

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11 May 2020

Cindy Collins

5

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11 May 2020

Janelle Rowell

6

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11 May 2020

Dennis J Slamon

7

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11 May 2020

language of work or name

English

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publication date

23 May 2009

1 reference

Breast Cancer Research and Treatment

15 September 2017

published in

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11 May 2020

volume

120

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11 May 2020

issue

3

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11 May 2020

page(s)

593-601

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https://scigraph.springernature.com/pub.10.1007/s10549-009-0422-1

11 May 2020

exact match

0 references

cites work

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

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12 December 2020

Regulation of BRCA1 expression by the Rb-E2F pathway.

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Low-dose 5-aza-2'-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: a multicenter phase II study in elderly patients

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Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors

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CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

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12 December 2020

Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens

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12 December 2020

Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer

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CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locus

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Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation.

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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Worms gang up on bacteria

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BRCA1 methylation: a significant role in tumour development?

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12 December 2020

Reduced Brca1 protein expression in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced rat mammary carcinomas

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Regulation of BRCA1 expression and its relationship to sporadic breast cancer

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Inhibition of DNA methylation and reactivation of silenced genes by zebularine

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E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9.

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Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies

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Gene silencing in cancer in association with promoter hypermethylation

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Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells

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DNA binding sites for putative methylation boundaries in the unmethylated region of the BRCA1 promoter.

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Preferential response of cancer cells to zebularine.

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Zebularine: a new drug for epigenetic therapy

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BRCA1 promoter methylation in sporadic breast tumors: relationship to gene expression profiles

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Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylate

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Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.

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BRCA1 promoter methylation in sporadic breast cancer is associated with reduced BRCA1 copy number and chromosome 17 aneusomy

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Hypoxia-induced down-regulation of BRCA1 expression by E2Fs.

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Epigenetic therapy of cancer: past, present and future

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Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.

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CTCF-dependent chromatin insulator is linked to epigenetic remodeling

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The epigenomics of cancer

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12 December 2020

Estrogen receptor alpha, BRCA1, and FANCF promoter methylation occur in distinct subsets of sporadic breast cancers

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12 December 2020

High-performance Liquid Chromatographic Analysis of Chemical Stability of 5-aza-2′-Deoxycytidine

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12 December 2020

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

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12 December 2020

BRCA1 mutations in primary breast and ovarian carcinomas

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12 December 2020

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

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12 December 2020

Frequency of breast cancer attributable to BRCA1 in a population-based series of American women

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12 December 2020

Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells

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12 December 2020

Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas

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12 December 2020

The fundamental role of epigenetic events in cancer

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12 December 2020

10.1007/S10549-009-0422-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6697119&resulttype=core&format=json

11 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6697119&resulttype=core&format=json

11 May 2020

1 reference