egl-1: a key activator of apoptotic cell death in C. elegans (Q37566224)

21 August 2017

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title

egl-1: a key activator of apoptotic cell death in C. elegans (English)

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21 August 2017

Caenorhabditis elegans

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apoptotic process

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author name string

R Nehme

series ordinal

1

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PubMed ID

19641505

21 August 2017

B Conradt

series ordinal

2

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PubMed ID

19641505

21 August 2017

language of work or name

English

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publication date

1 December 2008

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21 August 2017

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21 August 2017

27 Suppl 1

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21 August 2017

S30-40

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https://scigraph.springernature.com/pub.10.1038/onc.2009.41

21 August 2017

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cites work

Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death

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https://api.crossref.org/works/10.1038%2FONC.2009.41

Role of CED-4 in the activation of CED-3.

21 January 2018

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Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.41

The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.41

Genome sequence of the nematode C. elegans: a platform for investigating biology

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.41

Caenorhabditis elegans EGL-1 disrupts the interaction of CED-9 with CED-4 and promotes CED-3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics

21 January 2018

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Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance.

21 January 2018

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Mitochondria as the central control point of apoptosis

21 January 2018

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HLH-3 is a C. elegans Achaete/Scute protein required for differentiation of the hermaphrodite-specific motor neurons

21 January 2018

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Genetic control of programmed cell death in the nematode C. elegans.

21 January 2018

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The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

21 January 2018

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The PLZF-like protein TRA-4 cooperates with the Gli-like transcription factor TRA-1 to promote female development in C. elegans.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.41

Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals

21 January 2018

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Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K

21 January 2018

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Some C. elegans class B synthetic multivulva proteins encode a conserved LIN-35 Rb-containing complex distinct from a NuRD-like complex

21 January 2018

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Control of apoptosis by asymmetric cell division

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.41

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

21 January 2018

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Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2.

21 January 2018

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C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

21 January 2018

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Mitochondrial dynamics: to be in good shape to survive

21 January 2018

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Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis

21 January 2018

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21 January 2018

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Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia

21 January 2018

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Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.41

Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.41

harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.41

SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein

21 January 2018

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Direct physical interaction between the Caenorhabditis elegans 'death proteins' CED-3 and CED-4.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.41

DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.41

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.41

Role of Bax and Bak in mitochondrial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

BH3-only proteins in cell death initiation, malignant disease and anticancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Chromatin regulation and sex determination in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Barhl1 regulates migration and survival of cerebellar granule cells by controlling expression of the neurotrophin-3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Barhl1 is required for maintenance of a large population of neurons in the zonal layer of the superior colliculus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Direct regulation of egl-1 and of programmed cell death by the Hox protein MAB-5 and by CEH-20, a C. elegans homolog of Pbx1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Timing of the onset of a developmental cell death is controlled by transcriptional induction of the C. elegans ced-3 caspase-encoding gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

The pro-apoptotic activity of a vertebrate Bar-like homeobox gene plays a key role in patterning the Xenopus neural plate by limiting the number of chordin- and shh-expressing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Pax2/5/8 proteins promote cell survival in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Control of sex-specific apoptosis in C. elegans by the BarH homeodomain protein CEH-30 and the transcriptional repressor UNC-37/Groucho

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

The p53 family and programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Gli and hedgehog in cancer: tumours, embryos and stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

The C. elegans protein CEH-30 protects male-specific neurons from apoptosis independently of the Bcl-2 homolog CED-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Caenorhabditis elegans CED-4 stimulates CED-3 processing and CED-3-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Interaction between the C. elegans cell-death regulators CED-9 and CED-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

The nucleotide excision repair pathway is required for UV-C-induced apoptosis in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Requirement for caspase-8 in NF-kappaB activation by antigen receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Mitochondrial dynamics and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

The embryonic cell lineage of the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

The Snail-like CES-1 protein of C. elegans can block the expression of the BH3-only cell-death activator gene egl-1 by antagonizing the function of bHLH proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

BID: a novel BH3 domain-only death agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Interaction and regulation of the Caenorhabditis elegans death protease CED-3 by CED-4 and CED-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Interaction and regulation of subcellular localization of CED-4 by CED-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

The BCL-2 protein family: opposing activities that mediate cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Zinc fingers in sex determination: only one of the two C. elegans Tra-1 proteins binds DNA in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

A gene involved in the development of the posterior body region of C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

The role of mitochondria in apoptosis induction in Caenorhabditis elegans: more than just innocent bystanders?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

C. elegans orthologs of components of the RB tumor suppressor complex have distinct pro-apoptotic functions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.41

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.41

1 reference

21 August 2017

1 reference

PubMed ID

19641505