TNF-α blockade induces IL-10 expression in human CD4+ T cells (Q37570592)

21 August 2017

TNF-α blockade induces IL-10 expression in human CD4+ T cells (English)

1 reference

21 August 2017

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Ceri A Roberts

6

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Nicola J Gullick

Nicola J Gullick

4

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Urmas Roostalu

Urmas Roostalu

2

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Frederic Geissmann

Frederic Geissmann

11

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Leonie S. Taams

Leonie S Taams

13

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Andrew P Cope

Andrew P Cope

10

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author name string

Hayley G Evans

1

1 reference

21 August 2017

Gina J Walter

3

1 reference

21 August 2017

Klaus S Frederiksen

5

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21 August 2017

Jonathan Sumner

7

1 reference

21 August 2017

Dominique L Baeten

8

1 reference

21 August 2017

Jens G Gerwien

9

1 reference

21 August 2017

Bruce W Kirkham

12

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21 August 2017

language of work or name

English

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publication date

1 January 2014

1 reference

21 August 2017

Nature Communications

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21 August 2017

5

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21 August 2017

3199

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https://scigraph.springernature.com/pub.10.1038/ncomms4199

21 August 2017

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cites work

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Aiolos promotes TH17 differentiation by directly silencing Il2 expression

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Increasing levels of circulating Th17 cells and interleukin-17 in rheumatoid arthritis patients with an inadequate response to anti-TNF-α therapy

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Linking power Doppler ultrasound to the presence of th17 cells in the rheumatoid arthritis joint

23 August 2017

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23 August 2017

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Ikaros is a regulator of Il10 expression in CD4+ T cells

23 August 2017

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23 August 2017

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c-Maf regulates IL-10 expression during Th17 polarization

23 August 2017

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In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses

23 August 2017

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The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

23 August 2017

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TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

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23 August 2017

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Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells

23 August 2017

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Phenotypic and functional features of human Th17 cells

23 August 2017

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Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

23 August 2017

1 reference

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Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: a two-year prospective study (the DAMAGE study cohort).

23 August 2017

1 reference

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TNF downmodulates the function of human CD4+CD25hi T-regulatory cells

23 August 2017

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23 August 2017

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23 August 2017

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Aiolos and Ikaros: regulators of lymphocyte development, homeostasis and lymphoproliferation

23 August 2017

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Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli

23 August 2017

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23 August 2017

https://api.crossref.org/works/10.1038%2FNCOMMS4199

7 January 2021

inferred from DOI database lookup

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Aiolos regulates B cell activation and maturation to effector state

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex; reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Effect of IL-17A blockade with secukinumab in autoimmune diseases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

The Th1 life cycle: molecular control of IFN-γ to IL-10 switching

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Role of Stat3 in lipopolysaccharide-induced IL-10 gene expression.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Incomplete response of inflammatory arthritis to TNFα blockade is associated with the Th17 pathway.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Increased IL-17 production by peripheral T helper cells after tumour necrosis factor blockade in rheumatoid arthritis is accompanied by inhibition of migration-associated chemokine receptor expression.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

cAMP regulates IL-10 production by normal human T lymphocytes at multiple levels: a potential role for MEF2.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Antagonistic interactions between Ikaros and the chromatin remodeler Mi-2beta determine silencer activity and Cd4 gene expression

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918582

Anti-TNF therapy in patients with rheumatoid arthritis decreases Th1 and Th17 cell populations and expands IFN-γ-producing NK cell and regulatory T cell subsets

1 September 2018

1 reference

12 December 2020

Efficacy and safety of adalimumab for the treatment of peripheral arthritis in spondyloarthritis patients without ankylosing spondylitis or psoriatic arthritis

1 reference

12 December 2020

Induction of an anti-inflammatory cytokine, IL-10, in dendritic cells after toll-like receptor signaling

1 reference

12 December 2020

Role of Th17 cells in human autoimmune arthritis

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS4199

1 reference

release_yrwgb5s7xfe2lpznxpgayy4yma

21 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yrwgb5s7xfe2lpznxpgayy4yma

24 November 2022

mapped directly with Wikidata item

1 reference

21 August 2017

1 reference