ETS gene fusions in prostate cancer (Q37573395)

21 August 2017

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title

ETS gene fusions in prostate cancer (English)

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21 August 2017

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Jeremy P Clark

1

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21 August 2017

Colin S Cooper

series ordinal

2

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21 August 2017

language of work or name

English

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publication date

1 August 2009

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21 August 2017

Nature Reviews Urology

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21 August 2017

6

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21 August 2017

8

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21 August 2017

429-439

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https://scigraph.springernature.com/pub.10.1038/nrurol.2009.127

21 August 2017

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cites work

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Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts

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Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains

31 March 2020

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The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells

31 March 2020

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Expression and function of Ets transcription factors in mammalian development: a regulatory network

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Transcription factor ERG variants and functional diversification of chondrocytes during limb long bone development

31 March 2020

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Ets factors and regulation of the extracellular matrix

31 March 2020

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ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons

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ETV6: a versatile player in leukemogenesis.

31 March 2020

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ETV6-NTRK3--Trk-ing the primary event in human secretory breast cancer

31 March 2020

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A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma

31 March 2020

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Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

31 March 2020

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TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort.

31 March 2020

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Genomic profiling reveals alternative genetic pathways of prostate tumorigenesis

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma

31 March 2020

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TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer

31 March 2020

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Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model.

31 March 2020

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TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming

31 March 2020

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Multiple genomic alterations on 21q22 predict various TMPRSS2/ERG fusion transcripts in human prostate cancers

31 March 2020

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Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer

31 March 2020

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Genome-Wide Linkage Analysis of TMPRSS2-ERG Fusion in Familial Prostate Cancer

31 March 2020

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Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

31 March 2020

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Two unique novel prostate-specific and androgen-regulated fusion partners of ETV4 in prostate cancer

31 March 2020

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Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer

31 March 2020

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A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer

31 March 2020

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Gene fusions between TMPRSS2 and ETS family genes in prostate cancer: frequency and transcript variant analysis by RT-PCR and FISH on paraffin-embedded tissues

31 March 2020

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Complex patterns of ETS gene alteration arise during cancer development in the human prostate

31 March 2020

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Confirmation of the high frequency of the TMPRSS2/ERG fusion gene in prostate cancer.

31 March 2020

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Diversity of TMPRSS2-ERG fusion transcripts in the human prostate

31 March 2020

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Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 gene fusions in prostate cancer.

31 March 2020

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Detection of TMPRSS2-ERG translocations in human prostate cancer by expression profiling using GeneChip Human Exon 1.0 ST arrays

31 March 2020

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Delineation of TMPRSS2-ERG splice variants in prostate cancer

31 March 2020

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TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

TMPRSS2:ETV4 gene fusions define a third molecular subtype of prostate cancer

31 March 2020

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Truncated ETV1, fused to novel tissue-specific genes, and full-length ETV1 in prostate cancer.

31 March 2020

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ETV1 is a novel androgen receptor-regulated gene that mediates prostate cancer cell invasion.

31 March 2020

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A causal role for ERG in neoplastic transformation of prostate epithelium.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Role of the TMPRSS2-ERG gene fusion in prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

TMPRSS2-ERG Fusion Prostate Cancer: An Early Molecular Event Associated With Invasion

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Heterogeneity of TMPRSS2 gene rearrangements in multifocal prostate adenocarcinoma: molecular evidence for an independent group of diseases

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Detection of TMPRSS2:ERG fusion gene in circulating prostate cancer cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

New androgen receptor genomic targets show an interaction with the ETS1 transcription factor.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

The evolving role of oestrogens and their receptors in the development and progression of prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Toremifene for the prevention of prostate cancer in men with high grade prostatic intraepithelial neoplasia: results of a double-blind, placebo controlled, phase IIB clinical trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

TMPRSS2:ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Three-color FISH analysis of TMPRSS2/ERG fusions in prostate cancer indicates that genomic microdeletion of chromosome 21 is associated with rearrangement

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Mapping of TMPRSS2-ERG fusions in the context of multi-focal prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Expression of the TMPRSS2:ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Frequency of the TMPRSS2:ERG gene fusion is increased in moderate to poorly differentiated prostate cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

The role of SPINK1 in ETS rearrangement-negative prostate cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

ETS gene fusions in prostate cancer: from discovery to daily clinical practice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

ETS transcription factors: possible targets for cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

The Myc oncoprotein as a therapeutic target for human cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Progression of prostate cancer: multiple pathways to androgen independence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2009.127

Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19657377

12 December 2020

inferred from PubMed ID database lookup

New human erg isoforms generated by alternative splicing are transcriptional activators

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19657377

12 December 2020

inferred from PubMed ID database lookup

Molecular genetic analyses of the TMPRSS2-ERG and TMPRSS2-ETV1 gene fusions in 50 cases of prostate cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19657377

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NRUROL.2009.127

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Dimensions Publication ID

21 August 2017

1030944708

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Fatcat ID

release_b44dpdr7uvdrtcmmtz2bcj343q

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Fatcat

https://api.fatcat.wiki/v0/release/b44dpdr7uvdrtcmmtz2bcj343q

24 November 2022

mapped directly with Wikidata item

1 reference