Senescence and p130/Rbl2: a new beginning to the end. (Q37577336)

21 August 2017

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title

Senescence and p130/Rbl2: a new beginning to the end. (English)

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21 August 2017

4

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Francesco Paolo Fiorentino

21 August 2017

object named as

Francesco P Fiorentino

series ordinal

1

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Marcella Macaluso

series ordinal

3

object named as

Marcella Macaluso

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21 August 2017

Catherine E Symonds

2

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21 August 2017

publication date

11 August 2009

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21 August 2017

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21 August 2017

volume

19

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21 August 2017

issue

9

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21 August 2017

page(s)

1044-1051

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THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

21 August 2017

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Switching and signaling at the telomere

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Cooperation between p53 and p130(Rb2) in induction of cellular senescence

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

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Unexpected pieces to the senescence puzzle

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Reversal of human cellular senescence: roles of the p53 and p16 pathways

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Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

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Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

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Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein

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Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

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Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

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Hypersensitivity to chromium-induced DNA damage correlates with constitutive deregulation of upstream p53 kinases in p21-/- HCT116 colon cancer cells

21 January 2018

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p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.

21 January 2018

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The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

21 January 2018

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Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes

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Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

21 January 2018

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DNA methyltransferases control telomere length and telomere recombination in mammalian cells

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A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

21 January 2018

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p21Waf1/Cip1 plays a critical role in modulating senescence through changes of DNA methylation

21 January 2018

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DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle withdrawal

21 January 2018

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21 January 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

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Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases

21 January 2018

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Distinct roles for p107 and p130 in Rb-independent cellular senescence

21 January 2018

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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

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G1 phase progression: cycling on cue

21 January 2018

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INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence

21 January 2018

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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

21 January 2018

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A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status

21 January 2018

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A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

Loss of linker histone H1 in cellular senescence

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

Rb targets histone H3 methylation and HP1 to promoters

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Definition of pRB- and p53-dependent and -independent steps in HIRA/ASF1a-mediated formation of senescence-associated heterochromatin foci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Cellular senescence and chromatin structure

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

ROS as a tumour suppressor?

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

Regulation of dihydrofolate reductase gene expression and E2F components in human diploid fibroblasts during growth and senescence

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

The retinoblastoma gene family: cousins with overlapping interests

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

Replicative senescence, aging and growth-regulatory transcription factors

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

7 January 2021

Inducing cellular senescence using defined genetic elements

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https://api.crossref.org/works/10.1038%2FCR.2009.96

7 January 2021

p53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts

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https://api.crossref.org/works/10.1038%2FCR.2009.96

7 January 2021

Comparison of global DNA methylation profiles in replicative versus premature senescence

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https://api.crossref.org/works/10.1038%2FCR.2009.96

7 January 2021

Identifiers

DOI

10.1038/CR.2009.96

1 reference

21 August 2017

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