Vitamin D and calcium insufficiency-related chronic diseases: molecular and cellular pathophysiology (Q37590681)

21 August 2017

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title

Vitamin D and calcium insufficiency-related chronic diseases: molecular and cellular pathophysiology (English)

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21 August 2017

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M Peterlik

1

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PubMed ID

19724293

21 August 2017

H S Cross

series ordinal

2

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21 August 2017

2 September 2009

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European Journal of Clinical Nutrition

21 August 2017

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21 August 2017

63

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21 August 2017

1377-1386

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21 August 2017

12

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https://scigraph.springernature.com/pub.10.1038/ejcn.2009.105

21 August 2017

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cites work

Phosphatidylinositol 3-kinase-dependent, MEK- independent proliferation in response to CaR activation

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

Differential regulation of vitamin D receptor and its ligand in human monocyte-derived dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

IFN-gamma- and TNF-independent vitamin D-inducible human suppression of mycobacteria: the role of cathelicidin LL-37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

Finding consensus in the dietary calcium-blood pressure debate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

IL-10 signaling is essential for 1,25-dihydroxyvitamin D3-mediated inhibition of experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Serum calcium and breast cancer risk: results from a prospective cohort study of 7,847 women

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Modulation of CYP27B1 and CYP24 mRNA expression in bone is independent of circulating 1,25(OH)2D3 levels.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Capacity of a low calcium diet to induce the renal vitamin D 1a-hydroxylase is decreased in adult rats

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Metabolism of vitamin D3 in human osteoblasts: evidence for autocrine and paracrine activities of 1 alpha,25-dihydroxyvitamin D3.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Plasma 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D and Risk of Breast Cancer

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Vitamin D and Calcium Intakes from Food or Supplements and Mammographic Breast Density

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Need for additional calcium to reduce the risk of hip fracture with vitamin d supplementation: evidence from a comparative metaanalysis of randomized controlled trials

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Relation of calcium, vitamin D, and dairy food intake to ischemic heart disease mortality among postmenopausal women

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

New insights in bone biology: unmasking skeletal effects of the extracellular calcium-sensing receptor.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Human calcium-sensing receptor gene. Vitamin D response elements in promoters P1 and P2 confer transcriptional responsiveness to 1,25-dihydroxyvitamin D.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Extracellular calcium-sensing receptor is expressed in rat hepatocytes. coupling to intracellular calcium mobilization and stimulation of bile flow

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Calcium signalling and cancer cell growth.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

The extracellular calcium-sensing receptor (CaSR) is a critical modulator of skeletal development

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Vitamin D3 and calcium to prevent hip fractures in elderly women

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Prevalence of vitamin D insufficiency in an adult normal population

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Dairy foods, calcium, and colorectal cancer: a pooled analysis of 10 cohort studies

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Calcium-sensing receptor expression in human adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Mechanisms implicated in the growth regulatory effects of vitamin D in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Regulation of the colonic vitamin D system for prevention of tumor progression: an update.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Vitamin D metabolism in human colon adenocarcinoma-derived Caco-2 cells: expression of 25-hydroxyvitamin D3-1alpha-hydroxylase activity and regulation of side-chain metabolism

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Vitamin D signalling pathways in cancer: potential for anticancer therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Genetic variation in calcium-sensing receptor and risk for colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Physiological changes in extracellular calcium concentration directly control osteoblast function in the absence of calciotropic hormones

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Calcium-sensing receptor stimulation induces nonselective cation channel activation in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

1,25-Dihydroxyvitamin D inhibits lipopolysaccharide-induced immune activation in human endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Distribution of the vitamin D receptor and 1 alpha-hydroxylase in human brain

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Vitamin D intake and risk of incident hypertension: results from three large prospective cohort studies

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

A Crucial Role for the Vitamin D Receptor in Experimental Inflammatory Bowel Diseases

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Vitamin D insufficiency: disease or no disease?

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Effect of vitamin D and calcium on periodontitis

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Dairy products, dietary calcium and vitamin D intake as risk factors for prostate cancer: a meta-analysis of 26,769 cases from 45 observational studies

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictors

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Optimal vitamin D status attenuates the age-associated increase in systolic blood pressure in white Americans: results from the third National Health and Nutrition Examination Survey

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Colon-specific regulation of vitamin D hydroxylases--a possible approach for tumor prevention.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Molecular and functional characterization of the extracellular calcium-sensing receptor in human colon cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Calcium-dependent c-myc proto-oncogene expression and proliferation of Caco-2 cells: a role for a luminal extracellular calcium-sensing receptor

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Characterization of a vitamin D receptor knockout mouse as a model of colorectal hyperproliferation and DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Calcium and vitamin D supplements reduce tooth loss in the elderly

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Assessment of vitamin D and calcium status in healthy adult Austrians.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

1alpha,25-dihydroxyvitamin D3 downregulates CYP27B1 and induces CYP24A1 in colon cells.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Intakes of calcium and vitamin D and breast cancer risk in women

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Elevated extracellular calcium can prevent apoptosis via the calcium-sensing receptor.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Serum 25-hydroxyvitamin D and hip fracture risk in older U.S. white adults

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Epidermal RANKL controls regulatory T-cell numbers via activation of dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Calcium and calpain as key mediators of apoptosis-like death induced by vitamin D compounds in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Vitamin D and type 1 diabetes mellitus: state of the art.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

In vitro and in vivo analysis of the immune system of vitamin D receptor knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Extracellular calcium-sensing receptor is functionally expressed in human artery

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

1,25-Dihydroxyvitamin D synthesis in rat liver microsomes

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Extracellular calcium elicits a chemokinetic response from monocytes in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Pleiotropic effects of vitamin D on osteoblast gene expression are related to the proliferative and differentiated state of the bone cell phenotype: dependency upon basal levels of gene expression, duration of exposure, and bone matrix competency in

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Vitamin D and calcium deficits predispose for multiple chronic diseases

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Effects of a long-term vitamin D and calcium supplementation on falls and parameters of muscle function in community-dwelling older individuals

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Low serum levels of 25-hydroxyvitamin D predict fatal cancer in patients referred to coronary angiography

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Nutrition and other risk factors for renal cell carcinoma in postmenopausal women

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

25-Hydroxyvitamin D(3) suppresses PTH synthesis and secretion by bovine parathyroid cells.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

The role of the calcium-sensing receptor in cancer

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Megalin-mediated endocytosis of vitamin D binding protein correlates with 25-hydroxycholecalciferol actions in human mammary cells

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

The extracellular calcium-sensing receptor on human beta-cells negatively modulates insulin secretion

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

The calcium-sensing receptor in normal physiology and pathophysiology: a review

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Calcium receptor is functionally expressed in rat neonatal ventricular cardiomyocytes

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

High calcium activates the EGF receptor potentially through the calcium-sensing receptor in Leydig cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Interactions of 1 alpha,25-dihydroxyvitamin D3 with IL-12 and IL-4 on cytokine expression of human T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Both high and low levels of blood vitamin D are associated with a higher prostate cancer risk: A longitudinal, nested case‐control study in the Nordic countries

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Evidence for auto/paracrine actions of vitamin D in bone: 1alpha-hydroxylase expression and activity in human bone cells

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

CaR-mediated COX-2 expression in primary cultured mTAL cells

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Vitamin D deficiency and risk of cardiovascular disease

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Failure of tumor-reactive lymph node cells to kill tumor in the presence of immune-suppressive CD34+ cells can be overcome with vitamin D3 treatment to diminish CD34+ cell levels

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Effects of Vitamin D analogs on gene expression profiling in human coronary artery smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

1,25(OH)2 vitamin D3, and retinoic acid antagonize endothelin-stimulated hypertrophy of neonatal rat cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Mouse osteoblastic cell line (MC3T3-E1) expresses extracellular calcium (Ca2+o)-sensing receptor and its agonists stimulate chemotaxis and proliferation of MC3T3-E1 cells

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Expression of extracellular calcium (Ca2+o)-sensing receptor in human peripheral blood monocytes.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Calcium-sensing receptor in the brain.

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Calcium-sensing receptor activation stimulates parathyroid hormone-related protein secretion in prostate cancer cells: role of epidermal growth factor receptor transactivation

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Calcium and 1 alpha,25-dihydroxyvitamin D3 target the TNF-alpha pathway to suppress experimental inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1038%2FEJCN.2009.105

7 January 2021

Identifiers

DOI

10.1038/EJCN.2009.105

1 reference

21 August 2017

1 reference

PubMed ID

19724293