Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3+ T-regulatory Cell Function and Promotes Antitumor Immunity (Q37604627)

21 August 2017

Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3+ T-regulatory Cell Function and Promotes Antitumor Immunity (English)

1 reference

21 August 2017

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Ulf H Beier

9

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3 June 2020

author name string

Liqing Wang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Suresh Kumar

2

1 reference

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3 June 2020

Feng Wang

4

1 reference

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3 June 2020

Jian Wu

5

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3 June 2020

Kheng Newick

6

1 reference

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3 June 2020

Rongxiang Han

7

1 reference

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3 June 2020

Arabinda Samanta

8

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3 June 2020

Tatiana Akimova

10

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3 June 2020

Tricia R Bhatti

11

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3 June 2020

Benjamin Nicholson

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Mathew P Kodrasov

13

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Saket Agarwal

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

David E Sterner

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Wei Gu

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Joseph Weinstock

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Tauseef R Butt

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Steven M Albelda

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Wayne W Hancock

20

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3 June 2020

publication date

15 October 2016

1 reference

21 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

99-112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

MicroRNA-17 Modulates Regulatory T Cell Function by Targeting Co-regulators of the Foxp3 Transcription Factor

3 June 2020

cites work

1 reference

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FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.

23 August 2017

1 reference

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Two histone/protein acetyltransferases, CBP and p300, are indispensable for Foxp3+ T-regulatory cell development and function

23 August 2017

1 reference

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Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60.

23 August 2017

1 reference

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Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.

23 August 2017

1 reference

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Inhibition of p300 impairs Foxp3⁺ T regulatory cell function and promotes antitumor immunity.

23 August 2017

1 reference

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Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathway

23 August 2017

1 reference

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Lysosome-dependent p300/FOXP3 degradation and limits Treg cell functions and enhances targeted therapy against cancers

23 August 2017

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A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance

23 August 2017

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A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells

23 August 2017

1 reference

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Transcription factor Foxp3 and its protein partners form a complex regulatory network

23 August 2017

1 reference

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Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function

23 August 2017

1 reference

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Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

23 August 2017

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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

23 August 2017

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The blockade of immune checkpoints in cancer immunotherapy

23 August 2017

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Two lysines in the forkhead domain of foxp3 are key to T regulatory cell function

23 August 2017

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Novel cancer immunotherapy agents with survival benefit: recent successes and next steps

23 August 2017

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Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase

23 August 2017

1 reference

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Roles of HAUSP-mediated p53 regulation in central nervous system development

23 August 2017

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Regulatory T cells in tumor immunity

23 August 2017

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Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation

23 August 2017

1 reference

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23 August 2017

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The role of regulatory T cells in cancer

23 August 2017

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Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

23 August 2017

1 reference

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression

23 August 2017

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23 August 2017

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23 August 2017

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A function for interleukin 2 in Foxp3-expressing regulatory T cells

23 August 2017

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Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma

23 August 2017

1 reference

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Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor

23 August 2017

1 reference

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CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

23 August 2017

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Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8

23 August 2017

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Tumour suppression: disruption of HAUSP gene stabilizes p53

23 August 2017

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A dynamic role of HAUSP in the p53-Mdm2 pathway

23 August 2017

1 reference

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23 August 2017

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Histone acetyltransferases

23 August 2017

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23 August 2017

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The multifaceted roles of USP7: new therapeutic opportunities

23 August 2017

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Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47.

6 September 2017

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Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization.

14 September 2017

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IL-2 immunotoxin therapy modulates tumor-associated regulatory T cells and leads to lasting immune-mediated rejection of breast cancers in neu-transgenic mice

14 September 2017

1 reference

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IL-2 intratumoral immunotherapy enhances CD8+ T cells that mediate destruction of tumor cells and tumor-associated vasculature: a novel mechanism for IL-2.

14 September 2017

1 reference

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Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60.

14 September 2017

1 reference

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Reciprocal cross-regulation between RNF41 and USP8 controls cytokine receptor sorting and processing

25 June 2018

1 reference

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Stability of the regulatory T cell lineage in vivo.

25 June 2018

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Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen.

25 June 2018

1 reference

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Anti-PD-1 inhibits Foxp3+ Treg cell conversion and unleashes intratumoural effector T cells thereby enhancing the efficacy of a cancer vaccine in a mouse model.

25 June 2018

1 reference

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Tumour islet Foxp3+ T-cell infiltration predicts poor outcome in nonsmall cell lung cancer.

1 September 2018

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Genome-wide identification of human FOXP3 target genes in natural regulatory T cells

1 September 2018

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Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes

1 September 2018

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Systemic inflammatory response and downmodulation of peripheral CD25+Foxp3+ T-regulatory cells in patients undergoing radiofrequency thermal ablation for lung cancer.

1 September 2018

1 reference

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Deacetylase inhibition promotes the generation and function of regulatory T cells.

1 September 2018

1 reference

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Cycloxygenase-2 inhibition augments the efficacy of a cancer vaccine

1 September 2018

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CTLA-4 blockade: unveiling immune regulation

1 September 2018

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A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

1 September 2018

1 reference

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Tumor infiltrating Foxp3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients

1 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27769803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27769803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Foxp3-dependent programme of regulatory T-cell differentiation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27769803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.EBIOM.2016.10.018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27769803%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference