High glucose induces human endothelial dysfunction through an Axl-dependent mechanism (Q37615975)

21 August 2017

High glucose induces human endothelial dysfunction through an Axl-dependent mechanism (English)

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21 August 2017

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Chien-Hsing Lee

1

1 reference

21 August 2017

Yi-Shing Shieh

2

1 reference

21 August 2017

Fone-Ching Hsiao

3

1 reference

21 August 2017

Feng-Chih Kuo

4

1 reference

21 August 2017

Chih-Yuan Lin

5

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21 August 2017

Chang-Hsun Hsieh

6

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21 August 2017

Yi-Jen Hung

7

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21 August 2017

language of work or name

English

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publication date

26 February 2014

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Cardiovascular Diabetology

21 August 2017

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21 August 2017

13

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21 August 2017

53

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https://scigraph.springernature.com/pub.10.1186/1475-2840-13-53

21 August 2017

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cites work

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α-Lipoic acid attenuates vascular calcification via reversal of mitochondrial function and restoration of Gas6/Axl/Akt survival pathway

23 August 2017

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Plasma protein growth arrest-specific 6 levels are associated with altered glucose tolerance, inflammation, and endothelial dysfunction

23 August 2017

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TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer

23 August 2017

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Gas6-axl receptor signaling is regulated by glucose in vascular smooth muscle cells

23 August 2017

1 reference

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Gas6 and protein S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily.

23 August 2017

1 reference

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Endothelial dysfunction and its role in diabetic vascular disease

23 August 2017

1 reference

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Axl, a receptor tyrosine kinase, mediates flow-induced vascular remodeling

23 August 2017

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The role of gamma-carboxylation in the anti-apoptotic function of gas6

23 August 2017

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Hyperglycemia alters PI3k and Akt signaling and leads to endothelial cell proliferative dysfunction

23 August 2017

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Introduction of hyperglycemia and dyslipidemia in the pathogenesis of diabetic vascular complications

23 August 2017

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Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy

23 August 2017

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Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

23 August 2017

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Molecular understanding of hyperglycemia's adverse effects for diabetic complications

23 August 2017

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Acidification prevents endothelial cell apoptosis by Axl activation

23 August 2017

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Hyperglycemia-induced vasculopathy in the murine conceptus is mediated via reductions of VEGF-A expression and VEGF receptor activation

23 August 2017

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Gas6 induces growth, beta-catenin stabilization, and T-cell factor transcriptional activation in contact-inhibited C57 mammary cells

23 August 2017

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Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study

23 August 2017

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Mechanisms of angiogenesis and arteriogenesis

23 August 2017

1 reference

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Gas6, the ligand of Axl tyrosine kinase receptor, has mitogenic and survival activities for serum starved NIH3T3 fibroblasts

23 August 2017

1 reference

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Growth arrest-specific gene 6 (gas6) and vascular hemostasis

23 August 2017

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Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis

6 September 2017

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Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.

14 September 2017

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Multiple roles for the receptor tyrosine kinase axl in tumor formation

14 September 2017

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Requirement of phosphatidylinositol 3-kinase-dependent pathway and Src for Gas6-Axl mitogenic and survival activities in NIH 3T3 fibroblasts

14 September 2017

1 reference

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GAS6 mediates adhesion of cells expressing the receptor tyrosine kinase Axl.

14 September 2017

1 reference

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Advanced glycation end products evoke endothelial cell damage by stimulating soluble dipeptidyl peptidase-4 production and its interaction with mannose 6-phosphate/insulin-like growth factor II receptor.

28 September 2017

1 reference

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Gas6-mediated survival in NIH3T3 cells activates stress signalling cascade and is independent of Ras.

25 June 2018

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Inhibiting the response to VEGF in diabetes.

25 June 2018

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Plasma concentrations of Gas6 and soluble Axl correlate with disease and predict mortality in patients with critical limb ischemia

1 September 2018

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Axl mediates vascular remodeling induced by deoxycorticosterone acetate-salt hypertension.

1 September 2018

1 reference

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Inhibition of vascular endothelial growth factor receptor 2-mediated endothelial cell activation by Axl tyrosine kinase receptor

1 September 2018

1 reference

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Hydrogen peroxide activates the Gas6-Axl pathway in vascular smooth muscle cells

1 September 2018

1 reference

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Growth arrest-specific gene 6 is involved in glomerular hypertrophy in the early stage of diabetic nephropathy

1 September 2018

1 reference

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Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells

1 September 2018

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12 December 2020

Genetic loss of Gas6 induces plaque stability in experimental atherosclerosis

1 reference

12 December 2020

Increased secretion of Gas6 by smooth muscle cells in human atherosclerotic carotid plaques

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12 December 2020

Vascular Gas6 contributes to thrombogenesis and promotes tissue factor up-regulation after vessel injury in mice

1 reference

12 December 2020

Inhibition of lipid peroxidation restores impaired vascular endothelial growth factor expression and stimulates wound healing and angiogenesis in the genetically diabetic mouse

1 reference

12 December 2020

Effect of diabetes mellitus on formation of coronary collateral vessels

1 reference

12 December 2020

Identifiers

DOI

10.1186/1475-2840-13-53

1 reference

Dimensions Publication ID

21 August 2017

0 references

1 reference

21 August 2017

1 reference