Aberrant glycosylation as biomarker for cancer: focus on CD43. (Q37618865)

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Aberrant glycosylation as biomarker for cancer: focus on CD43 (English)

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Franca Maria Tuccillo

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Camillo Palmieri

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Annamaria de Laurentiis

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Antonella Borrelli

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Pierfrancesco Tassone

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Iris Scala

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Franco Maria Buonaguro

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Giuseppe Scala

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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CD43-mediated signals induce DNA binding activity of AP-1, NF-AT, and NFkappa B transcription factors in human T lymphocytes

23 August 2017

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23 August 2017

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23 August 2017

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Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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T cell activation through the CD43 molecule leads to Vav tyrosine phosphorylation and mitogen-activated protein kinase pathway activation

23 August 2017

1 reference

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Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

23 August 2017

1 reference

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Concentration of an integral membrane protein, CD43 (leukosialin, sialophorin), in the cleavage furrow through the interaction of its cytoplasmic domain with actin-based cytoskeletons

23 August 2017

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Altered glycosylation of leukosialin, CD43, in HIV-1-infected cells of the CEM line

23 August 2017

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CD43, the major sialoglycoprotein of human leukocytes, is proteolytically cleaved from the surface of stimulated lymphocytes and granulocytes

23 August 2017

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Suppression of lung metastasis of B16 mouse melanoma by N-acetylglucosaminyltransferase III gene transfection

23 August 2017

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A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer

23 August 2017

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23 August 2017

Carcinoembryonic antigen

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Leukosialin, a major sialoglycoprotein on human leukocytes as differentiation antigens

23 August 2017

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Molecular characterization of sialophorin (CD43), the lymphocyte surface sialoglycoprotein defective in Wiskott-Aldrich syndrome

23 August 2017

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Characterization of cDNAs encoding human leukosialin and localization of the leukosialin gene to chromosome 16

23 August 2017

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Leukosialin, a major O-glycan-containing sialoglycoprotein defining leukocyte differentiation and malignancy

23 August 2017

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Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

23 August 2017

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Amino acid sequence of human plasma galactoglycoprotein: identity with the extracellular region of CD43 (sialophorin)

23 August 2017

1 reference

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CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1

23 August 2017

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Tn and sialyl-Tn antigens, aberrant O-glycomics as human disease markers

23 August 2017

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Monoclonal antibodies toward different Tn-amino acid backbones display distinct recognition patterns on human cancer cells. Implications for effective immuno-targeting of cancer.

6 September 2017

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Physiological roles of N-acetylglucosaminyltransferase V(GnT-V) in mice

6 September 2017

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CD43 in the nucleus and cytoplasm of lung cancer is a potential therapeutic target

6 September 2017

1 reference

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Carcinoembryonic antigen (CEA) as tumor marker in lung cancer

6 September 2017

1 reference

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A multifunctional shuttling protein nucleolin is a macrophage receptor for apoptotic cells

6 September 2017

1 reference

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Enhanced expression of alpha(1,3)-fucosyltransferase genes correlates with E-selectin-mediated adhesion and metastatic potential of human lung adenocarcinoma cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Carbohydrate recognition systems: functional triads in cell-cell interactions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Characterization of a CD43/leukosialin-mediated pathway for inducing apoptosis in human T-lymphoblastoid cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Differential E-selectin-dependent adhesion efficiency in sublines of a human colon cancer exhibiting distinct metastatic potentials.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Preparation and characterization of monoclonal antibodies directed to the tumor-associated O-linked sialosyl-2----6 alpha-N-acetylgalactosaminyl (sialosyl-Tn) epitope.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

CD43, a molecule with multiple functions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Analysis of differentiation and transformation of cells by lectins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Human tumor antigens Tn and sialyl Tn arise from mutations in Cosmc

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Biological significance of cancer-associated sialyl-Tn antigen: modulation of malignant phenotype in gastric carcinoma cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Shedding and gamma-secretase-mediated intramembrane proteolysis of the mucin-type molecule CD43.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Tumour-expressed CD43 (sialophorin) mediates tumourmesothelial cell adhesion.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Sialylated core 1 based O-linked glycans enhance the growth rate of mammary carcinoma cells in MUC1 transgenic mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

CD43 has a functional NLS, interacts with beta-catenin, and affects gene expression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Relationship between elevated FX expression and increased production of GDP-L-fucose, a common donor substrate for fucosylation in human hepatocellular carcinoma and hepatoma cell lines

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

The leukocyte antigen CD43 is expressed in different cell lines of nonhematopoietic origin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Occurrence of oligosialic acids on integrin alpha 5 subunit and their involvement in cell adhesion to fibronectin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Structural requirements for CD43 function.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Enzymatic basis for sialyl-Tn expression in human colon cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Post-translational fate of a mucin-like leukocyte sialoglycoprotein (CD43) aberrantly expressed in a colon carcinoma cell line.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Mucin glycoproteins in neoplasia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Expression of the leukocyte-associated sialoglycoprotein CD43 by a colon carcinoma cell line

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

CD43 functions as a ligand for E-Selectin on activated T cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

CD43 is a ligand for E-selectin on CLA+ human T cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Immunoreactive T and Tn epitopes in cancer diagnosis, prognosis, and immunotherapy

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Regulatory role of CD43 leukosialin on integrin-mediated T-cell adhesion to endothelial and extracellular matrix ligands and its polar redistribution to a cellular uropod.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Biosynthesis of human sialophorins and analysis of the polypeptide core

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Protein sequence and gene structure for mouse leukosialin (CD43), a T lymphocyte mucin without introns in the coding sequence

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Inhibition of selectin-dependent tumor cell adhesion to endothelial cells and platelets by blocking O-glycosylation of these cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

CD43 processing and nuclear translocation of CD43 cytoplasmic tail are required for cell homeostasis.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Long-term prognostic study of carcinoembryonic antigen (CEA) and carbohydrate antigen 15-3 (CA 15-3) in breast cancer

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Usefulness of CA 125 as a preoperative prognostic marker for transitional cell carcinoma of the bladder

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Estimating the probability of cancer with several tumor markers in patients with colorectal disease

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

The CD43 coreceptor molecule recruits the zeta-chain as part of its signaling pathway

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Tumor cell MUC1 and CD43 are glycosylated differently with sialyl-Lewis a and x epitopes and show variable interactions with E-selectin under physiological flow conditions.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Carbohydrate expression profile of colorectal cancer cells is relevant to metastatic pattern and prognosis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

AFP-L3: a new generation of tumor marker for hepatocellular carcinoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Factors influencing serum CA125II levels in healthy postmenopausal women.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Meaning and therapeutic potential of microbial recognition of host glycoconjugates

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Purification and characterization of a human sialoglycoprotein antigen expressed in immature thymocytes and fetal tissues

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

Prognostic value of preoperative serum levels of CEA, CA 19-9 and CA 72-4 in gastric carcinoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

UN1, a murine monoclonal antibody recognizing a novel human thymic antigen.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

The Roman god Janus: a paradigm for the function of CD43

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3943294

CD43 – One molecule, many tales to recount

2 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2014%2F742831

Increased expression of sialyl Lewisx antigen correlates with poor survival in patients with colorectal carcinoma: clinicopathological and immunohistochemical study

21 January 2018

1 reference

12 December 2020

Preoperative positivity of serum tumor markers is a strong predictor of hematogenous recurrence of gastric cancer

1 reference

12 December 2020

Detection of cd43 (leukosialin) in colon adenoma and adenocarcinoma by novel monoclonal antibodies against its intracellular domain

1 reference

12 December 2020

Expression on blood cells of sialophorin, the surface glycoprotein that is defective in Wiskott-Aldrich syndrome

1 reference

12 December 2020

Expression of Vicia villosa agglutinin (VVA)-binding glycoprotein in primary breast cancer cells in relation to lymphatic metastasis: is atypical MUC1 bearing Tn antigen a receptor of VVA?

1 reference

12 December 2020

Isolation and characterization of leukosialin, a major sialoglycoprotein on human leukocytes

1 reference

12 December 2020

Specific monoclonal antibodies against leukocyte-restricted cell surface molecule CD43 react with nonhematopoietic tumor cells

1 reference

12 December 2020

The prognostic significance of preoperative serum CA 19-9 in patients with resectable gastric carcinoma: comparison with CEA

1 reference

12 December 2020

Thomsen-Friedenreich-related carbohydrate antigens in normal adult human tissues: a systematic and comparative study

1 reference

12 December 2020

Poly-N-acetyllactosaminyl O-glycans attached to leukosialin. The presence of sialyl Le(x) structures in O-glycans

1 reference

12 December 2020

Biosynthetic controls that determine the branching and microheterogeneity of protein-bound oligosaccharides

1 reference

12 December 2020

Carcinoma-associated expression of core 2 beta-1,6-N-acetylglucosaminyltransferase gene in human colorectal cancer: role of O-glycans in tumor progression

1 reference

12 December 2020

Expression of Tn and sialyl-Tn antigens in the neoplastic transformation of uterine cervical epithelial cells

1 reference

12 December 2020

Diagnostic value of CA 19-9 in patients with pancreatic cancer and nonspecific gastrointestinal symptoms

1 reference

12 December 2020

Expression of CD43 on murine and human pluripotent hematopoietic stem cells

1 reference

12 December 2020

Two proteolytic pathways for down-regulation of the barrier molecule CD43 of human neutrophils

1 reference

12 December 2020

Loss of core fucosylation of low-density lipoprotein receptor-related protein-1 impairs its function, leading to the upregulation of serum levels of insulin-like growth factor-binding protein 3 in Fut8-/- mice

1 reference

12 December 2020

Prognostic value of CA 19-9, CEA, CRP, LDH and bilirubin levels in locally advanced and metastatic pancreatic cancer: results from a multicenter, pooled analysis of patients receiving palliative chemotherapy

1 reference

12 December 2020

Molecular mechanisms of expression of Lewis b antigen and other type I Lewis antigens in human colorectal cancer

1 reference

12 December 2020

Structural variations of O-linked oligosaccharides present in leukosialin isolated from erythroid, myeloid, and T-lymphoid cell lines

1 reference

12 December 2020

Colon adenoma and cancer cells aberrantly express the leukocyte-associated sialoglycoprotein CD43

1 reference

12 December 2020

Enhanced sialylation of mucin-associated carbohydrate structures in human colon cancer metastasis

1 reference

12 December 2020

Differential expression of UN1, early thymocyte-associated sialoglycoprotein, in breast normal tissue, benign disease and carcinomas

1 reference

12 December 2020

Fetal ontogeny and tumor expression of the early thymic antigen UN1

1 reference

12 December 2020

Is carcino-embryonic antigen useful in the follow-up management of patients with colorectal liver metastases?

1 reference

12 December 2020

Thomsen-Friedenreich and Tn antigens in nipple fluid: carbohydrate biomarkers for breast cancer detection

1 reference

12 December 2020

M-ficolin and leukosialin (CD43): new partners in neutrophil adhesion

1 reference

12 December 2020

Serum tumor marker CA 15.3 and stage are the two most powerful predictors of survival in primary breast cancer

1 reference

12 December 2020

Benign causes of increased serum CA-125 concentration

1 reference

12 December 2020

Elevated serum CA 125 levels prior to diagnosis of ovarian neoplasia: relevance for early detection of ovarian cancer

1 reference

12 December 2020

Metalloprotease and serine protease are involved in cleavage of CD43, CD44, and CD16 from stimulated human granulocytes. Induction of cleavage of L-selectin via CD16

1 reference

12 December 2020

Clinical evaluation of the simultaneous determination of CA 15-3, CA 125 and sHER2 in breast cancer

1 reference

12 December 2020

Specificity and Affinity of 26 Monoclonal Antibodies against the CA 125 Antigen: First Report from the ISOBM TD-1 Workshop

1 reference

12 December 2020

Induction of CD43 expression during activation and terminal differentiation of human B cells

1 reference

12 December 2020

Glycosylation effects on cancer development

1 reference

12 December 2020

Comparison of CEA, MCA, CA 15-3 and CA 27-29 in follow-up and monitoring therapeutic response in breast cancer patients

1 reference

12 December 2020

Identifiers

DOI

10.1155/2014/742831

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24689054%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24689054%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

24689054

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24689054%20AND%20SRC:MED&resulttype=core&format=json