Transcriptional control of the inflammatory response (Q37622051)

21 August 2017

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title

Transcriptional control of the inflammatory response (English)

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21 August 2017

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Ruslan Medzhitov

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21 August 2017

Tiffany Horng

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21 August 2017

1 October 2009

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Nature Reviews Immunology

21 August 2017

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21 August 2017

9

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21 August 2017

692-703

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21 August 2017

10

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Inflammation and metabolic disorders

21 August 2017

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Origin and physiological roles of inflammation

31 March 2020

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Points of control in inflammation

31 March 2020

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Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics

31 March 2020

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Systems biology of transcription control in macrophages

31 March 2020

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CATERPILLERs, pyrin and hereditary immunological disorders

31 March 2020

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Sterol regulatory element-binding proteins: activators of cholesterol and fatty acid biosynthesis

31 March 2020

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Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

31 March 2020

1 reference

31 March 2020

Biology of HIF-1alpha

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The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response

31 March 2020

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The PAS superfamily: sensors of environmental and developmental signals

31 March 2020

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Shared principles in NF-kappaB signaling

31 March 2020

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Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.

31 March 2020

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Achieving stability of lipopolysaccharide-induced NF-kappaB activation

31 March 2020

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Stimulus specificity of gene expression programs determined by temporal control of IKK activity

31 March 2020

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Function of C/EBPdelta in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals

31 March 2020

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Transcriptional control of granulocyte and monocyte development

31 March 2020

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Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors

31 March 2020

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Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.

31 March 2020

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The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

31 March 2020

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A fourth IkappaB protein within the NF-kappaB signaling module

31 March 2020

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Integrating computational and biochemical studies to explore mechanisms in NF-{kappa}B signaling

31 March 2020

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31 March 2020

The mammalian epigenome

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p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment

31 March 2020

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Dynamic acetylation of all lysine 4-methylated histone H3 in the mouse nucleus: analysis at c-fos and c-jun

31 March 2020

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A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

31 March 2020

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Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

31 March 2020

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Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation

31 March 2020

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The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing

31 March 2020

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

31 March 2020

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Control of inducible gene expression by signal-dependent transcriptional elongation

31 March 2020

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ATP-dependent nucleosome remodeling

31 March 2020

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Induction of TLR4-target genes entails calcium/calmodulin-dependent regulation of chromatin remodeling

31 March 2020

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Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response

31 March 2020

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Class-specific regulation of pro-inflammatory genes by MyD88 pathways and IkappaBzeta

31 March 2020

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A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling

31 March 2020

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Modifying gene expression programs by altering core promoter chromatin architecture.

31 March 2020

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Interactions of NF-kappaB with chromatin: the art of being at the right place at the right time

31 March 2020

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Primary response genes induced by growth factors and tumor promoters

31 March 2020

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A role for cofactor-cofactor and cofactor-histone interactions in targeting p300, SWI/SNF and Mediator for transcription

31 March 2020

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Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta

31 March 2020

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One nucleotide in a kappaB site can determine cofactor specificity for NF-kappaB dimers

31 March 2020

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Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.

31 March 2020

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Interferon regulatory factor-3-mediated activation of the interferon-sensitive response element by Toll-like receptor (TLR) 4 but not TLR3 requires the p65 subunit of NF-kappa.

31 March 2020

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The kappa B DNA sequence from the HIV long terminal repeat functions as an allosteric regulator of HIV transcription

31 March 2020

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Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

31 March 2020

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Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint

31 March 2020

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A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation

31 March 2020

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Negative regulation of toll-like receptor-mediated immune responses

31 March 2020

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Identification of the rel family members required for virus induction of the human beta interferon gene

31 March 2020

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Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

31 March 2020

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IkappaBNS inhibits induction of a subset of Toll-like receptor-dependent genes and limits inflammation.

31 March 2020

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BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophages

31 March 2020

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Negative regulation of toll-like receptor signaling by NF-kappaB p50 ubiquitination blockade

31 March 2020

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The nuclear IkappaB protein IkappaBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria

31 March 2020

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IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-alpha production in macrophages

31 March 2020

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Interleukin-10 and the interleukin-10 receptor

31 March 2020

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The primary mechanism of the IL-10-regulated antiinflammatory response is to selectively inhibit transcription

31 March 2020

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Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105

31 March 2020

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Combinatorial roles of nuclear receptors in inflammation and immunity

31 March 2020

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Glucocorticoid augmentation of macrophage capacity for phagocytosis of apoptotic cells is associated with reduced p130Cas expression, loss of paxillin/pyk2 phosphorylation, and high levels of active Rac.

31 March 2020

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Transcriptional repression of atherogenic inflammation: modulation by PPARdelta

31 March 2020

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

31 March 2020

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SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

31 March 2020

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Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways

31 March 2020

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Mycobacterium tuberculosis exerts gene-selective inhibition of transcriptional responses to IFN-gamma without inhibiting STAT1 function

31 March 2020

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Histone modifications and chromatin remodeling during bacterial infections

31 March 2020

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Toxoplasma gondii prevents chromatin remodeling initiated by TLR-triggered macrophage activation

31 March 2020

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Histone modifications induced by a family of bacterial toxins

31 March 2020

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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

31 March 2020

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The LPS-induced transcriptional upregulation of the chicken lysozyme locus involves CTCF eviction and noncoding RNA transcription.

31 March 2020

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MicroRNAs: new regulators of immune cell development and function

31 March 2020

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Evolution and functions of long noncoding RNAs

31 March 2020

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CTCF: master weaver of the genome

31 March 2020

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Post-transcriptional control of cytokine production

31 March 2020

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The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules

31 March 2020

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Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay

31 March 2020

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Gene-specific control of the TLR-induced inflammatory response

31 March 2020

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Epigenetic silencing of tumor necrosis factor alpha during endotoxin tolerance

31 March 2020

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Gene-specific control of inflammation by TLR-induced chromatin modifications

31 March 2020

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Endotoxin tolerance disrupts chromatin remodeling and NF-kappaB transactivation at the IL-1beta promoter

31 March 2020

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Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

31 March 2020

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Chromatin modifications and their function

31 March 2020

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The language of covalent histone modifications

31 March 2020

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Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4

31 March 2020

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Imaging Drosophila gene activation and polymerase pausing in vivo

31 March 2020

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A chromatin landmark and transcription initiation at most promoters in human cells

31 March 2020

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RNA polymerase is poised for activation across the genome

31 March 2020

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RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo

31 March 2020

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Expanded nuclear roles for IkappaBs

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19859064

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transcription factors that regulate monocyte/macrophage differentiation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19859064

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRI2634

1 reference

21 August 2017

1 reference

PubMed ID

19859064