GLUT1 as a therapeutic target in hepatocellular carcinoma (Q37623840)

21 August 2017

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title

GLUT1 as a therapeutic target in hepatocellular carcinoma (English)

1 reference

21 August 2017

Thomas Amann

1

1 reference

PubMed ID

19874261

21 August 2017

Claus Hellerbrand

series ordinal

2

1 reference

PubMed ID

19874261

21 August 2017

language of work or name

English

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publication date

1 December 2009

1 reference

Expert Opinion on Therapeutic Targets

21 August 2017

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21 August 2017

13

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21 August 2017

12

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21 August 2017

1411-1427

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Hepatocellular carcinoma pathogenesis: from genes to environment

21 August 2017

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21 January 2018

Cancer statistics, 2008

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Hepatocellular carcinoma: recent trends in the United States

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307509

Hepatocellular carcinoma in cirrhosis: incidence and risk factors

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307509

Focus on hepatocellular carcinoma.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307509

Sorafenib in advanced hepatocellular carcinoma

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307509

Molecular targeted therapies in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Commentary: Sorafenib -- the end of a long journey in search of systemic therapy for hepatocellular carcinoma, or the beginning?

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307509

GLUT1 expression is increased in hepatocellular carcinoma and promotes tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review)

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307509

The SLC2 family of facilitated hexose and polyol transporters

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307509

Facilitated hexose transporters: new perspectives on form and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Mouse glucose transporter 9 splice variants are expressed in adult liver and kidney and are up-regulated in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Measurement of GLUT mRNA in liver of fetal and neonatal rats using a novel method of quantitative polymerase chain reaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

GLUT14, a duplicon of GLUT3, is specifically expressed in testis as alternative splice forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Characterization of the human SLC2A11 (GLUT11) gene: alternative promoter usage, function, expression, and subcellular distribution of three isoforms, and lack of mouse orthologue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Cloning and characterization of glucose transporter 11, a novel sugar transporter that is alternatively spliced in various tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Glucose transporter 1, distribution in the brain and in neural disorders: its relationship with transport of neuroactive drugs through the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

GLUT2 is a high affinity glucosamine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Functional expression of rat GLUT 1 glucose transporter in Dictyostelium discoideum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Glucose transporter proteins in brain: delivery of glucose to neurons and glia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Molecular determinants of sugar transport regulation by ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

The predicted ATP-binding domains in the hexose transporter GLUT1 critically affect transporter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Over-expression of facilitative glucose transporter genes in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Glucose uptake inhibitor sensitizes cancer cells to daunorubicin and overcomes drug resistance in hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Glut-1 as a therapeutic target: increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Hypoxia-independent overexpression of hypoxia-inducible factor 1alpha as an early change in mouse hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Cancer's molecular sweet tooth and the Warburg effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Hypoxia signalling controls metabolic demand

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Modification of gap junctional intercellular communication by changes in extracellular pH in Syrian hamster embryo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Microenvironmental and cellular consequences of altered blood flow in tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Positron emission tomography scanning in the evaluation of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

[18F]fluorodeoxyglucose positron emission tomography correlates with Akt pathway activity but is not predictive of clinical outcome during mTOR inhibitor therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

18F-FDG PET scanning correlates with tissue markers of poor prognosis and predicts mortality for patients after liver resection for colorectal metastases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Correlation of GLUT-1 overexpression, tumor size, and depth of invasion with 18F-2-fluoro-2-deoxy-D-glucose uptake by positron emission tomography in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Hepatocellular expression of a dominant-negative mutant TGF-beta type II receptor accelerates chemically induced hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Lactate stimulates fibroblast expression of hyaluronan and CD44: the Warburg effect revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

The inhibitory effects of flavonoids and antiestrogens on the Glut1 glucose transporter in human erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Direct inhibition of the hexose transporter GLUT1 by tyrosine kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Captopril inhibits glucose accumulation in retinal cells in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

GLUT1-deficiency: barbiturates potentiate haploinsufficiency in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Caloric restriction mimetics: metabolic interventions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Glucose catabolism in the rabbit VX2 tumor model for liver cancer: characterization and targeting hexokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Differential expression of Glut 1 mRNA and protein levels correlates with increased sensitivity to the glyco-conjugated nitric oxide donor (2-glu-SNAP) in different tumor cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

RNA interference-mediated reduction in GLUT1 inhibits serum-induced glucose transport in primary human skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Suppression of facilitative glucose transporter 1 mRNA can suppress tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

The promises and pitfalls of RNA-interference-based therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Structural analysis of the GLUT1 facilitative glucose transporter (review).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

A three-dimensional model of the human facilitative glucose transporter Glut1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Effects of a ketogenic diet on tumor metabolism and nutritional status in pediatric oncology patients: two case reports

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

GLUT1 deficiency syndrome--2007 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Seizure control and acceptance of the ketogenic diet in GLUT1 deficiency syndrome: a 2- to 5-year follow-up of 15 children enrolled prospectively

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Optimizing cancer radiotherapy with 2-deoxy-d-glucose dose escalation studies in patients with glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Positron emission tomography agent 2-deoxy-2-[18F]fluoro-D-glucose has a therapeutic potential in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

The human erythrocyte sugar transporter presents two sugar import sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Characterization and partial purification of liver glucose transporter GLUT2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Characterization of D-fructose transport by rat kidney brush-border membrane vesicles: changes in hypertensive rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

GLUT7: a new intestinal facilitated hexose transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

GLUT8, a novel member of the sugar transport facilitator family with glucose transport activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Immunolocalization of GLUTX1 in the testis and to specific brain areas and vasopressin-containing neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Expression and localisation of GLUT1 and GLUT12 glucose transporters in the pregnant and lactating rat mammary gland.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Glucose transporter GLUT12-functional characterization in Xenopus laevis oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Expression of Class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Glucose transporter GLUT1 expression is an stage-independent predictor of clinical outcome in adrenocortical carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Expression of glucose transporters and hexokinase II in cholangiocellular carcinoma compared using [18F]-2-fluro-2-deoxy-D-glucose positron emission tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Nox-generated ROS modulate glucose uptake in a leukaemic cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Gene expression of GLUT3 and GLUT1 glucose transporters in human brain tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Immunohistochemical expression of human erythrocyte glucose transporter and fatty acid synthase in infiltrating breast carcinomas and adjacent typical/atypical hyperplastic or normal breast tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Sodium/iodide symporter expression in primary lung cancer and comparison with glucose transporter 1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Differential expression of facilitative glucose transporter (GLUT) genes in primary lung cancers and their liver metastases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Overexpression of Glut-1 and increased glucose metabolism in tumors are associated with a poor prognosis in patients with oral squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Prognostic value of facilitative glucose transporter Glut-1 in oral squamous cell carcinomas treated by surgical resection; results of EORTC Translational Research Fund studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

GLUT-1 expression in ovarian carcinoma: association with survival and response to chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

GLUT1 mRNA and protein expression in ovarian borderline tumors and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Expression and localization of GLUT1 and GLUT12 in prostate carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Glucose transporter 1 (GLUT1) expression is associated with intestinal type of gastric carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

GLUT1 glucose transporter expression in benign and malignant thyroid nodules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Glucose transporter 1 gene expression is related to thyroid neoplasms with an unfavorable prognosis: an immunohistochemical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Interactions of androgens, green tea catechins and the antiandrogen flutamide with the external glucose-binding site of the human erythrocyte glucose transporter GLUT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Structural basis of GLUT1 inhibition by cytoplasmic ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Dioxin affects glucose transport via the arylhydrocarbon receptor signal cascade in pluripotent embryonic carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

A novel inhibitor of glucose uptake sensitizes cells to FAS-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Expression of the rat GLUT1 glucose transporter in the yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Glucose metabolism as a target of histone deacetylase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Immunogold study of effects of prenatal exposure to lipopolysaccharide and/or valproic acid on the rat blood-brain barrier vessels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Glucose transporter type 1 deficiency syndrome (Glut1DS): methylxanthines potentiate GLUT1 haploinsufficiency in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Interactions of ATP, oestradiol, genistein and the anti-oestrogens, faslodex (ICI 182780) and tamoxifen, with the human erythrocyte glucose transporter, GLUT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

The differential role of Cys-421 and Cys-429 of the Glut1 glucose transporter in transport inhibition by p-chloromercuribenzenesulfonic acid (pCMBS) or cytochalasin B (CB)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Small hepatocellular carcinoma: is radiofrequency ablation combined with transcatheter arterial chemoembolization more effective than radiofrequency ablation alone for treatment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

Relation of a Hypoxia Metagene Derived from Head and Neck Cancer to Prognosis of Multiple Cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307509

10.1517/14728220903307509

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference

PubMed ID

19874261