Secreted Frizzled-related protein 2 as a target in antifibrotic therapeutic intervention (Q37629036)

21 August 2017

Secreted Frizzled-related protein 2 as a target in antifibrotic therapeutic intervention (English)

1 reference

21 August 2017

Michalis Mastri

1

1 reference

21 August 2017

Zaeem Shah

2

1 reference

21 August 2017

Karin Hsieh

3

1 reference

21 August 2017

Xiaowen Wang

4

1 reference

21 August 2017

Bailey Wooldridge

5

1 reference

21 August 2017

Sean Martin

6

1 reference

21 August 2017

Gen Suzuki

7

1 reference

21 August 2017

Techung Lee

8

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21 August 2017

11 December 2013

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American Journal of Physiology - Cell Physiology

21 August 2017

1 reference

21 August 2017

306

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21 August 2017

6

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21 August 2017

C531-9

1 reference

describes a project that uses

21 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3948976/fullTextXML

inferred from PubMed Central ID database lookup

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Cellular mechanisms of tissue fibrosis. 2. Contributory pathways leading to myocardial fibrosis: moving beyond collagen expression

23 August 2017

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Activation of Toll-like receptor 3 amplifies mesenchymal stem cell trophic factors and enhances therapeutic potency

23 August 2017

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Mechanisms of fibrosis: therapeutic translation for fibrotic disease

23 August 2017

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23 August 2017

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Intramuscular VEGF activates an SDF1-dependent progenitor cell cascade and an SDF1-independent muscle paracrine cascade for cardiac repair

23 August 2017

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Aging and Cardiac Fibrosis.

23 August 2017

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23 August 2017

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Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction

23 August 2017

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Activation of host tissue trophic factors through JAK-STAT3 signaling: a mechanism of mesenchymal stem cell-mediated cardiac repair

23 August 2017

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sFRP2 Suppression of Bone Morphogenic Protein (BMP) and Wnt Signaling Mediates Mesenchymal Stem Cell (MSC) Self-renewal Promoting Engraftment and Myocardial Repair

23 August 2017

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Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling

23 August 2017

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Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation

23 August 2017

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The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma

23 August 2017

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Secreted frizzled-related protein 4: an angiogenesis inhibitor.

23 August 2017

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Vascular endothelial growth factor (VEGF) as a key therapeutic trophic factor in bone marrow mesenchymal stem cell-mediated cardiac repair

23 August 2017

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Intramuscular VEGF repairs the failing heart: role of host-derived growth factors and mobilization of progenitor cells

23 August 2017

1 reference

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Osteopontin: role in extracellular matrix deposition and myocardial remodeling post-MI.

23 August 2017

1 reference

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Chemokines and cardiac fibrosis.

23 August 2017

1 reference

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Basement membrane proteoglycans: modulators Par Excellence of cancer growth and angiogenesis.

23 August 2017

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Heart failure therapy mediated by the trophic activities of bone marrow mesenchymal stem cells: a noninvasive therapeutic regimen

23 August 2017

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Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction

23 August 2017

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23 August 2017

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VEGF is critical for stem cell-mediated cardioprotection and a crucial paracrine factor for defining the age threshold in adult and neonatal stem cell function.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease

23 August 2017

1 reference

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Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer

23 August 2017

1 reference

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The bone morphogenetic protein 1/Tolloid-like metalloproteinases

23 August 2017

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Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases.

23 August 2017

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Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair

23 August 2017

1 reference

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Ventricular remodeling after infarction and the extracellular collagen matrix: when is enough enough?

23 August 2017

1 reference

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23 August 2017

Engineered antibodies

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Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

23 August 2017

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Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

23 August 2017

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Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes

23 August 2017

1 reference

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Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle

23 August 2017

1 reference

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Vascular protection: A novel nonangiogenic cardiovascular role for vascular endothelial growth factor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Expression of secreted frizzled related proteins 3 and 4 in human ventricular myocardium correlates with apoptosis related gene expression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Angiogenesis in cancer, vascular, rheumatoid and other disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Myofibroblast-mediated mechanisms of pathological remodelling of the heart

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Assessment of gelatinases (MMP-2 and MMP-9) by gelatin zymography

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

H-Ras-specific upregulation of granulocyte colony-stimulating factor promotes human breast cell invasion via matrix metalloproteinase-2.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Substrate-specific modulation of a multisubstrate proteinase. C-terminal processing of fibrillar procollagens is the only BMP-1-dependent activity to be enhanced by PCPE-1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Myocardial oxidative stress, osteogenic phenotype, and energy metabolism are differentially involved in the initiation and early progression of delta-sarcoglycan-null cardiomyopathy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Transforming growth factor beta inhibitory element in the rabbit matrix metalloproteinase-1 (collagenase-1) gene functions as a repressor of constitutive transcription

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Progressive cardiac dysfunction and fibrosis in the cardiomyopathic hamster and effects of growth hormone and angiotensin-converting enzyme inhibition

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Stem cell therapy independent of stemness

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Limiting fibrosis after myocardial infarction

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Adenoviral expression of vascular endothelial growth factor splice variants differentially regulate bone marrow-derived mesenchymal stem cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Comparative genomics on SFRP2 orthologs.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Inhibition of matrix metalloproteinases prevents cardiac hypertrophy induced by beta-adrenergic stimulation in rats

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Unbalanced collagenases/TIMP-1 expression and epithelial apoptosis in experimental lung fibrosis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Functional characterization of adherent synovial fluid cells in rheumatoid arthritis: destructive potential in vitro and in vivo

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Hemodynamic and histomorphometric characteristics of dilated cardiomyopathy of Syrian hamsters (Bio TO-2 strain).

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3948976

Vitronectin: Growth Factor Complexes Hold Potential as a Wound Therapy Approach

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1152%2FAJPCELL.00238.2013

Mesenchymal stem cells and cardiac regeneration: a sophisticated approach depends on trophic effects--what's left over? Focus on "Activation of Toll-like receptor 3 amplifies mesenchymal stem cell trophic factors and enhances therapeutic potency"

21 January 2018

1 reference

12 December 2020

Calpain-mediated proteolytic cleavage of troponin I induced by hypoxia or metabolic inhibition in cultured neonatal cardiomyocytes

1 reference

12 December 2020

The cardiomyopathic hamster as model of early myocardial aging

1 reference

12 December 2020

sFRPs: a declaration of (Wnt) independence

1 reference

12 December 2020

A new molecular target for blunting organ fibrosis. Focus on "Secreted Frizzled-related protein 2 as a target in antifibrotic therapeutic intervention"

1 reference

12 December 2020

HGF and VEGF: a dynamic duo

1 reference

12 December 2020

Type I collagen can function as a reservoir of basic fibroblast growth factor

1 reference

12 December 2020

10.1152/AJPCELL.00238.2013

Identifiers

DOI

1 reference

21 August 2017

1 reference

21 August 2017

PubMed publication ID

24336656

1 reference