S100A8/A9: a mediator of severe asthma pathogenesis and morbidity? (Q37629632)

21 August 2017

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title

S100A8/A9: a mediator of severe asthma pathogenesis and morbidity? (English)

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21 August 2017

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1

Andrew J Halayko

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21 August 2017

Saeid Ghavami

2

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21 August 2017

publication date

1 October 2009

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Canadian Journal of Physiology and Pharmacology

21 August 2017

published in

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21 August 2017

volume

87

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21 August 2017

issue

10

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21 August 2017

page(s)

743-755

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Poor control increases the economic cost of asthma. A multicentre population-based study.

21 August 2017

cites work

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Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma

21 January 2018

1 reference

Disulfide-linked S100 beta dimers and signal transduction

21 January 2018

1 reference

Airway smooth muscle as a model for new investigative drugs in asthma

21 January 2018

1 reference

Regulation of procollagen I (α1) by interleukin‐4 in human bronchial fibroblasts: a possible role in airway remodelling in asthma

21 January 2018

1 reference

The calcium-binding proteins MRP8 and MRP14 form a membrane-associated heterodimer in a subset of monocytes/macrophages present in acute but absent in chronic inflammatory lesions

21 January 2018

1 reference

DAMPs, PAMPs and alarmins: all we need to know about danger

21 January 2018

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Understanding RAGE, the receptor for advanced glycation end products

21 January 2018

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Interaction between S100A8/A9 and annexin A6 is involved in the calcium-induced cell surface exposition of S100A8/A9.

21 January 2018

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Asthma. From bronchoconstriction to airways inflammation and remodeling

21 January 2018

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S100A8 chemotactic protein is abundantly increased, but only a minor contributor to LPS-induced, steroid resistant neutrophilic lung inflammation in vivo

21 January 2018

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Increased sensitivity of asthmatic airway smooth muscle cells to prostaglandin E2 might be mediated by increased numbers of E-prostanoid receptors

21 January 2018

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Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-beta, IL-11, IL-17, and type I and type III collagen expression

21 January 2018

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PAR-2 activation, PGE2, and COX-2 in human asthmatic and nonasthmatic airway smooth muscle cells

21 January 2018

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Severe asthma in adults: what are the important questions?

21 January 2018

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The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment

21 January 2018

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Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

21 January 2018

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Advances in neutrophil biology: clinical implications

21 January 2018

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Identification of genes differentially expressed in rat alveolar type I cells

21 January 2018

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Intracellular Ca2+ and Zn2+ levels regulate the alternative cell density-dependent secretion of S100B in human glioblastoma cells

21 January 2018

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Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells.

21 January 2018

1 reference

S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles

21 January 2018

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Intracellular and extracellular roles of S100 proteins

21 January 2018

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The S100A8/A9 protein as a partner for the cytosolic factors of NADPH oxidase activation in neutrophils

21 January 2018

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Masquerader: high mobility group box-1 and cancer

21 January 2018

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Anti-TNF therapy: where have we got to in 2005?

21 January 2018

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Proinflammatory S100 proteins in arthritis and autoimmune disease

21 January 2018

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Mechanisms of disease: a 'DAMP' view of inflammatory arthritis

21 January 2018

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S100A8 and S100A9 in inflammation and cancer

21 January 2018

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Mechanism of apoptosis induced by S100A8/A9 in colon cancer cell lines: the role of ROS and the effect of metal ions.

21 January 2018

1 reference

S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2.

21 January 2018

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S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway

21 January 2018

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Rho-kinase as a drug target for the treatment of airway hyperrespon-siveness in asthma

21 January 2018

1 reference

Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids

21 January 2018

1 reference

Proteomic identification of in vivo substrates for matrix metalloproteinases 2 and 9 reveals a mechanism for resolution of inflammation

21 January 2018

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Mechanisms of inflammation-mediated airway smooth muscle plasticity and airways remodeling in asthma

21 January 2018

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Airway smooth muscle phenotype and function: interactions with current asthma therapies

21 January 2018

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The role of high mobility group box1 in pulmonary fibrosis

21 January 2018

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New perspectives on S100 proteins: a multi-functional Ca(2+)-, Zn(2+)- and Cu(2+)-binding protein family

21 January 2018

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S100A8 and S100A9 activate MAP kinase and NF-kappaB signaling pathways and trigger translocation of RAGE in human prostate cancer cells

21 January 2018

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RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides

21 January 2018

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The mechanisms, diagnosis, and management of severe asthma in adults

21 January 2018

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Epithelial-mesenchymal interactions in the pathogenesis of asthma

21 January 2018

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Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities

21 January 2018

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Tumour necrosis factor (TNFalpha) as a novel therapeutic target in symptomatic corticosteroid dependent asthma

21 January 2018

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Asthma control or severity: that is the question

21 January 2018

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High level expression and dimer characterization of the S100 EF-hand proteins, migration inhibitory factor-related proteins 8 and 14.

21 January 2018

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Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways

21 January 2018

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Clinical relevance of airway remodelling in airway diseases

21 January 2018

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Airway smooth muscle as a target of asthma therapy: history and new directions

21 January 2018

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Functional and clinical aspects of the myelomonocyte protein calprotectin

21 January 2018

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Airway smooth muscle cell proliferation is increased in asthma

21 January 2018

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Extracellular matrix proteins modulate asthmatic airway smooth muscle cell proliferation via an autocrine mechanism

21 January 2018

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A partial catalog of proteins secreted by epidermal keratinocytes in culture

21 January 2018

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The regulatory role of MRP8 (S100A8) and MRP14 (S100A9) in the transendothelial migration of human leukocytes

21 January 2018

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Interaction of S100A8/S100A9-arachidonic acid complexes with the scavenger receptor CD36 may facilitate fatty acid uptake by endothelial cells

21 January 2018

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HMGB1: endogenous danger signaling

21 January 2018

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High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

21 January 2018

1 reference

21 January 2018

Neutrophils in asthma

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Formoterol attenuates neutrophilic airway inflammation in asthma

21 January 2018

1 reference

S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature)

21 January 2018

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An update of the S100 nomenclature.

21 January 2018

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Corticosteroids prevent myofibroblast accumulation and airway remodeling in mice

21 January 2018

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Corticosteroid therapy in asthma: predictors of responsiveness

21 January 2018

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A soluble protein characteristic of the nervous system

21 January 2018

1 reference

S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity

21 January 2018

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Regulation of S100A8/A9 (calprotectin) binding to tumor cells by zinc ion and its implication for apoptosis-inducing activity

21 January 2018

1 reference

Tissue fibrocytes in patients with mild asthma: a possible link to thickness of reticular basement membrane?

21 January 2018

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Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis

21 January 2018

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Increased neutrophil numbers and IL-8 levels in airway secretions in acute severe asthma: Clinical and biologic significance

21 January 2018

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Structural and functional insights into RAGE activation by multimeric S100B

21 January 2018

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Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

21 January 2018

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High mobility group box 1 protein interacts with multiple Toll-like receptors

21 January 2018

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The structure of calcyclin reveals a novel homodimeric fold for S100 Ca(2+)-binding proteins

21 January 2018

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Airway mucus hypersecretion in asthma: an undervalued pathology?

21 January 2018

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Phagocyte-specific S100 proteins: a novel group of proinflammatory molecules

21 January 2018

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Plasma levels of the leucocyte L1 protein in febrile conditions: relation to aetiology, number of leucocytes in blood, blood sedimentation reaction and C-reactive protein

21 January 2018

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Calcium-dependent and -independent interactions of the S100 protein family.

21 January 2018

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The three-dimensional structure of Ca(2+)-bound calcyclin: implications for Ca(2+)-signal transduction by S100 proteins

21 January 2018

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The S100 family of EF-hand calcium-binding proteins: functions and pathology

21 January 2018

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Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family

21 January 2018

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Association between neutrophilic airway inflammation and airflow limitation in adults with asthma.

21 January 2018

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Receptor for advanced glycation end-products is a marker of type I lung alveolar cells

21 January 2018

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Elevated serum macrophage inhibitory factor-related protein (MRP) 8/14 levels in advanced HIV infection and during disease exacerbation.

21 January 2018

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The S100A8/A9 heterodimer amplifies proinflammatory cytokine production by macrophages via activation of nuclear factor kappa B and p38 mitogen-activated protein kinase in rheumatoid arthritis

21 January 2018

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21 January 2018

TLR signaling pathways

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Inhibition of human papillomavirus type 16 E7 phosphorylation by the S100 MRP-8/14 protein complex

21 January 2018

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RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis

21 January 2018

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MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes

21 January 2018

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Biophysical characterization of S100A8 and S100A9 in the absence and presence of bivalent cations

21 January 2018

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Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

21 January 2018

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Correlation between airway responsiveness and proteoglycan production by bronchial fibroblasts from normal and asthmatic subjects

21 January 2018

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21 January 2018

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The role of the receptor for advanced glycation end-products in lung fibrosis

21 January 2018

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Phagocyte-specific S100 proteins are released from affected mucosa and promote immune responses during inflammatory bowel disease

21 January 2018

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Epithelial Damage and Angiogenesis in the Airways of Children with Asthma

21 January 2018

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Metal Chelation and Inhibition of Bacterial Growth in Tissue Abscesses

21 January 2018

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Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1139/Y09-054

1 reference

release_quisg6cxbjbwvg2eaepthwewwy

21 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/quisg6cxbjbwvg2eaepthwewwy

mapped directly with Wikidata item

24 November 2022

based on heuristic

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