Cellular cholesterol regulates ubiquitination and degradation of the cholesterol export proteins ABCA1 and ABCG1 (Q37635789)

21 August 2017

Cellular cholesterol regulates ubiquitination and degradation of the cholesterol export proteins ABCA1 and ABCG1 (English)

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21 August 2017

protein ubiquitination

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9

Wendy Jessup

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21 August 2017

Victar Hsieh

1

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21 August 2017

Mi-Jurng Kim

2

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21 August 2017

Ingrid C Gelissen

3

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21 August 2017

Andrew J Brown

4

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21 August 2017

Cecilia Sandoval

5

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21 August 2017

Jeannette C Hallab

6

1 reference

21 August 2017

Maaike Kockx

7

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21 August 2017

Mathew Traini

8

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21 August 2017

Leonard Kritharides

10

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21 August 2017

language of work or name

English

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publication date

5 February 2014

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Journal of Biological Chemistry

21 August 2017

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21 August 2017

289

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21 August 2017

11

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21 August 2017

7524-7536

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describes a project that uses

21 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3953266/fullTextXML

inferred from PubMed Central ID database lookup

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A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.

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The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus

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Ubiquitination is associated with lysosomal degradation of cell surface-resident ATP-binding cassette transporter A1 (ABCA1) through the endosomal sorting complex required for transport (ESCRT) pathway.

6 September 2017

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Cholesterol-dependent degradation of squalene monooxygenase, a control point in cholesterol synthesis beyond HMG-CoA reductase

14 September 2017

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The COP9 signalosome controls ubiquitinylation of ABCA1.

14 September 2017

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Direct interaction of nuclear liver X receptor-beta with ABCA1 modulates cholesterol efflux

14 September 2017

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Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice

14 September 2017

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SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR.

14 September 2017

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ABCA1 and ABCG1 synergize to mediate cholesterol export to apoA-I.

14 September 2017

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Phosphorylation and stabilization of ATP binding cassette transporter A1 by synthetic amphiphilic helical peptides

14 September 2017

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Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism

14 September 2017

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Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation

28 September 2017

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Unsaturated fatty acids inhibit cholesterol efflux from macrophages by increasing degradation of ATP-binding cassette transporter A1.

28 September 2017

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The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase

28 September 2017

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Lactacystin, proteasome function, and cell fate

28 September 2017

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Calpain-mediated ABCA1 degradation: post-translational regulation of ABCA1 for HDL biogenesis

28 September 2017

1 reference

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Expression and stability of two isoforms of ABCG1 in human vascular cells

25 June 2018

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Species variation in ABCG1 isoform expression: implications for the use of animal models in elucidating ABCG1 function

25 June 2018

1 reference

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Cholesterol accumulation inhibits ER to Golgi transport and protein secretion: studies of apolipoprotein E and VSVGt.

1 September 2018

1 reference

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Calpain-mediated cleavage negatively regulates the expression level of ABCG1.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953266

Stimulation of cholesterol efflux by LXR agonists in cholesterol-loaded human macrophages is ABCA1-dependent but ABCG1-independent

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953266

OSBP negatively regulates ABCA1 protein stability

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953266

Coexistence of foam cells and hypocholesterolemia in mice lacking the ABC transporters A1 and G1.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953266

Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953266

The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953266

Regulation and Mechanisms of ATP-Binding Cassette Transporter A1-Mediated Cellular Cholesterol Efflux

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953266

ABCA1 mRNA and protein distribution patterns predict multiple different roles and levels of regulation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953266

ATP-binding cassette transporter A1 contains an NH2-terminal signal anchor sequence that translocates the protein's first hydrophilic domain to the exoplasmic space.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953266

Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953266

Apolipoprotein A-I-mediated efflux of sterols from oxidized LDL-loaded macrophages

1 September 2018

1 reference

12 December 2020

Regulation of serum-induced lipid accumulation in human monocyte-derived macrophages by interferon-gamma. Correlations with apolipoprotein E production, lipoprotein lipase activity and LDL receptor-related protein expression

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12 December 2020

Total body ABCG1 expression protects against early atherosclerotic lesion development in mice

1 reference

12 December 2020

Proteasomal inhibition promotes ATP-binding cassette transporter A1 (ABCA1) and ABCG1 expression and cholesterol efflux from macrophages in vitro and in vivo

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12 December 2020

Identifiers

DOI

10.1074/JBC.M113.515890

1 reference

21 August 2017

1 reference

21 August 2017

PubMed publication ID

24500716

1 reference