Regulation and Mechanisms of ATP-Binding Cassette Transporter A1-Mediated Cellular Cholesterol Efflux (Q44435127)

2 December 2017

Regulation and mechanisms of ATP-binding cassette transporter A1-mediated cellular cholesterol efflux (English)

1 reference

2 December 2017

Regulation and Mechanisms of ATP-Binding Cassette Transporter A1-Mediated Cellular Cholesterol Efflux (English)

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Cardiology and cardiovascular medicine

31 December 2023

main subject

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

31 December 2023

author name string

Nan Wang

1

1 reference

2 December 2017

Alan R. Tall

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12738681

31 December 2023

language of work or name

English

0 references

publication date

8 May 2003

1 reference

Arteriosclerosis, Thrombosis, and Vascular Biology

2 December 2017

1 reference

2 December 2017

23

1 reference

2 December 2017

7

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2 December 2017

1178-1184

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The response-to-retention hypothesis of atherogenesis reinforced

2 December 2017

1

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

31 December 2023

Atherosclerosis

2

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Tangier disease as a test of the reverse cholesterol transport hypothesis

31 December 2023

3

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

31 December 2023

4

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

31 December 2023

5

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

31 December 2023

6

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1.

31 December 2023

7

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages

31 December 2023

8

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Increased atherosclerosis in hyperlipidemic mice with inactivation of ABCA1 in macrophages

31 December 2023

9

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice

31 December 2023

10

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Increased ABCA1 activity protects against atherosclerosis.

31 December 2023

11

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

31 December 2023

12

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

31 December 2023

13

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Proceedings of the National Academy of Sciences of the United States of America

31 December 2023

14

14

14.

2002

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjögren's Syndrome

31 December 2023

15

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

31 December 2023

16

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1.

31 December 2023

17

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Alpha-helical requirements for free apolipoproteins to generate HDL and to induce cellular lipid efflux

31 December 2023

18

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterol

31 December 2023

20

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier Disease

31 December 2023

21

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages

31 December 2023

22

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Specific docking of apolipoprotein A-I at the cell surface requires a functional ABCA1 transporter

31 December 2023

23

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Evaluation of the role of phosphatidylserine translocase activity in ABCA1-mediated lipid efflux

31 December 2023

24

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein

31 December 2023

25

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

The role of apolipoprotein A-I helix 10 in apolipoprotein-mediated cholesterol efflux via the ATP-binding cassette transporter ABCA1.

31 December 2023

26

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I

31 December 2023

27

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes.

31 December 2023

29

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Distinct sites on ABCA1 control distinct steps required for cellular release of phospholipids.

31 December 2023

30

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.

31 December 2023

31

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein

31 December 2023

32

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Binding of high density lipoprotein (HDL) and discoidal reconstituted HDL to the HDL receptor scavenger receptor class B type I. Effect of lipid association and APOA-I mutations on receptor binding

31 December 2023

33

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations

31 December 2023

34

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Apolipoprotein specificity for lipid efflux by the human ABCAI transporter

31 December 2023

35

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Evidence that the initial up-regulation of phosphatidylcholine biosynthesis in free cholesterol-loaded macrophages is an adaptive response that prevents cholesterol-induced cellular necrosis. Proposed role of an eventual failure of this response in

31 December 2023

37

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice.

31 December 2023

38

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Cellular localization and trafficking of the human ABCA1 transporter

31 December 2023

39

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Cholesterol efflux to apolipoprotein AI involves endocytosis and resecretion in a calcium-dependent pathway

31 December 2023

40

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes

31 December 2023

41

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

31 December 2023

42

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation

31 December 2023

43

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

PEST sequences and regulation by proteolysis

31 December 2023

44

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity

31 December 2023

45

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain

31 December 2023

46

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism

31 December 2023

48

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

The amino-terminal hydrophobic region of the small subunit of calcium-activated neutral protease (CANP) is essential for its activation by phosphatidylinositol

31 December 2023

49

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Phosphorylation by the protein kinase CK2 promotes calpain-mediated degradation of IkappaBalpha

31 December 2023

50

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Degradation of CFTR by the ubiquitin-proteasome pathway

31 December 2023

51

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Rescuing protein conformation: prospects for pharmacological therapy in cystic fibrosis

31 December 2023

52

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Unsaturated fatty acids inhibit cholesterol efflux from macrophages by increasing degradation of ATP-binding cassette transporter A1.

31 December 2023

53

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Polyunsaturated fatty acids and acetoacetate downregulate the expression of the ATP-binding cassette transporter A1.

31 December 2023

54

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Membrane lipid domains distinct from cholesterol/sphingomyelin-rich rafts are involved in the ABCA1-mediated lipid secretory pathway

31 December 2023

55

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Sterol efflux to apolipoprotein A-I originates from caveolin-rich microdomains and potentiates PDGF-dependent protein kinase activity

31 December 2023

56

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Apo AI/ABCA1-dependent and HDL3-mediated lipid efflux from compositionally distinct cholesterol-based microdomains

31 December 2023

57

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure

31 December 2023

58

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Differential regulation of apolipoprotein A-I/ATP binding cassette transporter A1-mediated cholesterol and phospholipid release

31 December 2023

59

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Efflux of cellular cholesterol and phospholipid to lipid-free apolipoproteins and class A amphipathic peptides

31 December 2023

60

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Scavenger receptor-BI inhibits ATP-binding cassette transporter 1- mediated cholesterol efflux in macrophages

31 December 2023

61

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

A two-step mechanism for free cholesterol and phospholipid efflux from human vascular cells to apolipoprotein A-1.

31 December 2023

62

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

31 December 2023

63

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

31 December 2023

64

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol

31 December 2023

65

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface

31 December 2023

66

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy

31 December 2023

67

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice

31 December 2023

68

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

31 December 2023

69

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Role of LXRs in control of lipogenesis

31 December 2023

70

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

Calpain inhibitors as therapeutic agents in nerve and muscle degeneration

31 December 2023

71

1 reference

https://api.crossref.org/works/10.1161/01.ATV.0000075912.83860.26

31 December 2023

Identifiers

1 reference

2 December 2017

1 reference