Latest advances in cannabinoid receptor agonists (Q37638736)

21 August 2017

1 reference

title

Latest advances in cannabinoid receptor agonists (English)

1 reference

21 August 2017

0 references

0 references

0 references

0 references

0 references

Alexandros Makriyannis

series ordinal

4

object named as

Alexandros Makriyannis

1 reference

21 August 2017

Ganesh A Thakur

1

1 reference

21 August 2017

Ritesh Tichkule

series ordinal

2

1 reference

21 August 2017

Shama Bajaj

series ordinal

3

1 reference

21 August 2017

language of work or name

English

0 references

publication date

1 December 2009

1 reference

Expert Opinion on Therapeutic Patents

21 August 2017

1 reference

21 August 2017

19

1 reference

21 August 2017

12

1 reference

21 August 2017

1647-1673

1 reference

Molecular characterization of a peripheral receptor for cannabinoids

21 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Molecular cloning, expression and function of the murine CB2 peripheral cannabinoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Molecular cloning of a human cannabinoid receptor which is also expressed in testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Cannabinoid receptor localization in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

International Union of Pharmacology. XXVII. Classification of cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

The endocannabinoid system as an emerging target of pharmacotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Cannabinoid receptors: where they are and what they do.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Should peripheral CB(1) cannabinoid receptors be selectively targeted for therapeutic gain?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

The effects of cannabinoids on the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Emerging role of the cannabinoid receptor CB2 in immune regulation: therapeutic prospects for neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Identification and functional characterization of brainstem cannabinoid CB2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

21 January 2018

Cannabinoid signalling

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Allosteric modulation of the cannabinoid CB1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Positive allosteric modulation of the human cannabinoid (CB) receptor by RTI-371, a selective inhibitor of the dopamine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

The orphan receptor GPR55 is a novel cannabinoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Novel cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

In silico patent searching reveals a new cannabinoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Evidence for novel cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Endocannabinoid signaling in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Regulation of anandamide tissue levels by N-arachidonylglycine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Endogenous cannabinoids in the brain and peripheral tissues: regulation of their levels and control of food intake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Functional role of high-affinity anandamide transport, as revealed by selective inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Structural determinants for recognition and translocation by the anandamide transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Identification of intracellular carriers for the endocannabinoid anandamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Therapeutic potential of endocannabinoid-hydrolysing enzyme inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Overview of the chemical families of fatty acid amide hydrolase and monoacylglycerol lipase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Oxidative metabolism of endocannabinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Non-redundant functions of cyclooxygenases: oxygenation of endocannabinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Crystal structure of rhodopsin: A G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Crystal structure of the ligand-free G-protein-coupled receptor opsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Ligand-binding architecture of human CB2 cannabinoid receptor: evidence for receptor subtype-specific binding motif and modeling GPCR activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Emerging strategies for exploiting cannabinoid receptor agonists as medicines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

The cannabinergic system as a target for anti-inflammatory therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

A review of nabilone in the treatment of chemotherapy-induced nausea and vomiting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Nabilone for the treatment of pain in fibromyalgia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

The use of a synthetic cannabinoid in the management of treatment-resistant nightmares in posttraumatic stress disorder (PTSD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Cannabidiol--recent advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Agonistic properties of cannabidiol at 5-HT1a receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Ajulemic acid (IP-751): synthesis, proof of principle, toxicity studies, and clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Ajulemic acid: A novel cannabinoid produces analgesia without a "high"

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Cannabinoids, endocannabinoids, and related analogs in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Cannabinol derivatives: binding to cannabinoid receptors and inhibition of adenylylcyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Ajulemic acid, a synthetic nonpsychoactive cannabinoid acid, bound to the ligand binding domain of the human peroxisome proliferator-activated receptor gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Dimethylheptyl-THC-11 oic acid: a nonpsychoactive antiinflammatory agent with a cannabinoid template structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Cannabimimetic properties of ajulemic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Adamantyl cannabinoids: a novel class of cannabinergic ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Identification of a potent and highly efficacious, yet slowly desensitizing CB1 cannabinoid receptor agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Novel 1',1'-chain substituted Delta(8)-tetrahydrocannabinols

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Pharmacophoric requirements for the cannabinoid side chain. Probing the cannabinoid receptor subsite at C1'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

C1'-cycloalkyl side chain pharmacophore in tetrahydrocannabinols

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Synthesis and testing of novel phenyl substituted side-Chain analogues of classical cannabinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Synthesis and testing of novel classical cannabinoids: exploring the side chain ligand binding pocket of the CB1 and CB2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Classical/nonclassical hybrid cannabinoids: southern aliphatic chain-functionalized C-6beta methyl, ethyl, and propyl analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Enantiomeric resolution of a novel chiral cannabinoid receptor ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Behavioral comparisons of the stereoisomers of tetrahydrocannabinols.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Enantiomeric cannabidiol derivatives: synthesis and binding to cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

New cannabidiol derivatives: synthesis, binding to cannabinoid receptor, and evaluation of their antiinflammatory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Characterization of the diarylether sulfonylester (-)-(R)-3-(2-hydroxymethylindanyl-4-oxy)phenyl-4,4,4-trifluoro-1-sulfonate (BAY 38-7271) as a potent cannabinoid receptor agonist with neuroprotective properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Neuroprotective and brain edema-reducing efficacy of the novel cannabinoid receptor agonist BAY 38-7271

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

(R)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Highly selective CB(1) cannabinoid receptor ligands and novel CB(1)/VR(1) vanilloid receptor "hybrid" ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of selective ligands for the CB2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Pharmacological characterization of novel water-soluble cannabinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Selective activation of cannabinoid CB2 receptors suppresses neuropathic nociception induced by treatment with the chemotherapeutic agent paclitaxel in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Antinociceptive (aminoalkyl)indoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Conformationally restrained analogues of pravadoline: nanomolar potent, enantioselective, (aminoalkyl)indole agonists of the cannabinoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Aminoalkylindoles: structure-activity relationships of novel cannabinoid mimetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Recent advances in the development of selective ligands for the cannabinoid CB(2) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Indol-3-yl-tetramethylcyclopropyl ketones: effects of indole ring substitution on CB2 cannabinoid receptor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Characterization of a cannabinoid CB2 receptor-selective agonist, A-836339 [2,2,3,3-tetramethyl-cyclopropanecarboxylic acid [3-(2-methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], using in vitro pharmacological assays, in vivo pain models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

In vitro and in vivo characterization of A-796260: a selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Discovery of 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a selective CB2 receptor agonist for the treatment of inflammatory pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Design, synthesis, and biological evaluation of new 1,8-naphthyridin-4(1H)-on-3-carboxamide and quinolin-4(1H)-on-3-carboxamide derivatives as CB2 selective agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Synthesis and biological evaluation of 1,8-naphthyridin-4(1H)-on-3-carboxamide derivatives as new ligands of cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Pharmacomodulations around the 4-oxo-1,4-dihydroquinoline-3-carboxamides, a class of potent CB2-selective cannabinoid receptor ligands: consequences in receptor affinity and functionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Novel 4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives as new CB2 cannabinoid receptors agonists: synthesis, pharmacological properties and molecular modeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Design and synthesis of a novel series of N-alkyl isatin acylhydrazone derivatives that act as selective cannabinoid receptor 2 agonists for the treatment of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

6-Methoxy-N-alkyl isatin acylhydrazone derivatives as a novel series of potent selective cannabinoid receptor 2 inverse agonists: design, synthesis, and binding mode prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Cannabinoid receptor agonist 13, a novel cannabinoid agonist: first in human pharmacokinetics and safety

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Intestinal lymphatic transport enhances the post-prandial oral bioavailability of a novel cannabinoid receptor agonist via avoidance of first-pass metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Imine derivatives as new potent and selective CB2 cannabinoid receptor agonists with an analgesic action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

The SAR studies of novel CB2 selective agonists, benzimidazolone derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Morpholine containing CB2 selective agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Design and synthesis of novel tri-aryl CB2 selective cannabinoid ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

CB2 selective sulfamoyl benzamides: optimization of the amide functionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Resorcinol derivatives: a novel template for the development of cannabinoid CB(1)/CB(2) and CB(2)-selective agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

MBC94, a conjugable ligand for cannabinoid CB 2 receptor imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

Isolation and structure of .DELTA.+- tetrahydrocannabinol and other neutral cannabinoids from hashish

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903436505

10.1517/13543770903436505

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference