Platelet thrombin receptor antagonism and atherothrombosis (Q37641556)

21 August 2017

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Platelet thrombin receptor antagonism and atherothrombosis (English)

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21 August 2017

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13 March 2019

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17 June 2019

31 July 2019

2 October 2019

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18 July 2020

cell surface receptor

1 reference

31 July 2019

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2 October 2019

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15 December 2019

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18 July 2020

Davide Capodanno

2

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Dominick Angiolillo

series ordinal

1

object named as

Dominick J Angiolillo

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21 August 2017

Shinya Goto

3

1 reference

PMCID

2800923

21 August 2017

language of work or name

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30 November 2009

1 reference

PMCID

2800923

21 August 2017

1 January 2010

7 references

13 March 2019

19 March 2019

17 June 2019

31 July 2019

2 October 2019

15 December 2019

18 July 2020

European Heart Journal

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21 August 2017

13 March 2019

19 March 2019

17 June 2019

31 July 2019

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15 December 2019

18 July 2020

31

1 reference

21 August 2017

17-28

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21 August 2017

1

1 reference

Creative Commons Attribution-NonCommercial

21 August 2017

7 references

13 March 2019

19 March 2019

17 June 2019

31 July 2019

2 October 2019

15 December 2019

18 July 2020

on focus list of Wikimedia project

ScienceSource

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23 August 2017

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23 August 2017

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23 August 2017

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Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity

23 August 2017

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Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin

23 August 2017

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23 August 2017

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23 August 2017

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Cloning and characterization of human protease-activated receptor 4

23 August 2017

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23 August 2017

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23 August 2017

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Molecular cloning of a potential proteinase activated receptor

23 August 2017

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23 August 2017

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23 August 2017

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Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

23 August 2017

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23 August 2017

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Binding of thrombin to glycoprotein Ib accelerates the hydrolysis of Par-1 on intact platelets

23 August 2017

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Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin

6 September 2017

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Synergistic action between inhibition of P2Y12/P2Y1 and P2Y12/thrombin in ADP- and thrombin-induced human platelet activation

28 September 2017

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Structure-function analysis of protease-activated receptor 4 tethered ligand peptides. Determinants of specificity and utility in assays of receptor function

25 June 2018

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Integrin signaling: the platelet paradigm

25 June 2018

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Vascular actions of thrombin receptor peptide

25 June 2018

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Identification of a new congenital defect of platelet function characterized by severe impairment of platelet responses to adenosine diphosphate

25 June 2018

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Safety and exploratory efficacy of the novel thrombin receptor (PAR-1) antagonist SCH530348 for non-ST-segment elevation acute coronary syndrome

25 June 2018

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The in-vitro effects of E5555, a protease-activated receptor (PAR)-1 antagonist, on platelet biomarkers in healthy volunteers and patients with coronary artery disease.

1 September 2018

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Safety and tolerability of SCH 530348 in patients undergoing non-urgent percutaneous coronary intervention: a randomised, double-blind, placebo-controlled phase II study

1 September 2018

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Impact of P2Y(12) inhibitory effects induced by clopidogrel on platelet procoagulant activity in type 2 diabetes mellitus patients.

1 September 2018

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1 September 2018

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The active metabolite of prasugrel inhibits adenosine diphosphate- and collagen-stimulated platelet procoagulant activities

1 September 2018

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Prasugrel versus clopidogrel in patients with acute coronary syndromes

1 September 2018

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Platelet adhesion and signaling induced by the octapeptide primary binding sequence (KOGEOGPK) from type III collagen

1 September 2018

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Impaired hemostasis and protection against thrombosis in protease-activated receptor 4-deficient mice is due to lack of thrombin signaling in platelets

1 September 2018

1 reference

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Platelets, after exposure to a high shear stress, induce IL-10-producing, mature dendritic cells in vitro.

1 September 2018

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The relative importance of the ADP receptors, P2Y12 and P2Y1, in thrombin-induced platelet activation.

1 September 2018

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Reduced thrombus cohesion in an ex vivo human model of arterial thrombosis induced by clopidogrel treatment: kinetics of the effect and influence of single and double loading-dose regimens

1 September 2018

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Platelet ADP receptors contribute to the initiation of intravascular coagulation

1 September 2018

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Inhibition of arterial thrombosis by a protease-activated receptor 1 antagonist, FR171113, in the guinea pig.

1 September 2018

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Evidence for a role for Galphai1 in mediating weak agonist-induced platelet aggregation in human platelets: reduced Galphai1 expression and defective Gi signaling in the platelets of a patient with a chronic bleeding disorder

1 September 2018

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Blockade of the thrombin receptor protease-activated receptor-1 with a small-molecule antagonist prevents thrombus formation and vascular occlusion in nonhuman primates.

1 September 2018

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Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling

1 September 2018

1 reference

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Defective platelet activation in G alpha(q)-deficient mice.

1 September 2018

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1 September 2018

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12 December 2020

Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors

1 reference

12 December 2020

Platelet P2Y12 receptors enhance signalling towards procoagulant activity and thrombin generation. A study with healthy subjects and patients at thrombotic risk

1 reference

12 December 2020

A key role of adenosine diphosphate in the irreversible platelet aggregation induced by the PAR1-activating peptide through the late activation of phosphoinositide 3-kinase

1 reference

12 December 2020

In vitro antiplatelet profile of FR171113, a novel non-peptide thrombin receptor antagonist

1 reference

12 December 2020

ADP induces partial platelet aggregation without shape change and potentiates collagen-induced aggregation in the absence of Galphaq

1 reference

12 December 2020

Prevention of the hypercontractile response to thrombin by proteinase-activated receptor-1 antagonist in subarachnoid hemorrhage

1 reference

12 December 2020

Cardiovascular biology. Platelets and proteases

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12 December 2020

CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism

1 reference

12 December 2020

Thrombin functions during tissue factor-induced blood coagulation

1 reference

12 December 2020

Stimulus-induced release of endogenous catecholamines from human washed platelets

1 reference

12 December 2020

Aspirin and dipyridamole in the prevention of restenosis after percutaneous transluminal coronary angioplasty

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12 December 2020

An antibody against the exosite of the cloned thrombin receptor inhibits experimental arterial thrombosis in the African green monkey

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12 December 2020

Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen-deficient mice

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12 December 2020

Identifiers

DOI

10.1093/EURHEARTJ/EHP504

1 reference

21 August 2017

1 reference

21 August 2017

1 reference

PMCID

2800923