TGF-β1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways. (Q37641591)

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scientific article published on 16 August 2016

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English	TGF-β1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways.	scientific article published on 16 August 2016

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21 March 2020

TGF-β1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways (English)

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21 March 2020

endometrial cancer

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inferred from title

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Jung-Chien Cheng

2

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21 March 2020

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Siyuan Xiong

1

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Christian Klausen

3

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21 March 2020

Jianfang Zhao

4

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1 September 2016

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21 March 2020

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21 March 2020

7

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21 March 2020

61262-61272

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21 March 2020

38

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21 March 2020

A phase II evaluation of selumetinib (AZD6244, ARRY-142886), a selective MEK-1/2 inhibitor in the treatment of recurrent or persistent endometrial cancer: an NRG Oncology/Gynecologic Oncology Group study

1 reference

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23 August 2017

Cancer statistics, 2015

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TGF-β: duality of function between tumor prevention and carcinogenesis.

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Emerging therapeutic biomarkers in endometrial cancer

1 reference

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23 August 2017

The functions and regulation of the PTEN tumour suppressor

1 reference

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23 August 2017

Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing

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23 August 2017

Cadherins, catenins and cell cycle regulators: impact on survival in a Gynecologic Oncology Group phase II endometrial cancer trial

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23 August 2017

TGFbeta signaling supports survival and metastasis of endometrial cancer cells.

1 reference

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23 August 2017

Targeting the transforming growth factor-beta signaling pathway in human cancer

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The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells

1 reference

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Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation

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The molecular biology of endometrial cancers and the implications for pathogenesis, classification, and targeted therapies

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Uterine papillary serous and clear cell carcinomas predict for poorer survival compared to grade 3 endometrioid corpus cancers

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Alterations in components of the TGF-beta superfamily signaling pathways in human cancer

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TGF-beta signaling: positive and negative effects on tumorigenesis

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How cells read TGF-beta signals

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Role of Ras and Mapks in TGFbeta signaling

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The role for transforming growth factor-beta (TGF-beta) in human cancer

1 reference

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Loss of growth regulation by transforming growth factor-beta (TGF-beta) in human cancers: studies on endometrial carcinoma

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Regulation of Smad signalling by protein associations and signalling crosstalk

1 reference

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Transforming growth factor-beta in benign and malignant prostate

1 reference

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23 August 2017

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

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23 August 2017

TGF-beta signal transduction

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23 August 2017

Down-regulated expression of transforming growth factor beta 1 mRNA in endometrial carcinoma

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23 August 2017

Two pathogenetic types of endometrial carcinoma

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23 August 2017

Kinases, tails and more: regulation of PTEN function by phosphorylation

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6 September 2017

Current clinical regulation of PI3K/PTEN/Akt/mTOR signalling in treatment of human cancer

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Progesterone inhibits endometrial cancer invasiveness by inhibiting the TGFβ pathway

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Classification of endometrial carcinoma: more than two types

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The activity of letrozole in patients with advanced or recurrent endometrial cancer and correlation with biological markers--a study of the National Cancer Institute of Canada Clinical Trials Group.

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High-risk endometrial carcinoma profiling identifies TGF-β1 as a key factor in the initiation of tumor invasion

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XIAP gene expression and function is regulated by autocrine and paracrine TGF-beta signaling

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14 September 2017

Post-transcriptional and post-translational regulation of PTEN by transforming growth factor-beta1.

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TGFbeta-induced downregulation of E-cadherin-based cell-cell adhesion depends on PI3-kinase and PTEN.

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28 September 2017

Transforming growth factor-beta negatively modulates proliferation and c-fos expression of the human endometrial adenocarcinoma cell line HEC-1-A.

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28 September 2017

Transforming growth factor beta signaling is disabled early in human endometrial carcinogenesis concomitant with loss of growth inhibition.

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Growth and gene expression profile analyses of endometrial cancer cells expressing exogenous PTEN.

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1 September 2018

TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis

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1 September 2018

Endometrial Carcinoma

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3 December 2018

Increased expression of transforming growth factor beta isoforms and basic fibroblast growth factor in complex hyperplasia and adenocarcinoma of the endometrium: evidence for paracrine and autocrine action

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3 December 2018

Expression of transforming growth factor beta 1 by human endometrial carcinoma cell lines: inverse correlation with effects on growth rate and morphology

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12 December 2020

based on heuristic

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The association of transforming growth factor-beta 1 with myometrial invasion of endometrial carcinomas through effects on matrix metalloproteinase

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of PTEN expression is associated with metastatic disease in patients with endometrial carcinoma

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.11311

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21 March 2020

1 reference

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21 March 2020

1 reference

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21 March 2020

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