CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors. (Q37641686)

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scientific article published on 20 August 2016

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English	CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors.	scientific article published on 20 August 2016

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21 March 2020

CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors (English)

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21 March 2020

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Rachel Isaksson Vogel

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21 March 2020

Janeen Trembley

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21 March 2020

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Betsy T Kren

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Gretchen M Unger

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Gretchen M Unger

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21 March 2020

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Khalil Ahmed

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Md Joynal Abedin

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21 March 2020

Daniel P Shaughnessy

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21 March 2020

Lucas Nacusi

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21 March 2020

Vicci L Korman

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21 March 2020

Yingming Li

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21 March 2020

Scott M Dehm

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21 March 2020

Cheryl L Zimmerman

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21 March 2020

Gloria A Niehans

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1 September 2016

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21 March 2020

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21 March 2020

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21 March 2020

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21 March 2020

61789-61805

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21 March 2020

Preclinical Development of a Subcutaneous ALAS1 RNAi Therapeutic for Treatment of Hepatic Porphyrias Using Circulating RNA Quantification

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23 August 2017

Protein kinase CK2α catalytic subunit is overexpressed and serves as an unfavorable prognostic marker in primary hepatocellular carcinoma

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23 August 2017

Tenfibgen-DMAT Nanocapsule Delivers CK2 Inhibitor DMAT to Prostate Cancer Xenograft Tumors Causing Inhibition of Cell Proliferation

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Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy

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23 August 2017

Mining CK2 in cancer

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23 August 2017

Tenfibgen ligand nanoencapsulation delivers bi-functional anti-CK2 RNAi oligomer to key sites for prostate cancer targeting using human xenograft tumors in mice

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23 August 2017

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23 August 2017

Protein kinase CK2 inhibition induces cell death via early impact on mitochondrial function.

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23 August 2017

Mechanism and efficacy of sub-50-nm tenfibgen nanocapsules for cancer cell-directed delivery of anti-CK2 RNAi to primary and metastatic squamous cell carcinoma.

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First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement

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23 August 2017

Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cells

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23 August 2017

Systemic administration of antisense oligonucleotides simultaneously targeting CK2α and α' subunits reduces orthotopic xenograft prostate tumors in mice

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Emergence of protein kinase CK2 as a key target in cancer therapy

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23 August 2017

CK2 modulation of NF-kappaB, TP53, and the malignant phenotype in head and neck cancer by anti-CK2 oligonucleotides in vitro or in vivo via sub-50-nm nanocapsules.

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23 August 2017

Addiction to protein kinase CK2: a common denominator of diverse cancer cells?

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23 August 2017

Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice

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23 August 2017

Protein kinase CK2--a key suppressor of apoptosis

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23 August 2017

Joining the cell survival squad: an emerging role for protein kinase CK2.

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23 August 2017

Protein kinase CK2 signal in neoplasia

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23 August 2017

Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II

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23 August 2017

Association of elevated protein kinase CK2 activity with aggressive behavior of squamous cell carcinoma of the head and neck.

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Clinical experiences with systemically administered siRNA-based therapeutics in cancer

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6 September 2017

CK2α phosphorylates DBC1 and is involved in the progression of gastric carcinoma and predicts poor survival of gastric carcinoma patients

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The role of protein kinase CK2 in intestinal epithelial cell inflammatory signaling

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12 December 2020

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Response of cancer cells to molecular interruption of the CK2 signal

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12 December 2020

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10.18632/ONCOTARGET.11442

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21 March 2020

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21 March 2020

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21 March 2020

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