New insight into the functioning of nitric oxide-receptive guanylyl cyclase: physiological and pharmacological implications (Q37655398)

21 August 2017

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title

New insight into the functioning of nitric oxide-receptive guanylyl cyclase: physiological and pharmacological implications (English)

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21 August 2017

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John Garthwaite

1

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21 August 2017

11 December 2009

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Molecular and Cellular Biochemistry

21 August 2017

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21 August 2017

334

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21 August 2017

1-2

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21 August 2017

221-232

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https://scigraph.springernature.com/pub.10.1007/s11010-009-0318-8

21 August 2017

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cites work

Functional properties of a naturally occurring isoform of soluble guanylyl cyclase

1 reference

https://api.crossref.org/works/10.1007%2FS11010-009-0318-8

Novel complexes of guanylate cyclase with heat shock protein 90 and nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-009-0318-8

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-009-0318-8

Dual effects of intracellular magnesium on muscarinic potassium channel current in single guinea-pig atrial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-009-0318-8

Inhibition of deactivation of NO-sensitive guanylyl cyclase accounts for the sensitizing effect of YC-1.

21 January 2018

1 reference

12 December 2020

Models of the diffusional spread of nitric oxide: implications for neural nitric oxide signalling and its pharmacological properties

1 reference

12 December 2020

Compartmentation of cyclic nucleotide signaling in the heart: the role of cyclic nucleotide phosphodiesterases.

1 reference

12 December 2020

Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes

1 reference

12 December 2020

Rapid nitric oxide-induced desensitization of the cGMP response is caused by increased activity of phosphodiesterase type 5 paralleled by phosphorylation of the enzyme

1 reference

12 December 2020

Fluorescent sensors for rapid monitoring of intracellular cGMP

1 reference

12 December 2020

The receptor-like properties of nitric oxide-activated soluble guanylyl cyclase in intact cells.

1 reference

12 December 2020

Sensitizing soluble guanylyl cyclase to become a highly CO-sensitive enzyme

1 reference

12 December 2020

Properties of NO-activated guanylyl cyclases expressed in cells

1 reference

12 December 2020

Molecular mechanisms involved in the synergistic activation of soluble guanylyl cyclase by YC-1 and nitric oxide in endothelial cells

1 reference

12 December 2020

Guanylyl cyclase/PSD-95 interaction: targeting of the nitric oxide-sensitive alpha2beta1 guanylyl cyclase to synaptic membranes

1 reference

12 December 2020

Probing the presence of the ligand-binding haem in cellular nitric oxide receptors

1 reference

12 December 2020

Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases.

1 reference

12 December 2020

Effect of GTP analogues on purified soluble guanylate cyclase

1 reference

12 December 2020

Effects of the sGC stimulator BAY 41-2272 are not mediated by phosphodiesterase 5 inhibition

1 reference

12 December 2020

BAY41-2272, a novel nitric oxide independent soluble guanylate cyclase activator, relaxes human and rabbit corpus cavernosum in vitro.

1 reference

12 December 2020

Nitric oxide: a unique endogenous signaling molecule in vascular biology

1 reference

12 December 2020

Restoration of the responsiveness of purified guanylate cyclase to nitrosoguanidine, nitric oxide, and related activators by heme and hemeproteins. Evidence for involvement of the paramagnetic nitrosyl-heme complex in enzyme activation

1 reference

12 December 2020

Guanylyl cyclase is an ATP sensor coupling nitric oxide signaling to cell metabolism.

1 reference

12 December 2020

Concepts of neural nitric oxide-mediated transmission

1 reference

12 December 2020

NADPH and heme redox modulate pulmonary artery relaxation and guanylate cyclase activation by NO

1 reference

12 December 2020

Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels

1 reference

12 December 2020

Tonic and acute nitric oxide signaling through soluble guanylate cyclase is mediated by nonheme nitric oxide, ATP, and GTP

1 reference

12 December 2020

Inhibition of phosphodiesterase type 5 by the activator of nitric oxide-sensitive guanylyl cyclase BAY 41-2272.

1 reference

12 December 2020

Design of fluorescence resonance energy transfer (FRET)-based cGMP indicators: a systematic approach

1 reference

12 December 2020

NO-independent regulatory site on soluble guanylate cyclase

1 reference

12 December 2020

Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase

1 reference

12 December 2020

Pharmacology of the nitric oxide receptor, soluble guanylyl cyclase, in cerebellar cells

1 reference

12 December 2020

Direct activation of PDE5 by cGMP: long-term effects within NO/cGMP signaling

1 reference

12 December 2020

Purification and characterization of NO-sensitive guanylyl cyclase

1 reference

12 December 2020

YC-1 facilitates release of the proximal His residue in the NO and CO complexes of soluble guanylate cyclase

1 reference

12 December 2020

Intracellular Mg2+ diffusion within isolated rat skeletal muscle fibers

1 reference

12 December 2020

Biochemistry and pharmacology of novel anthranilic acid derivatives activating heme-oxidized soluble guanylyl cyclase

1 reference

12 December 2020

NO activation of guanylyl cyclase

1 reference

12 December 2020

YC-1, a novel activator of platelet guanylate cyclase

1 reference

12 December 2020

Nitric oxide as a neurotransmitter in peripheral nerves: nature of transmitter and mechanism of transmission

1 reference

12 December 2020

Nitric oxide and macrophage function

1 reference

12 December 2020

Membrane-association and the sensitivity of guanylyl cyclase-coupled receptors to nitric oxide

1 reference

12 December 2020

The interactions of adenylate cyclases with P-site inhibitors

1 reference

12 December 2020

Mutation of His-105 in the beta 1 subunit yields a nitric oxide-insensitive form of soluble guanylyl cyclase

1 reference

12 December 2020

Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase

1 reference

12 December 2020

Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations

1 reference

12 December 2020

In vivo reconstitution of the negative feedback in nitric oxide/cGMP signaling: role of phosphodiesterase type 5 phosphorylation

1 reference

12 December 2020

Calcium-dependent membrane association sensitizes soluble guanylyl cyclase to nitric oxide

1 reference

12 December 2020

An enzyme-linked receptor mechanism for nitric oxide-activated guanylyl cyclase

1 reference

12 December 2020

Identification of residues crucially involved in the binding of the heme moiety of soluble guanylate cyclase

1 reference

12 December 2020

Differential sensitivity of guanylyl cyclase and mitochondrial respiration to nitric oxide measured using clamped concentrations.

1 reference

12 December 2020

[3H]sildenafil binding to phosphodiesterase-5 is specific, kinetically heterogeneous, and stimulated by cGMP.

1 reference

12 December 2020

Unprecedented proximal binding of nitric oxide to heme: implications for guanylate cyclase

1 reference

12 December 2020

A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell

1 reference

12 December 2020

Allosteric activation of cGMP-specific, cGMP-binding phosphodiesterase (PDE5) by cGMP.

1 reference

12 December 2020

Mechanism of muscarinic receptor-induced K+ channel activation as revealed by hydrolysis-resistant GTP analogues

1 reference

12 December 2020

Nitric oxide: physiology, pathophysiology, and pharmacology

1 reference

12 December 2020

NO- and haem-independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principle

1 reference

12 December 2020

Activation of purified soluble guanylate cyclase by protoporphyrin IX.

1 reference

12 December 2020

Kinetics of a cellular nitric oxide/cGMP/phosphodiesterase-5 pathway

1 reference

12 December 2020

AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase

1 reference

12 December 2020

A new and simple method for delivering clamped nitric oxide concentrations in the physiological range: application to activation of guanylyl cyclase-coupled nitric oxide receptors.

1 reference

12 December 2020

Rapid desensitization of the nitric oxide receptor, soluble guanylyl cyclase, underlies diversity of cellular cGMP responses

1 reference

12 December 2020

Phosphodiesterase 5 inhibitors and nitrergic transmission-from zaprinast to sildenafil

1 reference

12 December 2020

NO and CO differentially activate soluble guanylyl cyclase via a heme pivot-bend mechanism

1 reference

12 December 2020

Heat shock protein 90 regulates stabilization rather than activation of soluble guanylate cyclase

1 reference

12 December 2020

Differential patterning of cGMP in vascular smooth muscle cells revealed by single GFP-linked biosensors

1 reference

12 December 2020

Interaction between the 90-kDa heat shock protein and soluble guanylyl cyclase: physiological significance and mapping of the domains mediating binding

1 reference

12 December 2020

YC-1 potentiates nitric oxide- and carbon monoxide-induced cyclic GMP effects in human platelets.

1 reference

12 December 2020

ANF elicits phosphorylation of the cGMP phosphodiesterase in vascular smooth muscle cells

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12 December 2020

Mechanisms of nitric oxide independent activation of soluble guanylyl cyclase

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12 December 2020

Characterization of a novel type of endogenous activator of soluble guanylyl cyclase

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12 December 2020

Dissociation of nitric oxide from soluble guanylate cyclase

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12 December 2020

A Monte Carlo model reveals independent signaling at central glutamatergic synapses

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12 December 2020

Transphosphorylation and G protein activation

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12 December 2020

Dynamics of cellular NO-cGMP signaling

1 reference

12 December 2020

Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one

1 reference

12 December 2020

"cAMP-specific" phosphodiesterase contributes to cGMP degradation in cerebellar cells exposed to nitric oxide.

1 reference

12 December 2020

Cyclic GMP synthesis and function

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12 December 2020

IMP dehydrogenase inhibitors reduce intracellular tetrahydrobiopterin levels through reduction of intracellular GTP levels. Indications of the regulation of GTP cyclohydrolase I activity by restriction of GTP availability in the cells

1 reference

12 December 2020

EPR characterization of axial bond in metal center of native and cobalt-substituted guanylate cyclase

1 reference

12 December 2020

Mechanism of YC-1-induced activation of soluble guanylyl cyclase

1 reference

12 December 2020

Identification of histidine 105 in the beta1 subunit of soluble guanylate cyclase as the heme proximal ligand

1 reference

12 December 2020

Mechanisms of activity-dependent plasticity in cellular nitric oxide-cGMP signaling

1 reference

12 December 2020

Effect of the selective phosphodiesterase type 5 inhibitor sildenafil on erectile dysfunction in the anesthetized dog.

1 reference

12 December 2020

Effects of the soluble guanylyl cyclase activator, YC-1, on vascular tone, cyclic GMP levels and phosphodiesterase activity

1 reference

12 December 2020

The effect of sildenafil on corpus cavernosal smooth muscle relaxation and cyclic GMP formation in the diabetic rabbit

1 reference

12 December 2020

Nitric oxide activation of guanylyl cyclase in cells revisited

1 reference

12 December 2020

Superoxide-dependent consumption of nitric oxide in biological media may confound in vitro experiments

1 reference

12 December 2020

A molecular basis for nitric oxide sensing by soluble guanylate cyclase

1 reference

12 December 2020

A flavoprotein mechanism appears to prevent an oxygen-dependent inhibition of cGMP-associated nitric oxide-elicited relaxation of bovine coronary arteries

1 reference

12 December 2020

Sub-second kinetics of the nitric oxide receptor, soluble guanylyl cyclase, in intact cerebellar cells

1 reference

12 December 2020

The catalytic mechanism of mammalian adenylyl cyclase. Equilibrium binding and kinetic analysis of P-site inhibition

1 reference

12 December 2020

Relaxing effects induced by the soluble guanylyl cyclase stimulator BAY 41-2272 in human and rabbit corpus cavernosum

1 reference

12 December 2020

PDE5 is converted to an activated state upon cGMP binding to the GAF A domain

1 reference

12 December 2020

Evidence for the inhibitory role of guanosine 3', 5'-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators

1 reference

12 December 2020

10.1007/S11010-009-0318-8

Identifiers

DOI

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21 August 2017

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PubMed ID

20012469