CHI3L1 plays a role in cancer through enhanced production of pro-inflammatory/pro-tumorigenic and angiogenic factors (Q37665099)

21 August 2017

CHI3L1 plays a role in cancer through enhanced production of pro-inflammatory/pro-tumorigenic and angiogenic factors (English)

1 reference

21 August 2017

0 references

Stephania Libreros

1

1 reference

21 August 2017

Ramon Garcia-Areas

series ordinal

2

1 reference

21 August 2017

Vijaya Iragavarapu-Charyulu

series ordinal

3

1 reference

21 August 2017

1 December 2013

1 reference

21 August 2017

1 reference

21 August 2017

57

1 reference

21 August 2017

1-3

1 reference

21 August 2017

99-105

1 reference

https://scigraph.springernature.com/pub.10.1007/s12026-013-8459-y

21 August 2017

0 references

cites work

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Chitin microparticles for the control of intestinal inflammation

23 August 2017

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Conditional deletion of Stat3 in mammary epithelium impairs the acute phase response and modulates immune cell numbers during post-lactational regression

23 August 2017

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Chitinase 3-like 1 promotes macrophage recruitment and angiogenesis in colorectal cancer

23 August 2017

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Inhibitory activity of YKL-40 in mammary epithelial cell differentiation and polarization induced by lactogenic hormones: a role in mammary tissue involution

23 August 2017

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Breast cancer expression of YKL-40 correlates with tumour grade, poor differentiation, and other cancer markers

23 August 2017

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Overexpression of chitinase 3-like 1/YKL-40 in lung-specific IL-18-transgenic mice, smokers and COPD

23 August 2017

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Induction of proinflammatory mediators by CHI3L1 is reduced by chitin treatment: decreased tumor metastasis in a breast cancer model

23 August 2017

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Expression of the inflammatory chemokines CCL2, CCL5 and CXCL2 and the receptors CCR1-3 and CXCR2 in T lymphocytes from mammary tumor-bearing mice

23 August 2017

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Role of YKL-40 in the angiogenesis, radioresistance, and progression of glioblastoma

23 August 2017

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A YKL-40-neutralizing antibody blocks tumor angiogenesis and progression: a potential therapeutic agent in cancers

23 August 2017

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Chemokines and chemokine receptors: new insights into cancer-related inflammation.

23 August 2017

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Potential role of chitinase 3-like-1 in inflammation-associated carcinogenic changes of epithelial cells

23 August 2017

1 reference

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Human chitinases and chitinase-like proteins as indicators for inflammation and cancer

23 August 2017

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Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis

23 August 2017

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Serum YKL-40 and interleukin 6 levels in Hodgkin lymphoma

23 August 2017

1 reference

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YKL-40, a marker of simian immunodeficiency virus encephalitis, modulates the biological activity of basic fibroblast growth factor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Inflammatory bowel disease, past, present and future: lessons from animal models

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

A chitinase-like protein in the lung and circulation of patients with severe asthma

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Studies on serum YKL-40 as a biomarker in diseases with inflammation, tissue remodelling, fibroses and cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

YKL-40, a new inflammatory marker with relation to insulin resistance and with a role in endothelial dysfunction and atherosclerosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Serum YKL-40, a new prognostic biomarker in cancer patients?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

High serum YKL-40 levels in patients with primary breast cancer is related to short recurrence free survival

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

23 August 2017

Inflammation and cancer

1 reference

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The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways

23 August 2017

1 reference

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Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

23 August 2017

1 reference

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Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

23 August 2017

1 reference

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Identification of a novel acidic mammalian chitinase distinct from chitotriosidase

23 August 2017

1 reference

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MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

23 August 2017

1 reference

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Chitinases of human parasites and their implications as antiparasitic targets

23 August 2017

1 reference

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Serum YKL-40 concentrations in patients with rheumatoid arthritis: relation to disease activity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Matrix-degrading proteases and angiogenesis during development and tumor formation.

23 August 2017

1 reference

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Serum YKL-40 and colorectal cancer.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Molecular characterization of the gene for human cartilage gp-39 (CHI3L1), a member of the chitinase protein family and marker for late stages of macrophage differentiation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Differential screening identifies genetic markers of monocyte to macrophage maturation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Antibiotics that inhibit fungal cell wall development

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Human synovial cells secrete a 39 kDa protein similar to a bovine mammary protein expressed during the non-lactating period

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

YKL-40 induces IL-8 expression from bronchial epithelium via MAPK (JNK and ERK) and NF-κB pathways, causing bronchial smooth muscle proliferation and migration

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Identification of a 38-kDa heparin-binding glycoprotein (gp38k) in differentiating vascular smooth muscle cells as a member of a group of proteins associated with tissue remodeling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

The chitin crystallite in arthropod cuticle

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

YKL-40, a secreted glycoprotein, promotes tumor angiogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

YKL-40 is elevated in patients with chronic obstructive pulmonary disease and activates alveolar macrophages

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Chitinase 3-like-1 enhances bacterial adhesion to colonic epithelial cells through the interaction with bacterial chitin-binding protein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

YKL-40 expression could be a poor prognostic marker in the breast cancer tissue

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

YKL-40 (cartilage gp-39) induces proliferative events in cultured chondrocytes and synoviocytes and increases glycosaminoglycan synthesis in chondrocytes

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

A new biochemical marker for joint injury. Analysis of YKL-40 in serum and synovial fluid.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Chitin synthesis and sheath morphogenesis in Brugia malayi microfilariae.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Serum YKL-40 as a marker for cervical adenocarcinoma.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

The mammalian chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Prostatic cancer 2006--status and new challenges. The Danish Society of Urology

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Chitinase 3-like-1 exacerbates intestinal inflammation by enhancing bacterial adhesion and invasion in colonic epithelial cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Elevated serum level of YKL-40 is an independent prognostic factor for poor survival in patients with metastatic melanoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

YKL-40 expression is associated with poorer response to radiation and shorter overall survival in glioblastoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Increased serum YKL-40 in patients with pulmonary sarcoidosis--a potential marker of disease activity?

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Early detection and prognosis of ovarian cancer using serum YKL-40.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Up-Regulation of Matrix Metalloproteinase-9 in T Lymphocytes of Mammary Tumor Bearers: Role of Vascular Endothelial Growth Factor

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Transglycosidase activity of chitotriosidase: improved enzymatic assay for the human macrophage chitinase.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Oral administration of chitin down-regulates serum IgE levels and lung eosinophilia in the allergic mouse.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Gp38k, a protein synthesized by vascular smooth muscle cells, stimulates directional migration of human umbilical vein endothelial cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

neu and ras initiate murine mammary tumors that share genetic markers generally absent in c-myc and int-2-initiated tumors.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Preoperative serum YKL-40 is a marker for detection and prognosis of endometrial cancer

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12026-013-8459-Y

High plasma YKL-40 level in patients with ovarian cancer stage III is related to shorter survival

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966554

Experimental anti-angiogenesis causes upregulation of genes associated with poor survival in glioblastoma

3 December 2018

1 reference

12 December 2020

Plasma YKL-40: a new potential marker of fibrosis in patients with alcoholic cirrhosis?

1 reference

12 December 2020

High serum YKL-40 level in patients with small cell lung cancer is related to early death

1 reference

12 December 2020

Locally advanced breast carcinoma treated with neoadjuvant chemotherapy: are the changes in serum levels of YKL-40, MMP-2 and MMP-9 correlated with tumor response?

1 reference

12 December 2020

Chitin particle-induced cell-mediated immunity is inhibited by soluble mannan: mannose receptor-mediated phagocytosis initiates IL-12 production

1 reference

12 December 2020

Prognostic value of PINP, bone alkaline phosphatase, CTX-I, and YKL-40 in patients with metastatic prostate carcinoma

1 reference

12 December 2020

High serum concentration of YKL-40 is associated with short survival in patients with acute myeloid leukemia

1 reference

12 December 2020

Serum YKL-40, a potential new marker of disease activity in patients with inflammatory bowel disease

1 reference

12 December 2020

Serum YKL-40 is increased in patients with hepatic fibrosis

1 reference

12 December 2020

Increased expression of the inflammatory protein YKL-40 in precancers of the breast

1 reference

12 December 2020

Chitinase 3-Like-1 (CHI3L1): a putative disease marker at the interface of proteomics and glycomics

1 reference

12 December 2020

YKL-40 and MMP-9 as serum markers for patients with primary central nervous system lymphoma

1 reference

12 December 2020

Cytochemical localization of carbohydrate residues in microfilariae of Wuchereria bancrofti and Brugia malayi

1 reference

12 December 2020

Serum YKL-40: A new potential marker of prognosis and location of métastases of patients with recurrent breast cancer

1 reference

12 December 2020

High levels of serum HER-2/neu and YKL-40 independently reflect aggressiveness of metastatic breast cancer

1 reference

12 December 2020

10.1007/S12026-013-8459-Y

Identifiers

DOI

1 reference

21 August 2017

1 reference

21 August 2017

PubMed publication ID

24222276

1 reference