The mammalian chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation. (Q53622506)

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English	The mammalian chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation.	scientific article

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scholarly article

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16704970

The mammalian chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation. (English)

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16704970

Chitinase 3 like 1

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author name string

Heather F Bigg

1

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16704970

Robin Wait

2

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16704970

Andrew D Rowan

3

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16704970

Tim E Cawston

4

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16704970

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publication date

15 May 2006

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16704970

Journal of Biological Chemistry

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16704970

281

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16704970

21082-21095

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16704970

30

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16704970

Human synovial cells secrete a 39 kDa protein similar to a bovine mammary protein expressed during the non-lactating period

1 reference

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Purification of guinea pig YKL40 and modulation of its secretion by cultured articular chondrocytes

1 reference

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Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39

1 reference

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Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes

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Crystal structure of a novel regulatory 40-kDa mammary gland protein (MGP-40) secreted during involution

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A new biochemical marker for joint injury. Analysis of YKL-40 in serum and synovial fluid.

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Regulation of YKL-40 production by human articular chondrocytes

1 reference

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Identification of a 38-kDa heparin-binding glycoprotein (gp38k) in differentiating vascular smooth muscle cells as a member of a group of proteins associated with tissue remodeling

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Induction and expression of human cartilage glycoprotein 39 in rheumatoid inflammatory and peripheral blood monocyte-derived macrophages

1 reference

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Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages

1 reference

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Purification and characterization of human chitotriosidase, a novel member of the chitinase family of proteins

1 reference

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Structure of human chitotriosidase. Implications for specific inhibitor design and function of mammalian chitinase-like lectins

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Isolation and sequence of a novel human chondrocyte protein related to mammalian members of the chitinase protein family

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A macrophage protein, Ym1, transiently expressed during inflammation is a novel mammalian lectin.

1 reference

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The crystal structure of a novel mammalian lectin, Ym1, suggests a saccharide binding site

1 reference

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21 January 2018

Identification of a novel acidic mammalian chitinase distinct from chitotriosidase

1 reference

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Characterization and biological roles of oviduct-specific, oestrogen-dependent glycoprotein

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Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway

1 reference

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Structural and sequence-based classification of glycoside hydrolases

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Crystal structures of hevamine, a plant defence protein with chitinase and lysozyme activity, and its complex with an inhibitor

1 reference

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Crystal structure of a bacterial chitinase at 2.3 A resolution

1 reference

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21 January 2018

Structure of a two-domain chitotriosidase from Serratia marcescens at 1.9-A resolution

1 reference

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21 January 2018

Structural insights into the catalytic mechanism of a family 18 exo-chitinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601153200

21 January 2018

High resolution structural analyses of mutant chitinase A complexes with substrates provide new insight into the mechanism of catalysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601153200

21 January 2018

Expression and characterization of active site mutants of hevamine, a chitinase from the rubber tree Hevea brasiliensis

1 reference

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21 January 2018

Stereochemistry of chitin hydrolysis by a plant chitinase/lysozyme and X-ray structure of a complex with allosamidin: evidence for substrate assisted catalysis

1 reference

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Serum YKL-40 levels in healthy children and adults. Comparison with serum and synovial fluid levels of YKL-40 in patients with osteoarthritis or trauma of the knee joint.

1 reference

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21 January 2018

Serum YKL-40 and colorectal cancer.

1 reference

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High serum YKL-40 level after surgery for colorectal carcinoma is related to short survival

1 reference

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Serum YKL-40 concentrations in patients with rheumatoid arthritis: relation to disease activity

1 reference

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Differential MHC class II-mediated presentation of rheumatoid arthritis autoantigens by human dendritic cells and macrophages.

1 reference

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Human cartilage glycoprotein 39 (HC gp-39) mRNA expression in adult and fetal chondrocytes, osteoblasts and osteocytes by in-situ hybridization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601153200

21 January 2018

Homologs of the Xenopus developmental gene DG42 are present in zebrafish and mouse and are involved in the synthesis of Nod-like chitin oligosaccharides during early embryogenesis

1 reference

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21 January 2018

Cells expressing the DG42 gene from early Xenopus embryos synthesize hyaluronan

1 reference

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21 January 2018

Does DG42 synthesize hyaluronan or chitin?: A controversy about oligosaccharides in vertebrate development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601153200

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YKL-40 (cartilage gp-39) induces proliferative events in cultured chondrocytes and synoviocytes and increases glycosaminoglycan synthesis in chondrocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601153200

21 January 2018

The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601153200

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Gp38k, a protein synthesized by vascular smooth muscle cells, stimulates directional migration of human umbilical vein endothelial cells.

1 reference

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gp38k (CHI3L1) is a novel adhesion and migration factor for vascular cells

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The chitinase 3-like protein human cartilage glycoprotein 39 inhibits cellular responses to the inflammatory cytokines interleukin-1 and tumour necrosis factor-alpha

1 reference

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Stabilisation of purified human collagenase by site-directed mutagenesis.

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Proteins of rat serum, urine, and cerebrospinal fluid: VI. Further protein identifications and interstrain comparison

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Strategies for proteomics with incompletely characterized genomes: the proteome of Bos taurus serum

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A rapid and reproducible assay for collagenase using [1-14C]acetylated collagen

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The prevention of collagen breakdown in bovine nasal cartilage by TIMP, TIMP-2 and a low molecular weight synthetic inhibitor.

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Collagen fibril formation

1 reference

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Collagen fibril biosynthesis in tendon: a review and recent insights.

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PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1

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Inflammatory cytokines induce production of CHI3L1 by articular chondrocytes

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Substrate-Assisted Catalysis Unifies Two Families of Chitinolytic Enzymes

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In vitro expression of a 38,000 dalton heparin-binding glycoprotein by morphologically differentiated smooth muscle cells

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Isolation and characterization of a novel 39 kilodalton whey protein from bovine mammary secretions collected during the nonlactating period

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The distribution of YKL-40 in osteoarthritic and normal human articular cartilage

1 reference

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Studies on YKL-40 in knee joints of patients with rheumatoid arthritis and osteoarthritis. Involvement of YKL-40 in the joint pathology

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Serum YKL-40: a new potential marker of prognosis and location of metastases of patients with recurrent breast cancer

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Plasma YKL-40: a new potential marker of fibrosis in patients with alcoholic cirrhosis?

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The relationship between serum levels of YKL-40 and disease progression in patients with early rheumatoid arthritis

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Interleukin-1 and oncostatin M in combination promote the release of collagen fragments from bovine nasal cartilage in culture

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Characterization of folded, intermediate, and unfolded states of recombinant human interstitial collagenase

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96-Well plate assays for measuring collagenase activity using (3)H-acetylated collagen

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Fragments of human fibroblast collagenase: interaction with metalloproteinase inhibitors and substrates

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Induction of interleukin-1 in articular cartilage by explantation and cutting

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Identifiers

10.1074/JBC.M601153200

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16704970

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16704970

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