Molecular mechanisms underlying nutrient-stimulated incretin secretion (Q37667168)

21 August 2017

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title

Molecular mechanisms underlying nutrient-stimulated incretin secretion (English)

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21 August 2017

Frank Reimann

2

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Fiona Gribble

object named as

Fiona M Gribble

series ordinal

3

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author name string

Helen E Parker

series ordinal

1

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21 August 2017

5 January 2010

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Expert Reviews in Molecular Medicine

21 August 2017

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21 August 2017

12

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21 August 2017

e1

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Glucokinase, the pancreatic glucose sensor, is not the gut glucose sensor

21 August 2017

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Familial hyperinsulinism caused by an activating glucokinase mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Regulation of pancreatic beta-cell glucokinase: from basics to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Glucose-sensing in glucagon-like peptide-1-secreting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Glucose sensing in L cells: a primary cell study

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Fetal rat intestinal cells in monolayer culture: a new in vitro system to study the glucagon-like immunoreactive peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Aberrant regulation of human intestinal proglucagon gene expression in the NCI-H716 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Glucose-dependent insulin release from genetically engineered K cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Novel insulin/GIP co-producing cell lines provide unexpected insights into Gut K-cell function in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Regulation of glucagon-like peptide-1 synthesis and secretion in the GLUTag enteroendocrine cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Bitter stimuli induce Ca2+ signaling and CCK release in enteroendocrine STC-1 cells: role of L-type voltage-sensitive Ca2+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Taste-signaling proteins are coexpressed in solitary intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Meat hydrolysate and essential amino acid-induced glucagon-like peptide-1 secretion, in the human NCI-H716 enteroendocrine cell line, is regulated by extracellular signal-regulated kinase1/2 and p38 mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Peptones stimulate both the secretion of the incretin hormone glucagon-like peptide 1 and the transcription of the proglucagon gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Regulation of cholecystokinin secretion by peptones and peptidomimetic antibiotics in STC-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Effects of fluoroquinolones on insulin secretion and beta-cell ATP-sensitive K+ channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Short-chain fatty acid release of peptide YY in the isolated rabbit distal colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Luminal glucagon-like peptide-1(7-36) amide-releasing factors in the isolated vascularly perfused rat colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Medium-chain fatty acids as ligands for orphan G protein-coupled receptor GPR84

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Free fatty acids induce cholecystokinin secretion through GPR120.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

The effects of duodenal peptides on glucagon-like peptide-1 secretion from the ileum. A duodeno--ileal loop?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Gastric emptying and release of incretin hormones after glucose ingestion in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Bitter taste receptors influence glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

The neurotransmitters glycine and GABA stimulate glucagon-like peptide-1 release from the GLUTag cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Possible role of PEPT1 in gastrointestinal hormone secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Cholecystokinin increases cytosolic calcium in a subpopulation of cultured vagal afferent neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Cholecystokinin activates both A- and C-type vagal afferent neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Glucagon-like peptide-1 evokes action potentials and increases cytosolic Ca2+ in rat nodose ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Control of glucagon-like immunoreactive peptide secretion from fetal rat intestinal cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Cyclic AMP triggers glucagon-like peptide-1 secretion from the GLUTag enteroendocrine cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Protein kinase Czeta is required for oleic acid-induced secretion of glucagon-like peptide-1 by intestinal endocrine L cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Orlistat accelerates gastric emptying and attenuates GIP release in healthy subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Effect of lipase inhibition on gastric emptying of, and the glycemic and incretin responses to, an oil/aqueous drink in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Functional GIP receptors are present on adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

GIP biology and fat metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

The G-protein-coupled receptor 40 family (GPR40-GPR43) and its role in nutrient sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Dipeptidyl-peptidase IV (CD26)--role in the inactivation of regulatory peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Type 2 diabetes--therapy with dipeptidyl peptidase IV inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Glucagon-like peptide 1(GLP-1) in biology and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

The Physiology of Glucagon-like Peptide 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Biology of incretins: GLP-1 and GIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

The incretin concept today

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

A centenary of gastrointestinal endocrinology

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

On the treatment of Diabetus mellitus by acid extract of Duodenal Mucous Membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

The [pre-] history of the incretin concept

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Electronimmunocytochemical evidence for the K cell localization of gastric inhibitory polypeptide (GIP) im man

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Sweetness and bitterness taste of meals per se does not mediate gastric emptying in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Cellular localization of gastric inhibitory polypeptide in the duodenum and jejunum

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Expression of sweet taste receptors of the T1R family in the intestinal tract and enteroendocrine cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Taste receptor signaling in the mammalian gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

A G protein-coupled receptor responsive to bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

A role for intestinal endocrine cell-expressed g protein-coupled receptor 119 in glycemic control by enhancing glucagon-like Peptide-1 and glucose-dependent insulinotropic Peptide release

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

GPR119 is required for physiological regulation of glucagon-like peptide-1 secretion but not for metabolic homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Glycoside binding and translocation in Na(+)-dependent glucose cotransporters: comparison of SGLT1 and SGLT3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Dissociation between sensing and metabolism of glucose in sugar sensing neurones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

The sodium/glucose cotransport family SLC5

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Glucagon-like peptide-1 secretion is influenced by perfusate glucose concentration and by a feedback mechanism involving somatostatin in isolated perfused porcine ileum

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Hyperglycemia acutely lowers the postprandial excursions of glucagon-like Peptide-1 and gastric inhibitory polypeptide in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Gastric Inhibitory Polypeptide Enhanced Lipoprotein Lipase Activity in Cultured Preadipocytes

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

A human cellular model for studying the regulation of glucagon-like peptide-1 secretion

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

PLASMA INSULIN RESPONSE TO ORAL AND INTRAVENOUS GLUCOSE ADMINISTRATION

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine.

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Glucagon-like-peptide-1 secretion from canine L-cells is increased by glucose-dependent-insulinotropic peptide but unaffected by glucose

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Regulation of intestinal proglucagon-derived peptide secretion by glucose-dependent insulinotropic peptide in a novel enteroendocrine loop

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Gastric inhibitory polypeptide (GIP) stimulation by oral glucose in man

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Gastrin-releasing peptide is a novel mediator of proximal nutrient-induced proglucagon-derived peptide secretion from the distal gut

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Biological effects and metabolic rates of glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 in healthy subjects are indistinguishable

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Release of glucagon-like peptide-1 (GLP-1) by carbohydrates in the perfused rat ileum

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Stimulation of glucagon-like peptide-1 secretion by muscarinic agonist in a murine intestinal endocrine cell line

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Investigation of Structure-Activity Relationships of Oxyntomodulin (Oxm) Using Oxm Analogs

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Muscarinic receptors control postprandial release of glucagon-like peptide-1: in vivo and in vitro studies in rats

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Interactions of a series of fluoroquinolone antibacterial drugs with the human cardiac K+ channel HERG.

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Peptide YY, glucagon-like peptide-1, and neurotensin responses to luminal factors in the isolated vascularly perfused rat ileum

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Evidence for preferential stimulation of gastric inhibitory polypeptide secretion in the rat by actively transported carbohydrates and their analogues

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

Somatostatin restrains the secretion of glucagon-like peptide-1 and -2 from isolated perfused porcine ileum

1 reference

https://api.crossref.org/works/10.1017%2FS146239940900132X

7 January 2021

10.1017/S146239940900132X

Identifiers

DOI

1 reference

21 August 2017

1 reference

PubMed ID

20047700