Adiponectin inhibits insulin function in primary trophoblasts by PPARα-mediated ceramide synthesis. (Q37670103)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24606127%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Adiponectin inhibits insulin function in primary trophoblasts by PPARα-mediated ceramide synthesis (English)

1 reference

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9 March 2020

1 reference

1 reference

5

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9 March 2020

Irving Aye

1

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9 March 2020

author name string

Xiaoli Gao

2

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9 March 2020

Susan T Weintraub

3

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9 March 2020

Thomas Jansson

4

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9 March 2020

publication date

25 February 2014

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9 March 2020

published in

Molecular Endocrinology

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9 March 2020

volume

28

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9 March 2020

issue

4

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9 March 2020

page(s)

512-524

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Placental transport in response to altered maternal nutrition

9 March 2020

cites work

1 reference

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Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino Acid transport in human primary trophoblast cells

23 August 2017

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23 August 2017

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Insulin and the IGF system in the human placenta of normal and diabetic pregnancies

23 August 2017

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Fetuses of obese mothers develop insulin resistance in utero

23 August 2017

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Ceramide starves cells to death by downregulating nutrient transporter proteins

23 August 2017

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23 August 2017

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23 August 2017

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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

23 August 2017

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23 August 2017

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23 August 2017

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6 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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SB203580, a pharmacological inhibitor of p38 MAP kinase transduction pathway activates ERK and JNK MAP kinases in primary cultures of human hepatocytes.

14 September 2017

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14 September 2017

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14 September 2017

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Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells

28 September 2017

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Sphingosine-sphingosine-1-phosphate pathway regulates trophoblast differentiation and syncytialization.

25 June 2018

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Cross talk between cAMP and p38 MAPK pathways in the induction of leptin by hCG in human placental syncytiotrophoblasts

25 June 2018

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Leptin and adiponectin stimulate the release of proinflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via nuclear factor-kappaB, peroxisomal proliferator-activated receptor-gamma and extracellularly regulated k

25 June 2018

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PPAR activation as a regulator of lipid metabolism, nitric oxide production and lipid peroxidation in the placenta from type 2 diabetic patients.

25 June 2018

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Lipidomic analysis of human placental syncytiotrophoblast microvesicles in adverse pregnancy outcomes.

1 September 2018

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Phosphoprotein Phosphatase PP2A Regulation of Insulin Receptor Substrate 1 and Insulin Metabolic Signaling

1 September 2018

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Ceramide biosynthesis and metabolism in trophoblast syncytialization.

1 September 2018

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Chronic maternal infusion of full-length adiponectin in pregnant mice down-regulates placental amino acid transporter activity and expression and decreases fetal growth

1 September 2018

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Hypertonic stress regulates amino acid transport and cell cycle proteins in chick embryo hepatocytes

1 September 2018

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A high-fat diet reduces ceramide synthesis by decreasing adiponectin levels and decreases lipid content by modulating HMG-CoA reductase and CPT-1 mRNA expression in the skin.

1 September 2018

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Activation of PPARα by bezafibrate negatively affects de novo synthesis of sphingolipids in regenerating rat liver

1 September 2018

1 reference

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Regulation of amino acid transporters by glucose and growth factors in cultured primary human trophoblast cells is mediated by mTOR signaling.

1 September 2018

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Ultra-low dose naloxone restores the antinociceptive effect of morphine in pertussis toxin-treated rats and prevents glutamate transporter downregulation by suppressing the p38 mitogen-activated protein kinase signaling pathway.

1 September 2018

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Maternal hormones linking maternal body mass index and dietary intake to birth weight

1 September 2018

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ERK1/2 and p38 regulate trophoblasts differentiation in human term placenta.

1 September 2018

1 reference

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Intrauterine growth restriction in humans is associated with abnormalities in placental insulin-like growth factor signaling

1 September 2018

1 reference

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Fumonisins: fungal toxins that shed light on sphingolipid function.

1 September 2018

1 reference

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Inhibitory effect of ceramide on insulin-induced protein kinase Czeta translocation in rat adipocytes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3968401

Purification, Characterization, andin vitroDifferentiation of Cytotrophoblasts from Human Term Placentae*

1 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3968401

Maternal serum adiponectin levels during human pregnancy

3 December 2018

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12 December 2020

Ceramide mediates TNF-α-induced insulin resistance on GLUT4 gene expression in brown adipocytes

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12 December 2020

Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha

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12 December 2020

Activation of the nuclear receptor PPARα regulates lipid metabolism in foetal liver from diabetic rats: implications in diabetes-induced foetal overgrowth

1 reference

12 December 2020

PPARalpha agonist induces the accumulation of ceramide in the heart of rats fed high-fat diet

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12 December 2020

Identifiers

DOI

10.1210/ME.2013-1401

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24606127%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24606127%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24606127%20AND%20SRC:MED&resulttype=core&format=json