Gatekeepers of intestinal inflammation (Q37672486)

21 August 2017

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title

Gatekeepers of intestinal inflammation (English)

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21 August 2017

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Heather A Arnett

1

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21 August 2017

Joanne L Viney

series ordinal

2

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21 August 2017

publication date

1 January 2010

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21 August 2017

published in

Inflammation Research

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21 August 2017

volume

59

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21 August 2017

issue

1

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21 August 2017

page(s)

1-14

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Stochastic monoallelic expression of IL-10 in T cells

21 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

In situ expression of interleukin-10 in noninflamed human gut and in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

Association of polymorphic alleles of CTLA4 with inflammatory bowel disease in the Japanese

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

No association of the cytotoxic T-lymphocyte associated gene CTLA4 +49A/G polymorphisms with Crohn's disease and ulcerative colitis in Hungarian population samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

Blockade of B7-H1 Suppresses the Development of Chronic Intestinal Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

Evolutionary study of multigenic families mapping close to the human MHC class I region

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

The B7 homolog butyrophilin BTN2A1 is a novel ligand for DC-SIGN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

BTNL2, a butyrophilin-like molecule that functions to inhibit T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

Neutrophil-derived defensins as modulators of innate immune function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

Different cytokine response of primary colonic epithelial cells to commensal bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

Probiotics ameliorate recurrent Th1-mediated murine colitis by inducing IL-10 and IL-10-dependent TGF-beta-bearing regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00011-009-0091-X

Immunoregulatory role of interleukin 10 in patients with inflammatory bowel disease

21 January 2018

1 reference

12 December 2020

MHC fine mapping of human type 1 diabetes using the T1DGC data

1 reference

12 December 2020

No association of polymorphisms of the CTLA-4 exon 1(+49) and promoter(-318) genes with rheumatoid arthritis in the Korean population

1 reference

12 December 2020

Interleukin-10 gene knock-out mice: a model of chronic inflammation.

1 reference

12 December 2020

Anti-inflammatory effects of probiotic yogurt in inflammatory bowel disease patients

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12 December 2020

Lactic acid bacteria inhibit proinflammatory cytokine expression and bacterial glycosaminoglycan degradation activity in dextran sulfate sodium-induced colitic mice

1 reference

12 December 2020

GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.

1 reference

12 December 2020

Association of the BTNL2 rs2076530 single nucleotide polymorphism with Graves' disease appears to be secondary to DRB1 exon 2 position beta74

1 reference

12 December 2020

Altered immune responses in interleukin 10 transgenic mice

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12 December 2020

Towards a cure for food allergy

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12 December 2020

Gastrointestinal dendritic cells play a role in immunity, tolerance, and disease

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12 December 2020

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

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12 December 2020

Tryptophan metabolism and indoleamine 2,3-dioxygenase expression in coeliac disease

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12 December 2020

Reduced Paneth cell alpha-defensins in ileal Crohn's disease

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12 December 2020

Association of CTLA4 gene A-G polymorphism with rheumatoid arthritis in Chinese

1 reference

12 December 2020

Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4

1 reference

12 December 2020

IDO expression by dendritic cells: tolerance and tryptophan catabolism

1 reference

12 December 2020

Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

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12 December 2020

Interactions among dendritic cells, macrophages, and epithelial cells in the gut: implications for immune tolerance.

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12 December 2020

Differential distribution of B7.1 (CD80) and B7.2 (CD86) costimulatory molecules on mucosal macrophage subsets in human inflammatory bowel disease (IBD)

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12 December 2020

Tuning microenvironments: induction of regulatory T cells by dendritic cells

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12 December 2020

Anatomical basis of tolerance and immunity to intestinal antigens

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12 December 2020

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

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12 December 2020

Interleukin-10-deficient mice develop chronic enterocolitis

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12 December 2020

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

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12 December 2020

Altered Th1/Th2 cytokine profiles in the intestinal mucosa of patients with inflammatory bowel disease as assessed by quantitative reversed transcribed polymerase chain reaction (RT-PCR)

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12 December 2020

Oral feeding of Bifidobacterium bifidum (BGN4) prevents CD4(+) CD45RB(high) T cell-mediated inflammatory bowel disease by inhibition of disordered T cell activation

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12 December 2020

Sarcoidosis is associated with a truncating splice site mutation in BTNL2.

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12 December 2020

CD103+ GALT DCs promote Foxp3+ regulatory T cells

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12 December 2020

Chemokines and chemokine receptors in mucosal homeostasis at the intestinal epithelial barrier in inflammatory bowel disease

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12 December 2020

Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12

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12 December 2020

Analysis of BTNL2 genetic polymorphisms in British and Dutch patients with sarcoidosis

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12 December 2020

The fundamental basis of inflammatory bowel disease

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12 December 2020

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

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12 December 2020

Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells

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12 December 2020

Prevention of allogeneic fetal rejection by tryptophan catabolism

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12 December 2020

Extended genetic analysis of BTNL2 in sarcoidosis

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12 December 2020

NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

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12 December 2020

IL-23 and Th17 cytokines in intestinal homeostasis

1 reference

12 December 2020

Genetic impact of a butyrophilin-like 2 (BTNL2) gene variation on specific IgE responsiveness to Dermatophagoides farinae (Der f) in Japanese

1 reference

12 December 2020

Lymphocyte homing and its role in the pathogenesis of IBD.

1 reference

12 December 2020

Expanding dendritic cells in vivo enhances the induction of oral tolerance

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12 December 2020

Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells

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12 December 2020

Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses

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12 December 2020

Butyrophilin-like 2 gene is associated with ulcerative colitis in the Japanese under strong linkage disequilibrium with HLA-DRB1*1502.

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12 December 2020

The mechanism of anti-CTLA-4 activity and the negative regulation of T-cell activation

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12 December 2020

Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

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12 December 2020

Identification of the predominant antigenic epitopes in intestinal flora in IBD.

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12 December 2020

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

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12 December 2020

GWA studies: rewriting the story of IBD.

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12 December 2020

A focus on dendritic cells and macrophages as key regulators of mucosal immunity

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12 December 2020

New players in the cytokine orchestra of inflammatory bowel disease

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12 December 2020

The CTLA4 +49 A/G*G-CT60*G haplotype is associated with susceptibility to multiple sclerosis in Flanders

1 reference

12 December 2020

Barrier dysfunction due to distinct defensin deficiencies in small intestinal and colonic Crohn's disease

1 reference

12 December 2020

Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease. Crohn's Disease IL-10 Cooperative Study Group

1 reference

12 December 2020

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

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12 December 2020

Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?

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12 December 2020

BTNL2 allele associations with chronic beryllium disease in HLA-DPB1*Glu69-negative individuals

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12 December 2020

Regulation of costimulation in the era of butyrophilins

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12 December 2020

The ins and outs of body surface immunology

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12 December 2020

Deficiency of indoleamine 2,3-dioxygenase enhances commensal-induced antibody responses and protects against Citrobacter rodentium-induced colitis

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12 December 2020

Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship

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12 December 2020

Mucosal dendritic cells in immunity and inflammation

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12 December 2020

Chronic colitis in IL-10-/- mice: insufficient counter regulation of a Th1 response.

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12 December 2020

Regulation of mucosal dendritic cell function by receptor activator of NF-kappa B (RANK)/RANK ligand interactions: impact on tolerance induction

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12 December 2020

Tissue expression of PD-L1 mediates peripheral T cell tolerance.

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12 December 2020

Association of the truncating splice site mutation in BTNL2 with multiple sclerosis is secondary to HLA-DRB1*15.

1 reference

12 December 2020

Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease.

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12 December 2020

Allelic variation in BTNL2 and susceptibility to tuberculosis in a South African population

1 reference

12 December 2020

Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn's disease. Crohn's Disease Study Group

1 reference

12 December 2020

The cluster of BTN genes in the extended major histocompatibility complex

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12 December 2020

T-cell co-stimulatory molecules are upregulated on intestinal macrophages from inflammatory bowel disease mucosa

1 reference

12 December 2020

Interleukin 10 suppresses experimental chronic, granulomatous inflammation induced by bacterial cell wall polymers

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12 December 2020

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

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12 December 2020

Histopathological evaluation of colonic mucosal biopsy specimens in chronic inflammatory bowel disease: diagnostic implications

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12 December 2020

Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system

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12 December 2020

Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene.

1 reference

12 December 2020

Treatment of murine colitis by Lactococcus lactis secreting interleukin-10.

1 reference

12 December 2020

Inhibition of T cell proliferation by macrophage tryptophan catabolism

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12 December 2020

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

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12 December 2020

Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor

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12 December 2020

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

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12 December 2020

CTLA-4 control over Foxp3+ regulatory T cell function

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12 December 2020

Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse

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12 December 2020

BTL-II: a polymorphic locus with homology to the butyrophilin gene family, located at the border of the major histocompatibility complex class II and class III regions in human and mouse.

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12 December 2020

CTLA-4-Ig regulates tryptophan catabolism in vivo.

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12 December 2020

Role of cytokines in inflammatory bowel disease

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12 December 2020

Patients with inflammatory bowel disease may have a transforming growth factor-beta-, interleukin (IL)-2- or IL-10-deficient state induced by intrinsic neutralizing antibodies

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12 December 2020

Mucosal CD8alpha+ DC, with a plasmacytoid phenotype, induce differentiation and support function of T cells with regulatory properties

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12 December 2020

Overexpression of indoleamine 2,3-dioxygenase in human inflammatory bowel disease

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12 December 2020

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

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12 December 2020

T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.

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12 December 2020

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1 reference

12 December 2020

The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locus.

1 reference

12 December 2020

CTLA4 polymorphisms and ophthalmopathy in Graves' disease patients: association study and meta-analysis.

1 reference

12 December 2020

Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin

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12 December 2020

PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells

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12 December 2020

T cell apoptosis by tryptophan catabolism

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12 December 2020

Abatacept in the treatment of rheumatoid arthritis

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12 December 2020

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

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12 December 2020

Analysis of cytotoxic T lymphocyte associated antigen 4 gene polymorphisms in patients with ulcerative colitis

1 reference

12 December 2020

Unique functions of CD11b+, CD8 alpha+, and double-negative Peyer's patch dendritic cells

1 reference

12 December 2020

Defensin deficiency, intestinal microbes, and the clinical phenotypes of Crohn's disease

1 reference

12 December 2020

Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group

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12 December 2020

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

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12 December 2020

Intestinal tolerance is converted to autoimmune enteritis upon PD-1 ligand blockade

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12 December 2020

Tolerance, DCs and tryptophan: much ado about IDO

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12 December 2020

Treatment of Crohn's disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon gamma

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12 December 2020

The B7 family revisited

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12 December 2020

The genetics and immunopathogenesis of inflammatory bowel disease

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12 December 2020

Biological therapies for inflammatory bowel diseases

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12 December 2020

Analysis of a functional BTNL2 polymorphism in type 1 diabetes, rheumatoid arthritis, and systemic lupus erythematosus.

1 reference

12 December 2020

CTLA-4 gene polymorphisms in Chinese patients with ulcerative colitis

1 reference

12 December 2020

Cytotoxic T-lymphocyte-associated antigen 4 antibody-induced colitis and its management with infliximab.

1 reference

12 December 2020

Probiotic preparation VSL#3 induces remission in children with mild to moderate acute ulcerative colitis: a pilot study.

1 reference

12 December 2020

Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division

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12 December 2020

The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression

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12 December 2020

PD-1 and its ligands in tolerance and immunity

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12 December 2020

Antibiotics should be used as first-line therapy for Crohn's disease

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12 December 2020

Control of intestinal homeostasis by regulatory T cells and dendritic cells.

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12 December 2020

New therapeutic strategies for treatment of inflammatory bowel disease

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12 December 2020

Interleukin-12 and interleukin-18 induce indoleamine 2,3-dioxygenase (IDO) activity in human osteosarcoma cell lines independently from interferon-gamma

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12 December 2020

Immunophysiology of experimental food allergy

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12 December 2020

B70 antigen is a second ligand for CTLA-4 and CD28.

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12 December 2020

Effects of Lactobacillus salivarius 433118 on intestinal inflammation, immunity status and in vitro colon function in two mouse models of inflammatory bowel disease

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12 December 2020

CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells

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12 December 2020

Celiac disease: from oral tolerance to intestinal inflammation, autoimmunity and lymphomagenesis.

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12 December 2020

NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2.

1 reference

12 December 2020

The CTLA4+49A/G and CT60 polymorphisms and chronic inflammatory arthropathies in Northern Ireland

1 reference

12 December 2020

Inflammatory bowel disease: lessons from the IL-10 gene-deficient mouse

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12 December 2020

Genetic association of type 1 diabetes in an Azerbaijanian population: the HLA-DQ, -DRB1*04, the insulin gene, and CTLA4

1 reference

12 December 2020

Isolated cardiac sarcoidosis associated with the expression of a splice variant coding for a truncated BTNL2 protein

1 reference

12 December 2020

Two major histocompatibility complex haplotypes influence susceptibility to sporadic inclusion body myositis: critical evaluation of an association with HLA-DR3.

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12 December 2020

Role of serotonin in intestinal inflammation: knockout of serotonin reuptake transporter exacerbates 2,4,6-trinitrobenzene sulfonic acid colitis in mice

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12 December 2020

Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10

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12 December 2020

Modulation of invariant natural killer T cell cytokine responses by indoleamine 2,3-dioxygenase

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12 December 2020

In vivo effects of recombinant human interleukin-10 on lymphocyte phenotypes and leukocyte activation markers in inflammatory bowel disease

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12 December 2020

The BTNL2 gene and sarcoidosis susceptibility in African Americans and Whites

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12 December 2020

Immunoreceptor tyrosine-based inhibitory motifs on activating molecules.

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12 December 2020

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

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12 December 2020

IL-10 gene therapy prevents TNBS-induced colitis

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12 December 2020

New cytokine delivery system using gelatin microspheres containing interleukin-10 for experimental inflammatory bowel disease

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12 December 2020

A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

1 reference

12 December 2020

Post-translational inhibition of IP-10 secretion in IEC by probiotic bacteria: impact on chronic inflammation

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12 December 2020

Modulation of human dendritic cell phenotype and function by probiotic bacteria

1 reference

12 December 2020

Inhibition of indoleamine 2,3-dioxygenase augments trinitrobenzene sulfonic acid colitis in mice

1 reference

12 December 2020

A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease

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12 December 2020

Anti-inflammatory properties of Lactobacillus gasseri expressing manganese superoxide dismutase using the interleukin 10-deficient mouse model of colitis

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12 December 2020

Regulatory lymphocytes and intestinal inflammation.

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12 December 2020

PD-1 signaling in primary T cells

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12 December 2020

B7 interactions with CD28 and CTLA-4 control tolerance or induction of mucosal inflammation in chronic experimental colitis

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12 December 2020

CTLA-4 is a second receptor for the B cell activation antigen B7

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12 December 2020

Ermap, a gene coding for a novel erythroid specific adhesion/receptor membrane protein

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12 December 2020

Oral IL-10 gene delivery in a microsphere-based formulation for local transfection and therapeutic efficacy in inflammatory bowel disease

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12 December 2020

Anti-adhesion molecule therapies in inflammatory bowel disease: touch and go.

1 reference

12 December 2020

Over-expression of interleukin 10 in mucosal T cells of patients with active ulcerative colitis

1 reference

12 December 2020

Effect of a probiotic preparation (VSL#3) on induction and maintenance of remission in children with ulcerative colitis

1 reference

12 December 2020

CD40 and CD86 upregulation with divergent CMRF44 expression on blood dendritic cells in inflammatory bowel diseases

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12 December 2020

Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses

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12 December 2020

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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12 December 2020

Association of the CTLA-4 gene with rheumatoid arthritis in Chinese Han population.

1 reference

12 December 2020

Dendritic cells in intestinal immune regulation.

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12 December 2020

Analysis of the BTNL2 truncating splice site mutation in tuberculosis, leprosy and Crohn's disease

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12 December 2020

Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts

1 reference

12 December 2020

10.1007/S00011-009-0091-X

Identifiers

DOI

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21 August 2017

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