Lymphoproliferative disorders involving T helper effector cells with defective LAT signalosomes (Q37682639)

22 August 2017

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title

Lymphoproliferative disorders involving T helper effector cells with defective LAT signalosomes (English)

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Gene Ontology release 2020-05-02

22 August 2017

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Gene Ontology ID

GO:0036398

lymphoproliferative disorders

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Romain Roncagalli

1

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Marie Malissen

object named as

Marie Malissen

6

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Bernard Malissen

object named as

Bernard Malissen

5

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Christelle Langlet

4

object named as

Christelle Langlet

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22 August 2017

Michael Mingueneau

2

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22 August 2017

Claude Grégoire

3

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22 August 2017

publication date

28 January 2010

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Seminars in Immunopathology

22 August 2017

published in

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22 August 2017

volume

32

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22 August 2017

issue

2

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22 August 2017

page(s)

117-125

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https://scigraph.springernature.com/pub.10.1007/s00281-009-0195-y

22 August 2017

exact match

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cites work

The Th2 lymphoproliferation developing in LatY136F mutant mice triggers polyclonal B cell activation and systemic autoimmunity.

1 reference

https://api.crossref.org/works/10.1007%2FS00281-009-0195-Y

Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-009-0195-Y

Suppression of CD4+ T lymphocyte effector functions by CD4+CD25+ cells in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-009-0195-Y

Early phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-009-0195-Y

The type 1 cysteinyl leukotriene receptor triggers calcium influx and chemotaxis in mouse alpha beta- and gamma delta effector T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-009-0195-Y

Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease

21 January 2018

1 reference

12 December 2020

LAT-mediated signaling in CD4+CD25+ regulatory T cell development

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12 December 2020

Homeostasis of naive and memory T cells

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12 December 2020

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

1 reference

12 December 2020

Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient mice

1 reference

12 December 2020

Single and combined deletions of the NTAL/LAB and LAT adaptors minimally affect B-cell development and function

1 reference

12 December 2020

Spontaneous B cell hyperactivity in autoimmune-prone MRL mice

1 reference

12 December 2020

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

1 reference

12 December 2020

Unravelling the association of partial T-cell immunodeficiency and immune dysregulation

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12 December 2020

Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene

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12 December 2020

Angioimmunoblastic T cell lymphoma: pathobiological insights and clinical implications

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12 December 2020

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

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12 December 2020

The single positive T cells found in CD3-zeta/eta-/- mice overtly react with self-major histocompatibility complex molecules upon restoration of normal surface density of T cell receptor-CD3 complex

1 reference

12 December 2020

Dok-1 and Dok-2 are negative regulators of T cell receptor signaling

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12 December 2020

LAT regulates gammadelta T cell homeostasis and differentiation

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12 December 2020

Induction of T helper type 2 immunity by a point mutation in the LAT adaptor

1 reference

12 December 2020

The essential role of LAT in thymocyte development during transition from the double-positive to single-positive stage

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12 December 2020

Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor

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12 December 2020

Persistence of cooperatively stabilized signaling clusters drives T-cell activation

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12 December 2020

Gads/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells

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12 December 2020

T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2

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12 December 2020

T-cell receptor-independent activation of clonal Th2 cells associated with chronic hypereosinophilia

1 reference

12 December 2020

STAT6 deletion converts the Th2 inflammatory pathology afflicting Lat(Y136F) mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells

1 reference

12 December 2020

Modeling T cell antigen discrimination based on feedback control of digital ERK responses

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12 December 2020

Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection

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12 December 2020

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

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12 December 2020

A LAT mutation that inhibits T cell development yet induces lymphoproliferation

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12 December 2020

10.1007/S00281-009-0195-Y

Identifiers

DOI

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release_bjsq4qs5ebczdcb4nbtw4wgjpu

22 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/bjsq4qs5ebczdcb4nbtw4wgjpu

24 November 2022

mapped directly with Wikidata item

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