Ultra low-dose IL-2 for GVHD prophylaxis after allogeneic hematopoietic stem cell transplantation mediates expansion of regulatory T cells without diminishing antiviral and antileukemic activity. (Q37707135)

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scientific article published on 26 February 2014

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English	Ultra low-dose IL-2 for GVHD prophylaxis after allogeneic hematopoietic stem cell transplantation mediates expansion of regulatory T cells without diminishing antiviral and antileukemic activity.	scientific article published on 26 February 2014

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8 March 2020

Ultra low-dose IL-2 for GVHD prophylaxis after allogeneic hematopoietic stem cell transplantation mediates expansion of regulatory T cells without diminishing antiviral and antileukemic activity (English)

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8 March 2020

stem cell transplantation

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9

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8 March 2020

14

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8 March 2020

Catherine M Bollard

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Catherine M Bollard

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8 March 2020

Malcolm Brenner

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Malcolm K Brenner

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8 March 2020

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Helen E Heslop

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8 March 2020

Barbara Savoldo

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Barbara Savoldo

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8 March 2020

Robert A Krance

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Robert A Krance

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8 March 2020

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George Carrum

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8 March 2020

Alana A Kennedy-Nasser

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Alana A Kennedy-Nasser

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8 March 2020

4

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Yasmin Hazrat

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8 March 2020

Jack Meng-Fen Su

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Meng-Fen Wu

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8 March 2020

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Eric Yvon

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8 March 2020

Kathryn S Leung

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Kathryn Leung

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8 March 2020

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Stephanie Ku

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8 March 2020

Paul Castillo-Caro

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8 March 2020

Hao Liu

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8 March 2020

Jos Melenhorst

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8 March 2020

A John Barrett

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8 March 2020

Aaron Foster

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8 March 2020

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26 February 2014

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8 March 2020

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11

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Clinical Cancer Research

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8 March 2020

20

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8 March 2020

8

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8 March 2020

2215-2225

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8 March 2020

Generation of tumor antigen-specific T cell lines from pediatric patients with acute lymphoblastic leukemia--implications for immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 August 2017

Low-dose interleukin-2 therapy restores regulatory T cell homeostasis in patients with chronic graft-versus-host disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 August 2017

Generation of multi-leukemia antigen-specific T cells to enhance the graft-versus-leukemia effect after allogeneic stem cell transplant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 August 2017

Interleukin-2 and regulatory T cells in graft-versus-host disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 August 2017

Alloreactivity across HLA barriers is mediated by both naïve and antigen-experienced T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 August 2017

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 August 2017

Characterizing and optimizing immune responses to leukaemia antigens after allogeneic stem cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 August 2017

Regulatory T cells and immune tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 August 2017

The impact of regulatory T cells on T-cell immunity following hematopoietic cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 August 2017

High donor FOXP3-positive regulatory T-cell (Treg) content is associated with a low risk of GVHD following HLA-matched allogeneic SCT

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 August 2017

Tolerance, not immunity, crucially depends on IL-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 August 2017

CD8 T cell memory in B cell-deficient mice

1 reference

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23 August 2017

A phase I clinical trial of recombinant interleukin 2 following high dose chemo-radiotherapy for haematological malignancy: applicability to the elimination of minimal residual disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 August 2017

Role of regulatory T cell populations in controlling graft vs host disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

6 September 2017

Clinical perspectives for regulatory T cells in transplantation tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

6 September 2017

T-cell responses directed against multiple HLA-A*0201-restricted epitopes derived from Wilms' tumor 1 protein in patients with leukemia and healthy donors: identification, quantification, and characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

14 September 2017

Graft-versus-leukemia reactions after bone marrow transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

28 September 2017

IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 June 2018

IL-2 infusion abrogates humoral immune responses in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

23 June 2018

Successful treatment of stem cell graft failure in pediatric patients using a submyeloablative regimen of campath-1H and fludarabine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

1 September 2018

Comparable outcome of alternative donor and matched sibling donor hematopoietic stem cell transplant for children with acute lymphoblastic leukemia in first or second remission using alemtuzumab in a myeloablative conditioning regimen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

1 September 2018

Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

1 September 2018

A phase I study of ultra low dose interleukin-2 and stem cell factor in patients with HIV infection or HIV and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

1 September 2018

Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

1 September 2018

Functional maturation of CD4+CD25+CTLA4+CD45RA+ T regulatory cells in human neonatal T cell responses to environmental antigens/allergens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

1 September 2018

Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

1 September 2018

Regulatory CD4+CD25+ T cells restrict memory CD8+ T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

1 September 2018

Characterization of CD4+CD25+ regulatory T cells in patients treated with high-dose interleukin-2 for metastatic melanoma or renal cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989436

2 October 2018

Graft-versus-host disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573552

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunotherapy: Can we include vaccines with stem-cell transplantation?

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573552

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoselection and clinical use of T regulatory cells in HLA-haploidentical stem cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573552

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573552

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of alemtuzumab used for in vivo and in vitro T-cell depletion in allogeneic transplantations: relevance for early adoptive immunotherapy and infectious complications

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573552

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of recombinant interleukin-2 administration on cytotoxic function following high-dose chemo-radiotherapy for hematological malignancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573552

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and immunologic effects of prolonged infusion of low-dose recombinant interleukin-2 after autologous and T-cell-depleted allogeneic bone marrow transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573552

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of low-dose interleukin-2 on disease relapse after T-cell-depleted allogeneic bone marrow transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573552

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incorporating toxicity considerations into the design of two-stage phase II clinical trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573552

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A PR1-human leukocyte antigen-A2 tetramer can be used to isolate low-frequency cytotoxic T lymphocytes from healthy donors that selectively lyse chronic myelogenous leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573552

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inferred from PubMed ID database lookup

Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573552

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inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-13-3205

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Europe PubMed Central

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8 March 2020

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8 March 2020

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Europe PubMed Central

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8 March 2020

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