Uncoupling protein UCP2: when mitochondrial activity meets immunity. (Q37708737)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20227410%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

review article

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title

Uncoupling protein UCP2: when mitochondrial activity meets immunity (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20227410%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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1

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19 January 2020

author name string

Tobias Nübel

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20227410%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

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publication date

15 March 2010

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19 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20227410%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

584

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19 January 2020

issue

8

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19 January 2020

page(s)

1437-1442

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Thermoregulation: what role for UCPs in mammals and birds?

19 January 2020

cites work

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Uncoupling proteins: a role in protection against reactive oxygen species--or not?

21 January 2018

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The 'novel' 'uncoupling' proteins UCP2 and UCP3: what do they really do? Pros and cons for suggested functions.

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Respiration under control of uncoupling proteins: Clinical perspective

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Avian UCP: the killjoy in the evolution of the mitochondrial uncoupling proteins

21 January 2018

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Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

21 January 2018

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UCP2 is a mitochondrial transporter with an unusual very short half-life

21 January 2018

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Translation control of UCP2 synthesis by the upstream open reading frame.

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Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

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Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

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Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity.

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UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals

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Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma

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The emerging functions of UCP2 in health, disease, and therapeutics

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Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3.

21 January 2018

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Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production

21 January 2018

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Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages

21 January 2018

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Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages

21 January 2018

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Overexpression of uncoupling protein 2 in THP1 monocytes inhibits beta2 integrin-mediated firm adhesion and transendothelial migration

21 January 2018

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Redox signaling in macrophages

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Reactive species-mediated regulation of cell signaling and the cell cycle: the role of MAPK.

21 January 2018

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Characterization of the differential expression of uncoupling protein 2 and ROS production in differentiated mouse macrophage-cells (Mm1) and the progenitor cells (M1).

21 January 2018

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Stanniocalcin-1 suppresses superoxide generation in macrophages through induction of mitochondrial UCP2

21 January 2018

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Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2.

21 January 2018

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Mitochondrial uncoupling protein 2 inhibits mast cell activation and reduces histamine content

21 January 2018

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N-acetylcysteine protects mice from lethal endotoxemia by regulating the redox state of immune cells.

21 January 2018

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Reactive oxygen and nitrogen species differentially regulate Toll-like receptor 4-mediated activation of NF-kappa B and interleukin-8 expression

21 January 2018

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Protective role of uncoupling protein 2 in atherosclerosis

21 January 2018

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Uncoupling protein 2 has protective function during experimental autoimmune encephalomyelitis.

21 January 2018

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Role of uncoupling protein UCP2 in cell-mediated immunity: how macrophage-mediated insulitis is accelerated in a model of autoimmune diabetes.

21 January 2018

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Associations of the UCP2 gene locus with asymptomatic carotid atherosclerosis in middle-aged women.

21 January 2018

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Association of UCP2 -866 G/A polymorphism with chronic inflammatory diseases

21 January 2018

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Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels

21 January 2018

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Reduced antioxidant capacity and diet-induced atherosclerosis in uncoupling protein-2-deficient mice

21 January 2018

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Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function

21 January 2018

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Uncoupling: new approaches to an old problem of bioenergetics

21 January 2018

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The mitochondrial uncoupling-protein homologues

21 January 2018

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No evidence for a basal, retinoic, or superoxide-induced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria.

21 January 2018

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Modified glutamine catabolism in macrophages of Ucp2 knock-out mice

21 January 2018

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Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization.

21 January 2018

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Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species.

21 January 2018

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UCP2, UCP3, avUCP, what do they do when proton transport is not stimulated? Possible relevance to pyruvate and glutamine metabolism.

21 January 2018

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UCP2, a metabolic sensor coupling glucose oxidation to mitochondrial metabolism?

21 January 2018

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UCP2, not a physiologically relevant uncoupler but a glucose sparing switch impacting ROS production and glucose sensing

21 January 2018

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Glutamine stimulates translation of uncoupling protein 2mRNA.

21 January 2018

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Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Analysis of the Gene Expression Profiles of Immature versus Mature Bone Marrow-Derived Dendritic Cells Using DNA Arrays

21 January 2018

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10.1016/J.FEBSLET.2010.03.014

21 January 2018

Identifiers

DOI

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release_xkhvladk2fdh3jexh6urm3pt2e

19 January 2020

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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