TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth. (Q37713832)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28352660%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

title

TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28352660%20AND%20SRC:MED&resulttype=core&format=json

pneumococcal conjugate vaccine

14 March 2020

main subject

toll-like receptor

0 references

1 reference

1 reference

2

1 reference

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14 March 2020

author name string

David J Dowling

1

1 reference

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14 March 2020

Annette Scheid

3

1 reference

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14 March 2020

Ilana Bergelson

4

1 reference

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14 March 2020

Dhohyung Kim

5

1 reference

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14 March 2020

Christy J Mancuso

6

1 reference

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14 March 2020

Willemina Foppen

7

1 reference

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14 March 2020

Al Ozonoff

8

1 reference

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14 March 2020

Lynn Fresh

9

1 reference

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14 March 2020

Terese B Theriot

10

1 reference

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14 March 2020

Andrew A Lackner

11

1 reference

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14 March 2020

Raina N Fichorova

12

1 reference

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14 March 2020

Dmitri Smirnov

13

1 reference

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14 March 2020

John P Vasilakos

14

1 reference

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14 March 2020

Joe M Beaurline

15

1 reference

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14 March 2020

Mark A Tomai

16

1 reference

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14 March 2020

Cecily C Midkiff

17

1 reference

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14 March 2020

Xavier Alvarez

18

1 reference

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14 March 2020

James L Blanchard

19

1 reference

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14 March 2020

Margaret H Gilbert

20

1 reference

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14 March 2020

Pyone Pyone Aye

21

1 reference

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14 March 2020

Ofer Levy

22

1 reference

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14 March 2020

publication date

23 March 2017

1 reference

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14 March 2020

1 reference

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14 March 2020

volume

2

1 reference

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14 March 2020

issue

6

1 reference

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14 March 2020

page(s)

e91020

1 reference

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Pediatric Vaccine Adjuvants: Components of the Modern Vaccinologist's Toolbox

14 March 2020

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23 August 2017

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23 August 2017

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A chimeric alphavirus replicon particle vaccine expressing the hemagglutinin and fusion proteins protects juvenile and infant rhesus macaques from measles

23 August 2017

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Neonatal pneumococcal conjugate vaccine immunization primes T cells for preferential Th2 cytokine expression: a randomized controlled trial in Papua New Guinea

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Nasopharyngeal carriage of Streptococcus pneumoniae shortly before vaccination with a pneumococcal conjugate vaccine causes serotype-specific hyporesponsiveness in early infancy

6 September 2017

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A Novel R848-Conjugated Inactivated Influenza Virus Vaccine Is Efficacious and Safe in a Neonate Nonhuman Primate Model

6 September 2017

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Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization.

14 September 2017

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Distinct TLR-mediated cytokine production and immunoglobulin secretion in human newborn naïve B cells

14 September 2017

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Neonatal immunization with a Sindbis virus-DNA measles vaccine induces adult-like neutralizing antibodies and cell-mediated immunity in the presence of maternal antibodies

14 September 2017

1 reference

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The effect of stable macromolecular complexes of ionic polyphosphazene on HIV Gag antigen and on activation of human dendritic cells and presentation to T-cells

14 September 2017

1 reference

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Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways

23 June 2018

1 reference

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Development and validation of a fourfold multiplexed opsonization assay (MOPA4) for pneumococcal antibodies

23 June 2018

1 reference

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Selective impairment of TLR-mediated innate immunity in human newborns: neonatal blood plasma reduces monocyte TNF-alpha induction by bacterial lipopeptides, lipopolysaccharide, and imiquimod, but preserves the response to R-848.

23 June 2018

1 reference

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Antibody avidity determination by ELISA using thiocyanate elution.

23 June 2018

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Predictive markers of safety and immunogenicity of adjuvanted vaccines

23 June 2018

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Environmental and T cell-intrinsic factors limit the expansion of neonatal follicular T helper cells but may be circumvented by specific adjuvants

1 September 2018

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Effect of early carriage of Streptococcus pneumoniae on the development of pneumococcal protein-specific cellular immune responses in infancy.

1 September 2018

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Vaccines for the twenty-first century society.

1 September 2018

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1 September 2018

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A single immunization near birth elicits immediate and lifelong protective immunity.

1 September 2018

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Maintaining protection against invasive bacteria with protein-polysaccharide conjugate vaccines.

1 September 2018

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Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses.

1 September 2018

1 reference

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Genetic analysis of Toll/Interleukin-1 Receptor (TIR) domain sequences from rhesus macaque Toll-like receptors (TLRs) 1-10 reveals high homology to human TLR/TIR sequences

1 September 2018

1 reference

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Neonatal adaptive immunity comes of age

1 September 2018

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12 December 2020

Immunogenicity and Safety of 13-Valent Pneumococcal Conjugate Vaccine in Infants and Toddlers

1 reference

12 December 2020

Correlations between methods for measurement of synergy

1 reference

12 December 2020

Phase 3 trial evaluating the immunogenicity, safety, and tolerability of manufacturing scale 13-valent pneumococcal conjugate vaccine

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12 December 2020

Vaccine adjuvant activity of 3M-052: an imidazoquinoline designed for local activity without systemic cytokine induction

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12 December 2020

10.1172/JCI.INSIGHT.91020

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28352660%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28352660%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

PubMed publication ID

28352660

1 reference