Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response. (Q37713902)

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scientific article published on 29 January 2014

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English	Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response.	scientific article published on 29 January 2014

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scholarly article

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6 March 2020

Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response (English)

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6 March 2020

Chikungunya virus

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Martijn J van Hemert

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Florine Scholte

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Irina C Albulescu

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Irina C Albulescu

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Cindy Chiang

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Carmen Nichols

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Zhong He

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Rongtuan Lin

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John Hiscott

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29 January 2014

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Journal of Virology

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4180-4194

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Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates

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ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon

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Viperin restricts chikungunya virus replication and pathology

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Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

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Activation of Toll-like receptor 3 impairs the dengue virus serotype 2 replication through induction of IFN-β in cultured hepatoma cells

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A diverse range of gene products are effectors of the type I interferon antiviral response

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RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection

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Pathogen recognition by the innate immune system

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Inhibition of the type I interferon response in human dendritic cells by dengue virus infection requires a catalytically active NS2B3 complex

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Type I IFN controls chikungunya virus via its action on nonhematopoietic cells

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SnapShot: Pattern-recognition receptors

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12 December 2020

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10.1128/JVI.03114-13

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6 March 2020

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6 March 2020

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6 March 2020

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