The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome (Q37724585)

22 August 2017

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title

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome (English)

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22 August 2017

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5

Robert H Lustig

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22 August 2017

Jung Sub Lim

1

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22 August 2017

Michele Mietus-Snyder

series ordinal

2

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22 August 2017

Annie Valente

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3

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22 August 2017

Jean-Marc Schwarz

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4

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22 August 2017

language of work or name

English

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publication date

6 April 2010

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Nature Reviews Gastroenterology & Hepatology

22 August 2017

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22 August 2017

7

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22 August 2017

251-264

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22 August 2017

5

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https://scigraph.springernature.com/pub.10.1038/nrgastro.2010.41

22 August 2017

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31 March 2020

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Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

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Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women

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Differential effects of central fructose and glucose on hypothalamic malonyl-CoA and food intake.

31 March 2020

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Triglycerides induce leptin resistance at the blood-brain barrier

31 March 2020

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Childhood obesity: behavioral aberration or biochemical drive? Reinterpreting the First Law of Thermodynamics

31 March 2020

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High prevalence of small intestinal bacterial overgrowth in patients with morbid obesity: a contributor to severe hepatic steatosis.

31 March 2020

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31 March 2020

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Effect of fructose overfeeding and fish oil administration on hepatic de novo lipogenesis and insulin sensitivity in healthy men.

31 March 2020

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Regulation of ether lipids and their precursors in relation to glycolysis in cultured neoplastic cells

31 March 2020

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Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

31 March 2020

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The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance.

31 March 2020

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De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption

31 March 2020

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Molecular mechanisms of alcoholic fatty liver: role of sterol regulatory element-binding proteins

31 March 2020

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Amelioration of high fructose-induced metabolic derangements by activation of PPARalpha

31 March 2020

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Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance

31 March 2020

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Alterations in the regulatory properties of hepatic fatty acid oxidation and carnitine palmitoyltransferase I activity after ethanol feeding and withdrawal

31 March 2020

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Acetaldehyde-induced mitochondrial dysfunction sensitizes hepatocytes to oxidative damage

31 March 2020

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Ethanol consumption impairs regulation of fatty acid metabolism by decreasing the activity of AMP-activated protein kinase in rat liver.

31 March 2020

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Activation of peroxisome proliferator-activated receptor alpha increases the expression and activity of microsomal triglyceride transfer protein in the liver

31 March 2020

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Impairment of hepatic Stat-3 activation and reduction of PPARalpha activity in fructose-fed rats

31 March 2020

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Alcoholic liver injury in the rat is associated with reduced expression of peroxisome proliferator-alpha (PPARalpha)-regulated genes and is ameliorated by PPARalpha activation

31 March 2020

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Dietary fructose induces a wide range of genes with distinct shift in carbohydrate and lipid metabolism in fed and fasted rat liver

31 March 2020

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Polymorphism in microsomal triglyceride transfer protein: a link between liver disease and atherogenic postprandial lipid profile in NASH?

31 March 2020

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Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance

31 March 2020

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Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production

31 March 2020

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Alcohol and lipid metabolism

31 March 2020

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Alcohol and atherosclerosis

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Hyperinsulinemia is associated with increased production rate of intestinal apolipoprotein B-48-containing lipoproteins in humans.

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Consuming fructose-sweetened beverages increases body adiposity in mice.

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Fructose-induced fatty liver disease: hepatic effects of blood pressure and plasma triglyceride reduction

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Polymorphisms in the peroxisome proliferator activated receptor alpha gene are associated with levels of apolipoprotein CIII and triglyceride in African-Americans but not Caucasians

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Diagnosis of nonalcoholic fatty liver disease: invasive versus noninvasive

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Non-alcoholic fatty liver disease in obese children evaluated by magnetic resonance imaging.

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Protein fructosylation: fructose and the Maillard reaction

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Fructose-mediated non-enzymatic glycation: sweet coupling or bad modification

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Hydroxyl radical mediates N epsilon-(carboxymethyl)lysine formation from Amadori product

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Reaction of monosaccharides with proteins: possible evolutionary significance

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Fructose-induced structural and functional modifications of hemoglobin: implication for oxidative stress in diabetes mellitus.

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Dietary choline: biochemistry, physiology, and pharmacology

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Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis

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Impact of micronutrient deficiencies on obesity

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Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors

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The role of fatty acids in the development and progression of nonalcoholic fatty liver disease

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Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase

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Endoplasmic reticulum stress and the unfolded protein response

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The epidemiology of nonalcoholic fatty liver disease: a global perspective

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Identifiers

DOI

10.1038/NRGASTRO.2010.41

1 reference

Dimensions Publication ID

22 August 2017

0 references

1 reference