Soluble epoxide hydrolase inhibitors: a patent review (Q37739429)

22 August 2017

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title

Soluble epoxide hydrolase inhibitors: a patent review (English)

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Soluble epoxide hydrolase

22 August 2017

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author name string

Hong C Shen

series ordinal

1

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PubMed ID

20429668

22 August 2017

language of work or name

English

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publication date

1 July 2010

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Expert Opinion on Therapeutic Patents

22 August 2017

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22 August 2017

20

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22 August 2017

941-956

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22 August 2017

7

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Epoxide hydrolases: their roles and interactions with lipid metabolism

22 August 2017

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https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Epoxide hydrolases: biochemistry and molecular biology

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Emerging role of epoxyeicosatrienoic acids in coronary vascular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Cytochrome P450 2C is an EDHF synthase in coronary arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Cytochrome P450 metabolites of arachidonic acid in the control of renal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

P-450 metabolites of arachidonic acid in the control of cardiovascular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Effects of selective inhibition of cytochrome P-450 omega-hydroxylases and ischemic preconditioning in myocardial protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Mechanisms by which epoxyeicosatrienoic acids (EETs) elicit cardioprotection in rat hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Human soluble epoxide hydrolase: structural basis of inhibition by 4-(3-cyclohexylureido)-carboxylic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Design, synthesis, and biological activity of 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Peptidyl-urea based inhibitors of soluble epoxide hydrolases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

The 5-substituted piperazine as a novel secondary pharmacophore greatly improving the physical properties of urea-based inhibitors of soluble epoxide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Inhibition of epoxide hydrolases and glutathione S-transferases by 2-, 3-, and 4-substituted derivatives of 4'-phenylchalcone and its oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Potent urea and carbamate inhibitors of soluble epoxide hydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

A strategy of employing aminoheterocycles as amide mimics to identify novel, potent and bioavailable soluble epoxide hydrolase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Orally bioavailable potent soluble epoxide hydrolase inhibitors

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2010.484804

Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.484804

10.1517/13543776.2010.484804

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference

PubMed ID

20429668