New pharmacological treatments for improving renal outcomes in diabetes (Q37741787)

22 August 2017

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title

New pharmacological treatments for improving renal outcomes in diabetes (English)

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22 August 2017

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Anne-Emilie Declèves

1

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PubMed ID

20440278

22 August 2017

Kumar Sharma

series ordinal

2

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PubMed ID

20440278

22 August 2017

language of work or name

English

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publication date

4 May 2010

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Nature Reviews Nephrology

22 August 2017

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22 August 2017

6

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22 August 2017

6

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22 August 2017

371-380

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https://scigraph.springernature.com/pub.10.1038/nrneph.2010.57

22 August 2017

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HMG-CoA reductase inhibitor ameliorates diabetic nephropathy by its pleiotropic effects in rats

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Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator

31 March 2020

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Novel aspects of transforming growth factor-Beta in diabetic kidney disease

31 March 2020

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TGF-beta in diabetic kidney disease: role of novel signaling pathways

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Epithelial-mesenchymal transition as a potential explanation for podocyte depletion in diabetic nephropathy.

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Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice

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Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice

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Reversibility of established diabetic glomerulopathy by anti-TGF-beta antibodies in db/db mice.

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Soluble betaglycan reduces renal damage progression in db/db mice.

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Delivery of plasmid DNA expressing small interference RNA for TGF-beta type II receptor by cationized gelatin to prevent interstitial renal fibrosis

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Add-on angiotensin II receptor blockade lowers urinary transforming growth factor-beta levels

31 March 2020

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Captopril-induced reduction of serum levels of transforming growth factor-beta1 correlates with long-term renoprotection in insulin-dependent diabetic patients

31 March 2020

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Add-on anti-TGF-beta antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat.

31 March 2020

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Angiotensin-converting enzyme inhibition but not beta-adrenergic blockade limits transforming growth factor-beta overexpression in acute normotensive anti-thy1 glomerulonephritis

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Simvastatin attenuates renal inflammation, tubular transdifferentiation and interstitial fibrosis in rats with unilateral ureteral obstruction

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Simvastatin abates development of renal fibrosis in experimental renovascular disease

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The treatment of liver fibrosis induced by hepatocyte growth factor-directed, ultrasound-targeted microbubble destruction in rats

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Systemic administration of naked plasmid encoding hepatocyte growth factor ameliorates chronic renal fibrosis in mice

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Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy

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Hepatocyte growth factor prevents renal fibrosis and dysfunction in a mouse model of chronic renal disease

31 March 2020

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Hepatocyte growth factor gene therapy and angiotensin II blockade synergistically attenuate renal interstitial fibrosis in mice

31 March 2020

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Plasma connective tissue growth factor is an independent predictor of end-stage renal disease and mortality in type 1 diabetic nephropathy

31 March 2020

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Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes

31 March 2020

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Inhibition of connective tissue growth factor by small interfering RNA prevents renal fibrosis in rats undergoing chronic allograft nephropathy

31 March 2020

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Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats

31 March 2020

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Pirfenidone improves renal function and fibrosis in the post-obstructed kidney

31 March 2020

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Pirfenidone inhibits NADPH-dependent microsomal lipid peroxidation and scavenges hydroxyl radicals

31 March 2020

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Pirfenidone Slows Renal Function Decline in Patients with Focal Segmental Glomerulosclerosis

31 March 2020

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Double-blind, placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis

31 March 2020

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Pirfenidone is renoprotective in diabetic kidney disease

31 March 2020

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Fluorofenidone attenuates collagen I and transforming growth factor-beta1 expression through a nicotinamide adenine dinucleotide phosphate oxidase-dependent way in NRK-52E cells

31 March 2020

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Albuminuria is directly associated with increased plasma PAI-1 and factor VII levels in NIDDM patients

31 March 2020

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Plasminogen activator inhibitor-1 deficiency retards diabetic nephropathy

31 March 2020

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A PAI-1 mutant, PAI-1R, slows progression of diabetic nephropathy

31 March 2020

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PAI-1 and kidney fibrosis

31 March 2020

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Positive feedback loop between plasminogen activator inhibitor-1 and transforming growth factor-beta1 during renal fibrosis in diabetes

31 March 2020

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Rhein reverses the diabetic phenotype of mesangial cells over-expressing the glucose transporter (GLUT1) by inhibiting the hexosamine pathway

31 March 2020

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Rhein improves renal lesion and ameliorates dyslipidemia in db/db mice with diabetic nephropathy

31 March 2020

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AGEs induce oxidative stress and activate protein kinase C-beta(II) in neonatal mesangial cells

31 March 2020

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Differential expression of protein kinase C isoforms in streptozotocin-induced diabetic rats

31 March 2020

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Protein kinase C activation and the development of diabetic complications

31 March 2020

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Protein kinase C beta inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension

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The effect of ruboxistaurin on nephropathy in type 2 diabetes

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Human prorenin: pathophysiology and clinical implications

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Connective tissue growth factor (CTGF): a key factor in the onset and progression of kidney damage

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Oxidative modification of low-density lipoprotein enhances the murine mesangial cell cytokines associated with monocyte migration, differentiation, and proliferation.

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12 December 2020

Effect of duration of type I diabetes on the prevalence of stages of diabetic nephropathy defined by urinary albumin/creatinine ratio.

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Induction of glomerulosclerosis by dietary lipids. A functional and morphologic study in the rat

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Potential role of TGF-beta in diabetic nephropathy

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Lovastatin inhibits transforming growth factor-beta1 expression in diabetic rat glomeruli and cultured rat mesangial cells

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12 December 2020

Hepatocyte growth factor: renotropic role and potential therapeutics for renal diseases

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12 December 2020

Epithelial to mesenchymal transition in the progression of tubulointerstitial fibrosis.

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12 December 2020

Pirfenidone prevents collagen accumulation in the remnant kidney in rats with partial nephrectomy

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12 December 2020

Identifiers

DOI

10.1038/NRNEPH.2010.57

1 reference

22 August 2017

1 reference

PubMed ID

20440278