Mouse models of systemic lupus erythematosus reveal a complex pathogenesis (Q37744348)

22 August 2017

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title

Mouse models of systemic lupus erythematosus reveal a complex pathogenesis (English)

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systemic lupus erythematosus

22 August 2017

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author name string

J B Rottman

series ordinal

1

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PubMed ID

20448279

22 August 2017

C R Willis

series ordinal

2

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22 August 2017

6 May 2010

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22 August 2017

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22 August 2017

47

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22 August 2017

4

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22 August 2017

664-676

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Safety and efficacy of tumor necrosis factor alpha blockade in systemic lupus erythematosus: an open-label study

22 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Dose-dependent induction of anti-native DNA antibodies in cats by propylthiouracil

21 January 2018

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https://api.crossref.org/works/10.1177%2F0300985810370005

Profiles of gene expression in human autoimmune disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Positive and negative effects of thalidomide on refractory cutaneous lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

B cells move to centre stage: novel opportunities for autoimmune disease treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Human regulatory T cells: role in autoimmune disease and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Regulation of lupus-related autoantibody production and clinical disease by Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Accelerated macrophage apoptosis induces autoantibody formation and organ damage in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Epitope spreading within lupus-associated ribonucleoprotein antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

CXCR3+CD4+ T cells are enriched in inflamed kidneys and urine and provide a new biomarker for acute nephritis flares in systemic lupus erythematosus patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Systemic lupus erythematosus: multiple immunological phenotypes in a complex genetic disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Treatment of murine lupus with CTLA4Ig

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

T cells and B cells in lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Veterinary autoimmunity: autoimmune diseases in domestic animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Cellular and genetic mechanisms of self tolerance and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Canine discoid lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

BAFF and MyD88 signals promote a lupuslike disease independent of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Deposition of nucleosomal antigens (histones and DNA) in the epidermal basement membrane in human lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

The curiously suspicious: a role for Epstein-Barr virus in lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Epstein-Barr virus infection may be an environmental risk factor for systemic lupus erythematosus in children and teenagers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Dissection of BXSB Lupus Phenotype Using Mice Congenic for Chromosome 1 Demonstrates That Separate Intervals Direct Different Aspects of Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Cutting edge: Regulatory T cells directly suppress B cells in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Toll-like receptor control of the adaptive immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Canine systemic lupus erythematosus: new insights and their implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Demethylation of promoter regulatory elements contributes to perforin overexpression in CD4+ lupus T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Murine lupus in MRL/lpr mice lacking CD4 or CD8 T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Up-regulated expression of Toll-like receptors mRNAs in peripheral blood mononuclear cells from patients with systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

CD4(+)CD25 (+) regulatory T cells in human lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Newer drugs for the treatment of lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Manipulation of immune regulation in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Toll-like receptors and innate immune responses in systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Genetics of lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

DNA methylation and chromatin structure regulate T cell perforin gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

BAFF AND APRIL: a tutorial on B cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Complete heart block associated with lupus in a dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Lupus nephritis: the central role of nucleosomes revealed

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Epigenetics: interaction of DNA methylation and chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Features of systemic lupus erythematosus in Dnase1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Innate immune collectin surfactant protein D enhances the clearance of DNA by macrophages and minimizes anti-DNA antibody generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Epigenetic regulation and the pathogenesis of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

The genetics of SLE: an update in the light of genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Primer: epigenetics of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Autoreactive B cell regulation: peripheral induction of developmental arrest by lupus-associated autoantigens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Induction of lupus-associated autoantibodies in BALB/c mice by intraperitoneal injection of pristane

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

DNA methylation: its contribution to systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Remission of proliferative lupus nephritis following B cell depletion therapy is preceded by down-regulation of the T cell costimulatory molecule CD40 ligand: an open-label trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Lenalidomide for the treatment of resistant discoid lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

From T to B and back again: positive feedback in systemic autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

The role of B cells in lpr/lpr-induced autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Lupus-type "anticoagulant" in a dog with hemolysis and thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

A Tlr7 translocation accelerates systemic autoimmunity in murine lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

TLR7/9 antagonists as therapeutics for immune-mediated inflammatory disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

The genes of systemic autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Regulatory T cells in human autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Complement deficiencies and systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Mechanism of action of combined short-term CTLA4Ig and anti-CD40 ligand in murine systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Effect of an exogenous trigger on the pathogenesis of lupus in (NZB x NZW)F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Anti-DNA antibodies in the pathogenesis of lupus nephritis--the emerging mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Identification of systemically expanded activated T cell clones in MRL/lpr and NZB/W F1 lupus model mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

BAFF costimulation of Toll-like receptor-activatedB-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985810370005

21 January 2018

Identifiers

DOI

10.1177/0300985810370005

1 reference

22 August 2017

1 reference

PubMed ID

20448279