B cells move to centre stage: novel opportunities for autoimmune disease treatment (Q34544062)

2 August 2017

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title

B cells move to centre stage: novel opportunities for autoimmune disease treatment (English)

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2 August 2017

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Jeffrey L Browning

1

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publication date

1 July 2006

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Nature Reviews Drug Discovery

2 August 2017

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2 August 2017

5

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2 August 2017

7

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2 August 2017

564-576

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https://scigraph.springernature.com/pub.10.1038/nrd2085

2 August 2017

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8.

31 March 2020

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Toll-like receptors, endogenous ligands, and systemic autoimmune disease.

31 March 2020

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Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus

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Toll-like receptor activation in the pathogenesis of systemic lupus erythematosus

31 March 2020

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31 March 2020

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Fcgamma receptors: old friends and new family members

31 March 2020

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31 March 2020

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The inhibitory Fcγ receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells

31 March 2020

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Restoration of tolerance in lupus by targeted inhibitory receptor expression

31 March 2020

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Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts

31 March 2020

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FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling.

31 March 2020

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Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus

31 March 2020

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Complement and its breakdown products in SLE.

31 March 2020

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Therapeutic intravenous immunoglobulins

31 March 2020

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Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels.

31 March 2020

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Acute glomerulonephritis occurring during immunoadsorption with staphylococcal protein A column (Prosorba).

31 March 2020

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Novel Approaches to Therapy for SLE.

31 March 2020

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Anti-immunoglobulin E treatment with omalizumab in allergic diseases: an update on anti-inflammatory activity and clinical efficacy

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31 March 2020

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31 March 2020

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Challenges in bringing the bench to bedside in drug development for SLE.

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31 March 2020

Identifiers

DOI

10.1038/NRD2085

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2 August 2017

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PubMed ID

16816838