Cell penetrating elastin-like polypeptides for therapeutic peptide delivery (Q37755594)

22 August 2017

1 reference

title

Cell penetrating elastin-like polypeptides for therapeutic peptide delivery (English)

1 reference

22 August 2017

Gene L Bidwell

1

1 reference

PMCID

2964383

22 August 2017

Drazen Raucher

series ordinal

2

1 reference

PMCID

2964383

22 August 2017

language of work or name

English

0 references

publication date

15 May 2010

1 reference

Advanced Drug Delivery Reviews

22 August 2017

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22 August 2017

62

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22 August 2017

15

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22 August 2017

1486-1496

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Micelles based on HPMA copolymers

22 August 2017

1 reference

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Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumours after a single injection

22 August 2017

1 reference

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Therapeutic peptides for cancer therapy. Part II - cell cycle inhibitory peptides and apoptosis-inducing peptides

22 August 2017

1 reference

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Bioconjugates: harnessing potential for effective therapeutics

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1 reference

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Biodegradable amphiphilic polymer-drug conjugate micelles

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Therapeutic peptides for cancer therapy. Part I - peptide inhibitors of signal transduction cascades.

22 August 2017

1 reference

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Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier

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1 reference

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Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics

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1 reference

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Protein transduction revisited: novel insights into the mechanism underlying intracellular delivery of proteins

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1 reference

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Synthesis and characterization of a thermally-responsive tumor necrosis factor antagonist

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1 reference

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Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines.

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Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors

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Applications of a blood-brain barrier technology platform to predict CNS penetration of various chemotherapeutic agents. 2. Cationic peptide vectors for brain delivery

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1 reference

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Exploiting the enhanced permeability and retention effect for tumor targeting

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1 reference

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Polymer conjugates: nanosized medicines for treating cancer

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1 reference

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Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides

22 August 2017

1 reference

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Intracellular targeting of polymer-bound drugs for cancer chemotherapy

22 August 2017

1 reference

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The use of cell-penetrating peptides for drug delivery

22 August 2017

1 reference

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Cell penetrating peptides in drug delivery

22 August 2017

1 reference

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TAT-liposomes: a novel intracellular drug carrier

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1 reference

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TAT peptide internalization: seeking the mechanism of entry.

22 August 2017

1 reference

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Peptide delivery to the brain via adsorptive-mediated endocytosis: advances with SynB vectors

22 August 2017

1 reference

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c-MYC: more than just a matter of life and death

22 August 2017

1 reference

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Genetically encoded synthesis of protein-based polymers with precisely specified molecular weight and sequence by recursive directional ligation: examples from the elastin-like polypeptide system.

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Clinical application of hyperthermia combined with anticancer drugs for the treatment of solid tumors

22 August 2017

1 reference

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Transport of molecules, particles, and cells in solid tumors

22 August 2017

1 reference

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Transmembrane transport of peptide type compounds: prospects for oral delivery

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

22 August 2017

Hyperthermia in oncology

1 reference

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Biodegradable nanoparticles for oral delivery of peptides: is there a role for polymers to affect mucosal uptake?

22 August 2017

1 reference

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New advances in the transport of doxorubicin through the blood-brain barrier by a peptide vector-mediated strategy.

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

In vivo protein transduction: delivery of a biologically active protein into the mouse

22 August 2017

1 reference

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Treatment with inhibitors of polyamine biosynthesis, which selectively lower intracellular spermine, does not affect the activity of alkylating agents but antagonizes the cytotoxicity of DNA topoisomerase II inhibitors.

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

The third helix of the Antennapedia homeodomain translocates through biological membranes.

22 August 2017

1 reference

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Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence

22 August 2017

1 reference

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A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Spermine-DNA interactions: a theoretical study

22 August 2017

1 reference

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Transport of molecules across tumor vasculature

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Free energy transduction in polypeptides and proteins based on inverse temperature transitions

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Delivery of novel therapeutic agents in tumors: physiological barriers and strategies

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Application of thermally responsive elastin-like polypeptide fused to a lactoferrin-derived peptide for treatment of pancreatic cancer.

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Targeting a c-Myc inhibitory polypeptide to specific intracellular compartments using cell penetrating peptides.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

A thermally targeted elastin-like polypeptide-doxorubicin conjugate overcomes drug resistance.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Development of elastin-like polypeptide for thermally targeted delivery of doxorubicin.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Tumor accumulation, degradation and pharmacokinetics of elastin-like polypeptides in nude mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Enhancing the antiproliferative effect of topoisomerase II inhibitors using a polypeptide inhibitor of c-Myc

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Application of thermally responsive polypeptides directed against c-Myc transcriptional function for cancer therapy.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Translocating proline-rich peptides from the antimicrobial peptide bactenecin 7.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Regional hyperthermia combined with systemic chemotherapy of locally advanced sarcomas: preclinical aspects and clinical results.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

A retro-inverso peptide homologous to helix 1 of c-Myc is a potent and specific inhibitor of proliferation in different cellular systems

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Hyperthermic treatment of malignant diseases: current status and a view toward the future.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Characterization of p21Cip1/Waf1 peptide domains required for cyclin E/Cdk2 and PCNA interaction.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Effect of polyamine depletion by alpha-difluoromethylornithine or (2R,5R)-6-heptyne-2,5-diamine on drug-induced topoisomerase II-mediated DNA cleavage and cytotoxicity in human and murine leukemia cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Evaluation of an elastin-like polypeptide-doxorubicin conjugate for cancer therapy.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Caveolae and cholesterol distribution in vascular smooth muscle cells of different phenotypes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Trojan peptides: the penetratin system for intracellular delivery

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Rationale and clinical status of local hyperthermia, radiation, and chemotherapy in locally advanced malignancies.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Interaction of the bHLH-zip domain of c-Myc with H1-type peptides. Characterization of helicity in the H1 peptides by NMR.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

Depletion of intracellular polyamines may alter DNA conformation in 9L rat brain tumor cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964383

A p21(Waf1/Cip1)carboxyl-terminal peptide exhibited cyclin-dependent kinase-inhibitory activity and cytotoxicity when introduced into human cells

1 September 2018

1 reference

12 December 2020

Inhibition of cancer cell growth and c-Myc transcriptional activity by a c-Myc helix 1-type peptide fused to an internalization sequence

1 reference

12 December 2020

p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells

1 reference

12 December 2020

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1 reference

12 December 2020

Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1

1 reference

12 December 2020

Inhibition of nucleotide excision repair by the cyclin-dependent kinase inhibitor p21

1 reference

12 December 2020

Phase-structure transitions of the elastin polypentapeptide-water system within the framework of composition-temperature studies

1 reference

12 December 2020

Pharmacodynamic aspects of peptide administration biological response modifiers

1 reference

12 December 2020

Inhibition of cell proliferation by the PCNA-binding region of p21 expressed as a GFP miniprotein

1 reference

12 December 2020

Prostate perfusion in patients with locally advanced prostate carcinoma treated with different hyperthermia techniques

1 reference

12 December 2020

10.1016/J.ADDR.2010.05.003

Identifiers

DOI

1 reference

22 August 2017

1 reference

22 August 2017

1 reference

PMCID

2964383