Pharmacological issues of linezolid: an updated critical review (Q37763074)

22 August 2017

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title

Pharmacological issues of linezolid: an updated critical review (English)

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22 August 2017

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4

Romano Danesi

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22 August 2017

Antonello Di Paolo

1

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22 August 2017

Paolo Malacarne

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2

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22 August 2017

Emanuele Guidotti

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3

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22 August 2017

Mario Del Tacca

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5

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22 August 2017

1 July 2010

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Clinical Pharmacokinetics

22 August 2017

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22 August 2017

49

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22 August 2017

7

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22 August 2017

439-447

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https://scigraph.springernature.com/pub.10.2165/11319960-000000000-00000

22 August 2017

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Linezolid clearance during continuous venovenous hemodiafiltration: a case report

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Antimicrobial therapy in critically ill patients: a review of pathophysiological conditions responsible for altered disposition and pharmacokinetic variability

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Pharmacokinetics, metabolism, and excretion of linezolid following an oral dose of [(14)C]linezolid to healthy human subjects.

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Nosocomial spread of linezolid-resistant, vancomycin-resistant Enterococcus faecium

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Pharmacokinetics and pharmacodynamics of linezolid in obese patients with cellulitis

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Association of pharmacokinetic and pharmacodynamic aspects of linezolid with infection outcome

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Successful treatment of vancomycin-resistant Enterococcus faecium endocarditis with linezolid in a renal transplant recipient with human immunodeficiency virus infection

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Clearance of linezolid via continuous venovenous hemodiafiltration

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Drug metabolism and disposition in children

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Linezolid-associated serotonin syndrome after concomitant treatment with citalopram and mirtazepine in a critically ill bone marrow transplant recipient

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Antimicrobial resistance in Europe and its potential impact on empirical therapy.

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Efficacy and pharmacodynamics of linezolid, alone and in combination with rifampicin, in an experimental model of methicillin-resistant Staphylococcus aureus endocarditis

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Myelosuppression and serotonin syndrome associated with concurrent use of linezolid and selective serotonin reuptake inhibitors in bone marrow transplant recipients

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Linezolid versus glycopeptide or beta-lactam for treatment of Gram-positive bacterial infections: meta-analysis of randomised controlled trials

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12 December 2020

Methicillin-resistant Staphylococcus aureus infection in a renal allograft recipient treated successfully with a novel new antimicrobial agent (linezolid): new treatment options for infections due to resistant organisms.

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Linezolid-induced inhibition of mitochondrial protein synthesis.

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Influence of burns on pharmacokinetics and pharmacodynamics of drugs used in the care of burn patients

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12 December 2020

Linezolid and vancomycin, alone and in combination with rifampin, compared with moxifloxacin against a multidrug-resistant and a vancomycin-tolerant Streptococcus pneumoniae strain in an in vitro pharmacodynamic model

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12 December 2020

Pharmacokinetics of intravenous linezolid in cerebrospinal fluid and plasma in neurointensive care patients with staphylococcal ventriculitis associated with external ventricular drains

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12 December 2020

Serotonin syndrome precipitated by linezolid in a medically ill patient on duloxetine

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12 December 2020

Pharmacokinetics of repeated dosing of linezolid in a hemodialysis patient with chronic renal failure

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12 December 2020

Multiple-dose pharmacokinetics of linezolid during continuous venovenous haemofiltration

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12 December 2020

Hyperlactacidemia potentially due to linezolid overexposure in a liver transplant recipient

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12 December 2020

Pharmacokinetics of linezolid in subjects with renal dysfunction

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Determination of linezolid in plasma by reversed-phase high-performance liquid chromatography

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Linezolid alone and in combination with rifampicin prevents experimental vascular graft infection due to methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis.

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Decreased serum linezolid levels in a critically ill patient receiving concomitant linezolid and rifampin

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Pharmacokinetics and tolerance of linezolid for meticillin-resistant Staphylococcus aureus mediastinitis in paediatric patients

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12 December 2020

Linezolid-induced interstitial nephritis in a kidney-transplant patient

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12 December 2020

Pharmacokinetic evaluation of linezolid in patients with major thermal injuries

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12 December 2020

Use of linezolid, an oxazolidinone, in the treatment of multidrug-resistant gram-positive bacterial infections.

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12 December 2020

Oxidation of the novel oxazolidinone antibiotic linezolid in human liver microsomes.

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12 December 2020

Linezolid pharmacokinetic/pharmacodynamic profile in critically ill septic patients: intermittent versus continuous infusion

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12 December 2020

Linezolid treatment of glycopeptide-resistant Enterococcus faecium in very low birth weight premature neonates

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12 December 2020

Pharmacokinetics and antimicrobial dosing adjustment in critically ill patients during continuous renal replacement therapy

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12 December 2020

Does the dose matter?

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12 December 2020

Impact of ontogeny on linezolid disposition in neonates and infants

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12 December 2020

Pharmacokinetic interactions with rifampicin : clinical relevance

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12 December 2020

Linezolid-induced optic neuropathy: a mitochondrial disorder?

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Toxicity of extended courses of linezolid: results of an Infectious Diseases Society of America Emerging Infections Network survey

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In vivo pharmacodynamics of a new oxazolidinone (linezolid)

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12 December 2020

Good clinical outcomes but high rates of adverse reactions during linezolid therapy for serious infections: a proposed protocol for monitoring therapy in complex patients

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12 December 2020

Serotonin toxicity associated with concomitant use of linezolid

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12 December 2020

Population pharmacokinetics of linezolid in patients treated in a compassionate-use program

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12 December 2020

Comparison of biofilm-associated cell survival following in vitro exposure of meticillin-resistant Staphylococcus aureus biofilms to the antibiotics clindamycin, daptomycin, linezolid, tigecycline and vancomycin

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12 December 2020

Linezolid-resistant Enterococcus faecalis isolated from a cord blood transplant recipient

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12 December 2020

In vitro activity of linezolid alone and in combination with gentamicin, vancomycin or rifampicin against methicillin-resistant Staphylococcus aureus by time-kill curve methods

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12 December 2020

Serotonin syndrome after concomitant treatment with linezolid and meperidine

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12 December 2020

Does haemodialysis significantly affect serum linezolid concentrations in critically ill patients with renal failure? A pilot investigation

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12 December 2020

Does linezolid inhibit its own metabolism? Population pharmacokinetics as a tool to explain the observed nonlinearity in both healthy volunteers and septic patients.

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12 December 2020

Pharmacokinetic/pharmacodynamic factors influencing emergence of resistance to linezolid in an in vitro model

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12 December 2020

In vivo efficacy of continuous infusion versus intermittent dosing of linezolid compared to vancomycin in a methicillin-resistant Staphylococcus aureus rabbit endocarditis model.

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12 December 2020

Linezolid-associated peripheral and optic neuropathy, lactic acidosis, and serotonin syndrome

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12 December 2020

Intrapulmonary pharmacokinetics of linezolid

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12 December 2020

Serum and sputum concentrations following the oral administration of linezolid in adult patients with cystic fibrosis

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12 December 2020

Linezolid pharmacokinetics in adult patients with cystic fibrosis

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12 December 2020

Effect of severity of sepsis on tissue concentrations of linezolid

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12 December 2020

Linezolid disposition after standard dosages in critically ill patients undergoing continuous venovenous hemofiltration: a report of 2 cases

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12 December 2020

Clinical Pharmacokinetics of Linezolid, a Novel Oxazolidinone Antibacterial

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12 December 2020

Pharmacokinetics and pharmacodynamics of linezolid in children with cystic fibrosis

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12 December 2020

Linezolid and rifampin: Drug interaction contrary to expectations?

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12 December 2020

Antimicrobial dosing considerations in obese adult patients

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12 December 2020

Serotonin syndrome as a consequence of drug-resistant infections: an interaction between linezolid and citalopram

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12 December 2020

Can the enhanced renal clearance of antibiotics in cystic fibrosis patients be explained by P-glycoprotein transport?

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12 December 2020

10.2165/11319960-000000000-00000

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DOI

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Dimensions Publication ID

22 August 2017

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