Potential of transglutaminase 2 as a therapeutic target. (Q37776508)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20670177%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

review article

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title

Potential of transglutaminase 2 as a therapeutic target (English)

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8 February 2020

1

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8 February 2020

Monica Currò

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20670177%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Riccardo Ientile

3

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8 February 2020

author name string

Daniela Caccamo

1

1 reference

23 August 2017

Monica Currò

2

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23 August 2017

Riccardo Ientile

3

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23 August 2017

language of work or name

English

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publication date

1 September 2010

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Expert Opinion on Therapeutic Targets

8 February 2020

published in

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8 February 2020

volume

14

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8 February 2020

issue

9

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8 February 2020

page(s)

989-1003

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Transglutaminases: nature's biological glues

8 February 2020

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'Tissue' transglutaminase ablation reduces neuronal death and prolongs survival in a mouse model of Huntington's disease

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Tissue transglutaminase contributes to disease progression in the R6/2 Huntington's disease mouse model via aggregate-independent mechanisms

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Mechanism for the inhibition of transglutaminase 2 by cystamine

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Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease.

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Cystamine inhibits transglutaminase and caspase-3 cleavage in glutamate-exposed astroglial cells

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21 January 2018

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Augmentation of tissue transglutaminase expression and activation by epidermal growth factor inhibit doxorubicin-induced apoptosis in human breast cancer cells

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Transglutaminases: the missing link in nephrogenic systemic fibrosis

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Roles of transglutaminases in cardiac and vascular diseases

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Transglutaminase 2 in the balance of cell death and survival

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Tissue transglutaminase and the stress response

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Human tissue transglutaminase is inhibited by pharmacologic and chemical acetylation

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Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries

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Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells

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Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient

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Transglutaminase 2 ablation leads to defective function of mitochondrial respiratory complex I affecting neuronal vulnerability in experimental models of extrapyramidal disorders.

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Novel transglutaminase inhibitors reverse the inflammation of allergic conjunctivitis

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The role of transglutaminase-2 and its substrates in human diseases

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Transglutaminase Inhibition Reduces Fibrosis and Preserves Function in Experimental Chronic Kidney Disease

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10.1517/14728222.2010.510134

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20670177%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference