Mechanisms, diagnosis and management of hepatic encephalopathy (Q37779485)

23 August 2017

1 reference

title

Mechanisms, diagnosis and management of hepatic encephalopathy (English)

1 reference

23 August 2017

0 references

Ravi Prakash

1

1 reference

23 August 2017

Kevin D Mullen

series ordinal

2

1 reference

23 August 2017

language of work or name

English

0 references

publication date

10 August 2010

1 reference

Nature Reviews Gastroenterology & Hepatology

23 August 2017

1 reference

23 August 2017

7

1 reference

23 August 2017

515-525

1 reference

23 August 2017

9

1 reference

https://scigraph.springernature.com/pub.10.1038/nrgastro.2010.116

23 August 2017

0 references

cites work

Cerebral ammonia metabolism in patients with severe liver disease and minimal hepatic encephalopathy.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Hepatic encephalopathy--definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Role of ammonia and inflammation in minimal hepatic encephalopathy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Systemic inflammatory response exacerbates the neuropsychological effects of induced hyperammonemia in cirrhosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

New concepts in the mechanism of ammonia-induced astrocyte swelling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Pathogenetic interplay between osmotic and oxidative stress: the hepatic encephalopathy paradigm

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

The neurosteroid system: an emerging therapeutic target for hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Can we ignore minimal hepatic encephalopathy any longer?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Influence of recent advances in medical management on clinical outcomes of cirrhosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Review article: the burden of hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Subclinical hepatic encephalopathy impairs daily functioning

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Lactulose improves cognitive functions and health-related quality of life in patients with cirrhosis who have minimal hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Navigation skill impairment: Another dimension of the driving difficulties in minimal hepatic encephalopathy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Patients with minimal hepatic encephalopathy have poor insight into their driving skills

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

The effect of fatigue on driving skills in patients with hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Hepatic encephalopathy and fitness to drive.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Minimal hepatic encephalopathy is associated with motor vehicle crashes: the reality beyond the driving test

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Prognostic significance of hepatic encephalopathy in patients with cirrhosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Pathogenesis of hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Biochemistry and physiology of brain ammonia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Interorgan ammonia, glutamate, and glutamine trafficking in pigs with acute liver failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Interorgan ammonia trafficking in liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Ammonia and hepatic encephalopathy: the more things change, the more they remain the same.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

The syndrome of impending hepatic coma in patients with cirrhosis of the liver given certain nitrogenous substances

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Changes in glutamate-cycle enzyme mRNA levels in a rat model of hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Hepatic encephalopathy in chronic liver disease: a clinical manifestation of astrocyte swelling and low-grade cerebral edema?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Pathogenetic mechanisms of hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Effect of glutamine synthetase inhibition on astrocyte swelling and altered astroglial protein expression during hyperammonemia in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes, an effect of pH.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Effect of ammonia on astrocytic glutamate uptake/release mechanisms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Some metabolic effects of ammonia on astrocytes and neurons in primary cultures

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

1H magnetic resonance in the study of hepatic encephalopathy in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Low grade cerebral edema and the pathogenesis of hepatic encephalopathy in cirrhosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

MR imaging findings in hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Low myo-inositol and high glutamine levels in brain are associated with neuropsychological deterioration after induced hyperammonemia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Pathophysiology of hepatic encephalopathy: The concept of synergism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Morphologic effects of ammonia on primary astrocyte cultures. II. Electron microscopic studies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

The role of astrocytes in hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

The pathophysiologic basis of hepatic encephalopathy: central role for ammonia and inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Astrocyte swelling and protein tyrosine nitration in hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Cachectin/tumor necrosis factor-alpha alters red blood cell kinetics and induces anemia in vivo.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

The influence of cytokines on the integrity of the blood-brain barrier in vitro.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Secretion of interleukin-1beta by astrocytes mediates endothelin-1 and tumour necrosis factor-alpha effects on human brain microvascular endothelial cell permeability.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

In vivo imaging of cerebral "peripheral benzodiazepine binding sites" in patients with hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

The neurosteroid system: implication in the pathophysiology of hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Neurosteroids: a novel function of the brain.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Peripheral-type benzodiazepine receptor in neurosteroid biosynthesis, neuropathology and neurological disorders.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

The "peripheral-type" benzodiazepine (omega 3) receptor in hyperammonemic disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Mild hypothermia prevents brain edema and attenuates up-regulation of the astrocytic benzodiazepine receptor in experimental acute liver failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Ammonia-induced production of free radicals in primary cultures of rat astrocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Activation of N-methyl-D-aspartate receptors in rat brain in vivo following acute ammonia intoxication: characterization by in vivo brain microdialysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Taurine reduces ammonia- and N-methyl-D-aspartate-induced accumulation of cyclic GMP and hydroxyl radicals in microdialysates of the rat striatum.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Hypoosmotic swelling and ammonia increase oxidative stress by NADPH oxidase in cultured astrocytes and vital brain slices

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Glutamine: a Trojan horse in ammonia neurotoxicity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Ammonia induces MK-801-sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Natural benzodiazepines and hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Neurological deficits in "awake" cirrhotic patients on hepatic encephalopathy treatment: missed metabolic or metal disorder?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Manganese deposition in basal ganglia structures results from both portal-systemic shunting and liver dysfunction.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

MR imaging and (1)H spectroscopy of brain metabolites in hepatic encephalopathy: time-course of renormalization after liver transplantation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Reversible Parkinsonism and T1W pallidal hyperintensities in acute liver failure.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Manganese and chronic hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Cirrhosis as a risk factor for sepsis and death: analysis of the National Hospital Discharge Survey.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Spectrum of neurocognitive impairment in cirrhosis: Implications for the assessment of hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

The electroencephalograph in liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Predicting outcome in individual patients after severe head injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Methods for diagnosing hepatic encephalopathy in patients with cirrhosis: a multidimensional approach

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Characteristics of minimal hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Introduction to the Hepatic Encephalopathy Scoring Algorithm (HESA).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Neuropsychological characterization of hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Neuropsychological assessment of hepatic encephalopathy: ISHEN practice guidelines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Neuropsychological changes in a large sample of liver transplant candidates.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Cognitive impairment in people diagnosed with end-stage liver disease evaluated for liver transplantation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Inhibitory control test is a simple method to diagnose minimal hepatic encephalopathy and predict development of overt hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Inhibitory control test for the diagnosis of minimal hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Computerized psychometric testing in minimal encephalopathy and modulation by nitrogen challenge and liver transplant.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Critical flicker frequency for quantification of low-grade hepatic encephalopathy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Diagnostic and prognostic values of critical flicker frequency determination as new diagnostic tool for objective HE evaluation in patients undergoing TIPS implantation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Electroencephalographic analysis for the assessment of hepatic encephalopathy: comparison of non-parametric and parametric spectral estimation techniques.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Correlation between ammonia levels and the severity of hepatic encephalopathy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Lactitol and lactulose for the treatment of subclinical hepatic encephalopathy in cirrhotic patients. A randomised, cross-over study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Lactitol vs. lactulose in the treatment of acute hepatic encephalopathy in cirrhotic patients: a double-blind, randomized trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Lactitol versus lactulose in the treatment of chronic hepatic encephalopathy. A double-blind, randomised, cross-over study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

New mode of action for lactulose

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Management options for minimal hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Therapeutic studies in hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Rifaximin treatment in hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

ESPEN Guidelines on Enteral Nutrition: Liver disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Protein restriction in hepatic encephalopathy: necessary evil or illogical dogma?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Effects of oral branched-chain amino acid granules on event-free survival in patients with liver cirrhosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Branched-chain amino acids for hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Vegetarian diets in hepatic encephalopathy: facts or fantasies?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Review article: the modern management of hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Hepatic encephalopathy as a predictor of survival in patients with end-stage liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Management of refractory hepatic encephalopathy after insertion of TIPS: long-term results of shunt reduction with hourglass-shaped balloon-expandable stent-graft

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Activation of soluble guanylate cyclase by nitric oxide in lymphocytes correlates with minimal hepatic encephalopathy in cirrhotic patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Cyclic GMP in blood and minimal hepatic encephalopathy: fine-tuning of the diagnosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Sodium benzoate in the treatment of acute hepatic encephalopathy: a double-blind randomized trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Therapeutic efficacy of L-ornithine-L-aspartate infusions in patients with cirrhosis and hepatic encephalopathy: results of a placebo-controlled, double-blind study.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Clinical efficacy of L-ornithine-L-aspartate in the management of hepatic encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.116

Zinc supplementation and amino acid-nitrogen metabolism in patients with advanced cirrhosis

31 March 2020

1 reference

12 December 2020

Management of hepatic encephalopathy with oral zinc supplementation: a long-term treatment

1 reference

12 December 2020

Successful use of bromocriptine in the treatment of chronic hepatic encephalopathy

1 reference

12 December 2020

The metabolic fate of 13N-labeled ammonia in rat brain

1 reference

12 December 2020

Effects of tumor necrosis factor-alpha and interleukin-6 on fluid-phase permeability and ammonia diffusion in CNS-derived endothelial cells.

1 reference

12 December 2020

A case of liver cirrhosis associated with chronic subdural hematoma and hepatic encephalopathy

1 reference

12 December 2020

Comparison of lactulose and neomycin in the treatment of chronic portal-systemic encephalopathy. A double blind controlled trial

1 reference

12 December 2020

10.1038/NRGASTRO.2010.116

Identifiers

DOI

1 reference

Dimensions Publication ID

23 August 2017

0 references

1 reference