Notch signaling in cardiac development and disease. (Q37785202)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20816401%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Notch signaling in cardiac development and disease (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20816401%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20816401%20AND%20SRC:MED&resulttype=core&format=json

José Luis De La Pompa Mínguez

13 February 2020

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20816401%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Meritxell Nus

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20816401%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

publication date

1 January 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20816401%20AND%20SRC:MED&resulttype=core&format=json

Current Topics in Developmental Biology

13 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20816401%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

92

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20816401%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

333-365

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20816401%20AND%20SRC:MED&resulttype=core&format=json

Sequential myofibrillar breakdown accompanies mitotic division of mammalian cardiomyocytes

13 February 2020

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The bicuspid aortic valve

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Notch activates cell cycle reentry and progression in quiescent cardiomyocytes.

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BMP10 is essential for maintaining cardiac growth during murine cardiogenesis

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Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.

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Notch1 signaling stimulates proliferation of immature cardiomyocytes

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A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition

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Bicuspid aortic valve is heritable

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Control of the adaptive response of the heart to stress via the Notch1 receptor pathway.

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Mutations in JAGGED1 gene are predominantly sporadic in Alagille syndrome

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Monitoring Notch1 activity in development: evidence for a feedback regulatory loop

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Tetralogy of fallot and other congenital heart defects in Hey2 mutant mice

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The fuzzy logic of physiological cardiac hypertrophy

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Phenotyping hypertrophy: eschew obfuscation

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Dosage-sensitive requirement for mouse Dll4 in artery development

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Familial Tetralogy of Fallot caused by mutation in the jagged1 gene

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Neuregulins: functions, forms, and signaling strategies

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7 January 2021

The Notch target genes Hey1 and Hey2 are required for embryonic vascular development

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7 January 2021

Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition

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7 January 2021

Mutations in NOTCH1 cause aortic valve disease

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7 January 2021

Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

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7 January 2021

The molecular logic of Notch signaling--a structural and biochemical perspective.

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7 January 2021

De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot

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7 January 2021

Notch signaling is essential for ventricular chamber development

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7 January 2021

The tetralogy of Fallot-associated G274D mutation impairs folding of the second epidermal growth factor repeat in Jagged-1.

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7 January 2021

Activation of Notch-mediated protective signaling in the myocardium

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7 January 2021

Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation

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7 January 2021

A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development.

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https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development

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7 January 2021

Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanisms

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7 January 2021

Synergistic roles of neuregulin-1 and insulin-like growth factor-I in activation of the phosphatidylinositol 3-kinase pathway and cardiac chamber morphogenesis

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https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

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https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Hypoplastic left heart syndrome is heritable

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7 January 2021

A prospective study to assess the frequency of familial clustering of congenital bicuspid aortic valve

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

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7 January 2021

Thermodynamic analysis of the CSL x Notch interaction: distribution of binding energy of the Notch RAM region to the CSL beta-trefoil domain and the mode of competition with the viral transactivator EBNA2.

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7 January 2021

Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes

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7 January 2021

Hesr, a mediator of the Notch signaling, functions in heart and vessel development

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7 January 2021

Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system

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7 January 2021

Targeted disruption of hesr2 results in atrioventricular valve anomalies that lead to heart dysfunction

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7 January 2021

Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2

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7 January 2021

Molecular insights into segmentation along the proximal-distal axis of the nephron.

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7 January 2021

The canonical Notch signaling pathway: unfolding the activation mechanism

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7 January 2021

Spectrum and frequency of jagged1 (JAG1) mutations in Alagille syndrome patients and their families

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7 January 2021

Jagged1 mutations in patients ascertained with isolated congenital heart defects

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7 January 2021

Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart

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7 January 2021

Familial deafness, congenital heart defects, and posterior embryotoxon caused by cysteine substitution in the first epidermal-growth-factor-like domain of jagged 1.

1 reference

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7 January 2021

Requirement for neuregulin receptor erbB2 in neural and cardiac development

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

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7 January 2021

Echocardiographic evaluation of asymptomatic parental and sibling cardiovascular anomalies associated with congenital left ventricular outflow tract lesions

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https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

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https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Epidemiology of cardiovascular malformations: prevalence and risk factors

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7 January 2021

Prevalence of congenital cardiovascular malformations among relatives of infants with hypoplastic left heart, coarctation of the aorta, and d-transposition of the great arteries.

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7 January 2021

Left ventricular hypertrophy: pathogenesis, detection, and prognosis

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7 January 2021

Conditional JAG1 mutation shows the developing heart is more sensitive than developing liver to JAG1 dosage

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https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning

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https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Structural development of endocardial cushions

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https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Evidence in favor of linkage to human chromosomal regions 18q, 5q and 13q for bicuspid aortic valve and associated cardiovascular malformations

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7 January 2021

O-linked N-acetylglucosamine is present on the extracellular domain of notch receptors

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https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Inheritance analysis of congenital left ventricular outflow tract obstruction malformations: Segregation, multiplex relative risk, and heritability.

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7 January 2021

NOTCH1 mutations in individuals with left ventricular outflow tract malformations reduce ligand-induced signaling

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7 January 2021

Linkage analysis of left ventricular outflow tract malformations (aortic valve stenosis, coarctation of the aorta, and hypoplastic left heart syndrome).

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7 January 2021

NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway

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7 January 2021

Analysis of cardiovascular phenotype and genotype-phenotype correlation in individuals with a JAG1 mutation and/or Alagille syndrome

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7 January 2021

Novel NOTCH1 mutations in patients with bicuspid aortic valve disease and thoracic aortic aneurysms

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7 January 2021

Differences between pathological and physiological cardiac hypertrophy: novel therapeutic strategies to treat heart failure

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

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7 January 2021

Multiple essential functions of neuregulin in development

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7 January 2021

Novel missense mutations (p.T596M and p.P1797H) in NOTCH1 in patients with bicuspid aortic valve

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7 January 2021

Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate

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7 January 2021

Defective intracellular transport and processing of JAG1 missense mutations in Alagille syndrome

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7 January 2021

HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments

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7 January 2021

Presenilin 1 is essential for cardiac morphogenesis

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7 January 2021

Induction of cardiogenesis in embryonic stem cells via downregulation of Notch1 signaling

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7 January 2021

Notch1 represses osteogenic pathways in aortic valve cells

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7 January 2021

Mutations in the human Jagged1 gene are responsible for Alagille syndrome

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7 January 2021

Calcific aortic valve disease: outflow obstruction is the end stage of a systemic disease process

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7 January 2021

An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart

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7 January 2021

Structure-function analysis of delta trafficking, receptor binding and signaling in Drosophila

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7 January 2021

Cell biology of cardiac cushion development.

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7 January 2021

Progressive cardiac conduction defect is the prevailing phenotype in carriers of a Brugada syndrome SCN5A mutation

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Calcific aortic stenosis: an update

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Degenerative aortic stenosis

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7 January 2021

Somatic mutations in cardiac malformations

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7 January 2021

Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

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7 January 2021

Neuregulin-1 promotes formation of the murine cardiac conduction system

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7 January 2021

Bmp2 instructs cardiac progenitors to form the heart-valve-inducing field

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7 January 2021

Hes1 is expressed in the second heart field and is required for outflow tract development

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7 January 2021

Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors

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7 January 2021

Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the Alagille syndrome hepatic phenotype.

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7 January 2021

Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2.

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7 January 2021

The spectrum of cardiovascular anomalies in CHF1/Hey2 deficient mice reveals roles in endocardial cushion, myocardial and vascular maturation

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7 January 2021

Recombination signal sequence-binding protein Jkappa alters mesodermal cell fate decisions by suppressing cardiomyogenesis

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7 January 2021

The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis

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7 January 2021

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods

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7 January 2021

Genetic modifiers in human development and malformation syndromes, including chaperone proteins

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7 January 2021

Jagged1 mutations in alagille syndrome

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7 January 2021

Regulation of Notch signaling by glycosylation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

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7 January 2021

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

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https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Molecular determinants of left and right outflow tract obstruction

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Normal stages of cardiac organogenesis in the mouse: II. Development of the internal relief of the heart

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Jagged1 (JAG1) mutations in Alagille syndrome: increasing the mutation detection rate

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Autosomal dominant inheritance of left ventricular outflow tract obstruction

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Activated notch inhibits myogenic activity of the MADS-Box transcription factor myocyte enhancer factor 2C

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Regions of Drosophila Notch that contribute to ligand binding and the modulatory influence of Fringe.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Common pathogenic features of atherosclerosis and calcific aortic stenosis: role of transforming growth factor-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: role of Smad1 and extracellular signal-regulated kinase 1/2

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

gridlock, an HLH gene required for assembly of the aorta in zebrafish

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2810%2992011-5

7 January 2021

10.1016/S0070-2153(10)92011-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20816401%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference