Mechanisms of genetic regulation in gene expression: examples from drug metabolizing enzymes and transporters (Q37791990)

23 August 2017

Mechanisms of genetic regulation in gene expression: examples from drug metabolizing enzymes and transporters (English)

1 reference

23 August 2017

1

Dylan M Glubb

1 reference

23 August 2017

2

Federico Innocenti

1 reference

23 August 2017

23 September 2010

1 reference

Wiley interdisciplinary reviews. Systems biology and medicine

23 August 2017

1 reference

23 August 2017

3

1 reference

23 August 2017

3

1 reference

23 August 2017

299-313

1 reference

Polymorphisms affecting gene regulation and mRNA processing: broad implications for pharmacogenetics

23 August 2017

1 reference

Pharmacogenetics/genomics of membrane transporters in cancer chemotherapy

21 January 2018

1 reference

Intra- and interspecific variation in primate gene expression patterns

21 January 2018

1 reference

Coordinated control of the gene expression machinery

21 January 2018

1 reference

Regulation of mRNA translation by 5'- and 3'-UTR-binding factors

21 January 2018

1 reference

Expansion of the eukaryotic proteome by alternative splicing

21 January 2018

1 reference

Systems perspectives on mRNA processing

21 January 2018

1 reference

The ontogeny of human drug-metabolizing enzymes: phase I oxidative enzymes

21 January 2018

1 reference

The ontogeny of human drug-metabolizing enzymes: phase II conjugation enzymes and regulatory mechanisms

21 January 2018

1 reference

Transporters and drug therapy: implications for drug disposition and disease

21 January 2018

1 reference

Epigenetic interplay between histone modifications and DNA methylation in gene silencing

21 January 2018

1 reference

CpG islands as gene markers in the human genome.

21 January 2018

1 reference

Pharmacoepigenetics: its role in interindividual differences in drug response

21 January 2018

1 reference

Epigenetic regulation of genes encoding drug-metabolizing enzymes and transporters; DNA methylation and other mechanisms

21 January 2018

1 reference

Epigenetic and microRNA-dependent control of cytochrome P450 expression: a gap between DNA and protein

21 January 2018

1 reference

Aberrant methylation of DPYD promoter, DPYD expression, and cellular sensitivity to 5-fluorouracil in cancer cells

21 January 2018

1 reference

Computational and experimental identification of novel human imprinted genes

21 January 2018

1 reference

Intra-individual change over time in DNA methylation with familial clustering

21 January 2018

1 reference

Epigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylation

21 January 2018

1 reference

Regulatory functions of 3'UTRs.

21 January 2018

1 reference

MicroRNAs: Small regulators with a big impact

21 January 2018

1 reference

An evolutionary perspective of animal microRNAs and their targets

21 January 2018

1 reference

MicroRNAs and pharmacogenomics

21 January 2018

1 reference

Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells

21 January 2018

1 reference

Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin.

21 January 2018

1 reference

Escape from hsa-miR-519c enables drug-resistant cells to maintain high expression of ABCG2.

21 January 2018

1 reference

MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells

21 January 2018

1 reference

Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1.

21 January 2018

1 reference

Genome-wide transcriptional profiling reveals microRNA-correlated genes and biological processes in human lymphoblastoid cell lines

21 January 2018

1 reference

Transcription regulation and animal diversity

21 January 2018

1 reference

Eukaryotic regulatory element conservation analysis and identification using comparative genomics

21 January 2018

1 reference

Functional evolution of noncoding DNA.

21 January 2018

1 reference

TRANSFAC: a database on transcription factors and their DNA binding sites

21 January 2018

1 reference

JASPAR: an open-access database for eukaryotic transcription factor binding profiles

21 January 2018

1 reference

A unified theory of gene expression

21 January 2018

1 reference

Genome-wide analysis of factors regulating gene expression in liver

21 January 2018

1 reference

Predicting tissue-specific enhancers in the human genome

21 January 2018

1 reference

Nuclear receptors and drug disposition gene regulation

21 January 2018

1 reference

Nuclear receptor-mediated transcriptional regulation in Phase I, II, and III xenobiotic metabolizing systems

21 January 2018

1 reference

Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism

21 January 2018

1 reference

Global variation in copy number in the human genome

21 January 2018

1 reference

Relative impact of nucleotide and copy number variation on gene expression phenotypes

21 January 2018

1 reference

Identification of copy number variants defining genomic differences among major human groups

21 January 2018

1 reference

An initial map of insertion and deletion (INDEL) variation in the human genome.

21 January 2018

1 reference

The patterns of natural variation in human genes

21 January 2018

1 reference

Quality control of human ABCG2 protein in the endoplasmic reticulum: ubiquitination and proteasomal degradation

21 January 2018

1 reference

Mammalian mutation pressure, synonymous codon choice, and mRNA degradation

21 January 2018

1 reference

A synonymous SNP of the corneodesmosin gene leads to increased mRNA stability and demonstrates association with psoriasis across diverse ethnic groups

21 January 2018

1 reference

Codon bias as a factor in regulating expression via translation rate in the human genome.

21 January 2018

1 reference

A "silent" polymorphism in the MDR1 gene changes substrate specificity

21 January 2018

1 reference

Clinical aspects of the MDR1 (ABCB1) gene polymorphism

21 January 2018

1 reference

A complex intronic splicing enhancer from the c-src pre-mRNA activates inclusion of a heterologous exon

21 January 2018

1 reference

Exonic splicing enhancers contribute to the use of both 3' and 5' splice site usage of rat beta-tropomyosin pre-mRNA

21 January 2018

1 reference

Genetic variation in the proximal promoter of ABC and SLC superfamilies: liver and kidney specific expression and promoter activity predict variation

21 January 2018

1 reference

Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism?

21 January 2018

1 reference

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan

21 January 2018

1 reference

Pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 polymorphisms: are we there yet?

21 January 2018

1 reference

Identification of genetic variants contributing to cisplatin-induced cytotoxicity by use of a genomewide approach

21 January 2018

1 reference

Genetic variants contributing to daunorubicin-induced cytotoxicity

21 January 2018

1 reference

Identification of genetic variants and gene expression relationships associated with pharmacogenes in humans

21 January 2018

1 reference

Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines

21 January 2018

1 reference

Common regulatory variation impacts gene expression in a cell type-dependent manner

21 January 2018

1 reference

Mapping the genetic architecture of gene expression in human liver

21 January 2018

1 reference

Expression quantitative trait loci detected in cell lines are often present in primary tissues

21 January 2018

1 reference

SCAN: SNP and copy number annotation

21 January 2018

1 reference

Differential allelic expression in the human genome: a robust approach to identify genetic and epigenetic cis-acting mechanisms regulating gene expression

21 January 2018

1 reference

Large scale real-time PCR validation on gene expression measurements from two commercial long-oligonucleotide microarrays

21 January 2018

1 reference

Direct selection of human genomic loci by microarray hybridization

21 January 2018

1 reference

RNA-Seq: a revolutionary tool for transcriptomics

21 January 2018

1 reference

RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays

21 January 2018

1 reference

Predicting potentially functional SNPs in drug-response genes.

21 January 2018

1 reference

Bioinformatic tools for identifying disease gene and SNP candidates

21 January 2018

1 reference

Functional implications of genetic variation in non-coding DNA for disease susceptibility and gene regulation

21 January 2018

1 reference

Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences

21 January 2018

1 reference

Defining the sequence-recognition profile of DNA-binding molecules

21 January 2018

1 reference

Chromatin immunoprecipitation (ChIP) methodology and readouts

21 January 2018

1 reference

A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network

21 January 2018

1 reference

Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo

21 January 2018

1 reference

ChIP on chip assays: genome-wide analysis of transcription factor binding and histone modifications

21 January 2018

1 reference

Using ChIP-chip and ChIP-seq to study the regulation of gene expression: genome-wide localization studies reveal widespread regulation of transcription elongation

21 January 2018

1 reference

Profiling of promoter occupancy by PPARalpha in human hepatoma cells via ChIP-chip analysis

21 January 2018

1 reference

ChIP-seq: advantages and challenges of a maturing technology

21 January 2018

1 reference

Genetic and epigenetic regulation and expression signatures of glutathione S-transferases in developing mouse liver

21 January 2018

1 reference

A genome-wide association study of acenocoumarol maintenance dosage.

21 January 2018

1 reference

A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose

21 January 2018

1 reference

A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/WSBM.125

1 reference

23 August 2017

1 reference

PubMed ID

20865777